Growth Metrics

Soleno Therapeutics (SLNO) EBITDA (2013 - 2026)

Soleno Therapeutics (SLNO) reported EBITDA of $29.1 million for Q1 2026, up 166.33% year-over-year from $10.9 million in Q1 2025, and down 32.91% on a QoQ basis from $43.4 million in Q4 2025.

Soleno Therapeutics (SLNO) has 14 years of EBITDA data on file, last reported at $29.1 million in Q1 2026.

  • Quarterly EBITDA rose 166.33% year-over-year to $29.1 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $94.0 million (up 147.49% YoY) and the FY2025 annual result came in at $20.9 million, up 111.93% from the prior year.
  • EBITDA declined to $29.1 million in Q1 2026 per SLNO's latest filing, from $43.4 million in the prior quarter.
  • Across five years, EBITDA topped out at $43.4 million in Q4 2025 and bottomed at -$75.6 million in Q3 2024.
  • The 5-year median for EBITDA is -$8.3 million (2023), against an average of -$11.1 million.
  • The widest annual swing landed in 2024, when EBITDA tumbled 595.71%; it then jumped 176.82% in 2025.
  • Tracing SLNO's EBITDA over 5 years: stood at -$5.5 million in 2022, then sank by 105.96% to -$11.3 million in 2023, then sank by 400.36% to -$56.5 million in 2024, then jumped by 176.82% to $43.4 million in 2025, then plunged by 32.91% to $29.1 million in 2026.
  • Per Business Quant, the three latest SLNO EBITDA figures stand at $29.1 million (Q1 2026), $43.4 million (Q4 2025), and $26.3 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Quantum Biopharma 1,216,509.61 Bn 1,216,509.61 Bn - -13.63 Mn
2 Alterity Therapeutics 764,224.41 Bn 764,224.38 Bn - -
3 Legend Biotech 2,716.00 Bn 2,715.71 Bn 242.10 Mn -19.70 Mn
4 Nanobiotix 2,248.83 Bn 2,248.77 Bn - -
5 Akari Therapeutics 1,951.18 Bn 1,951.17 Bn - -14.44 Mn
6 Vertex Pharmaceuticals 113.69 Bn 106.44 Bn 2.59 Bn 1.14 Bn
7 Evaxion A 64.16 Bn 64.14 Bn - -3.82 Mn
8 Regeneron Pharmaceuticals 63.94 Bn 55.18 Bn 3.31 Bn 661.60 Mn
9 Alnylam Pharmaceuticals 40.13 Bn 37.12 Bn 959.66 Mn 201.19 Mn
10 Soleno Therapeutics 2.76 Bn 2.51 Bn 93.41 Mn 29.13 Mn

Historic Data

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DateValue
Mar 31, 2026 29.13 Mn
Dec 31, 2025 43.41 Mn
Sep 30, 2025 26.29 Mn
Jun 30, 2025 -4.85 Mn
Mar 31, 2025 -43.91 Mn
Dec 31, 2024 -56.52 Mn
Sep 30, 2024 -75.57 Mn
Jun 30, 2024 -21.90 Mn
Mar 31, 2024 -21.50 Mn
Dec 31, 2023 -11.30 Mn
Sep 30, 2023 -10.86 Mn
Jun 30, 2023 -8.49 Mn
Mar 31, 2023 -8.34 Mn
Dec 31, 2022 -5.48 Mn
Sep 30, 2022 -6.13 Mn
Jun 30, 2022 -6.72 Mn
Mar 31, 2022 -5.73 Mn
Dec 31, 2021 -3.00 Mn
Sep 30, 2021 -8.14 Mn
Jun 30, 2021 -10.99 Mn
Mar 31, 2021 -8.95 Mn
Dec 31, 2020 -7.96 Mn
Sep 30, 2020 -7.86 Mn
Jun 30, 2020 -11.19 Mn
Mar 31, 2020 -9.28 Mn
Dec 31, 2019 -6.75 Mn
Sep 30, 2019 -6.13 Mn
Jun 30, 2019 -5.62 Mn
Mar 31, 2019 -4.98 Mn
Dec 31, 2018 -3.54 Mn
Sep 30, 2018 -3.88 Mn
Jun 30, 2018 -3.41 Mn
Mar 31, 2018 -3.48 Mn
Dec 31, 2017 -5.20 Mn
Sep 30, 2017 -2.63 Mn
Jun 30, 2017 -2.97 Mn
Mar 31, 2017 -1.37 Mn
Dec 31, 2016 -1.83 Mn
Sep 30, 2016 -1.97 Mn
Jun 30, 2016 -2.30 Mn
Mar 31, 2016 -4.26 Mn
Dec 31, 2015 -3.51 Mn
Sep 30, 2015 -3.18 Mn
Jun 30, 2015 -3.04 Mn
Mar 31, 2015 -2.43 Mn
Dec 31, 2014 -1.85 Mn
Sep 30, 2014 -1.32 Mn
Jun 30, 2014 -1.31 Mn
Mar 31, 2014 -684,000.00
Dec 31, 2013 -559,783.00
Sep 30, 2013 -993,000.00