Soleno Therapeutics (SLNO) Operating Income (2013 - 2026)

Soleno Therapeutics' (SLNO) quarterly Operating Income came in at $31.3 million in Q1 2026, up 168.38% year-on-year from $11.7 million in Q1 2025, and down 20.97% on a QoQ basis from $39.6 million in Q4 2025.

Soleno Therapeutics (SLNO) Operating Income (2013 - 2026) Analysis & Trends

Soleno Therapeutics (SLNO) has 14 years of Operating Income data on file, last reported at $31.3 million in Q1 2026.

  • On a quarterly basis, Operating Income rose 168.38% year-over-year to $31.3 million in Q1 2026; TTM through Mar 2026 was $86.4 million, a 141.17% increase from a year earlier, with the FY2025 full-year figure at $9.4 million, up 105.02% from the prior year.
  • Operating Income for Q1 2026 stood at $31.3 million, down from $39.6 million in the prior quarter.
  • Over the last five years, Operating Income for SLNO reached as high as $39.6 million in Q4 2025 and fell as low as -$80.2 million in Q3 2024.
  • Historically, Operating Income has averaged -$12.5 million across 5 years, with a median of -$8.5 million in 2023.
  • Across the five-year window, Operating Income sank 672.61% in 2024 and surged 168.38% in 2026, its largest moves.
  • Year by year, Operating Income stood at -$5.6 million in 2022, then slumped by 147.95% to -$13.9 million in 2023, then plunged by 324.99% to -$59.1 million in 2024, then surged by 166.95% to $39.6 million in 2025, then dropped by 20.97% to $31.3 million in 2026.
  • Per Business Quant data, the three most recent Operating Income figures were $31.3 million in Q1 2026, $39.6 million in Q4 2025, and $22.1 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -27.75 Mn
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -15.76 Mn
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 249.90 Mn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 1.14 Bn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 642.90 Mn
7 Belite Bio 61.40 Bn 61.40 Bn - -32.68 Mn
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn 394.00 Mn
9 Revolution Medicines 37.37 Bn 37.37 Bn - -445.22 Mn
10 Soleno Therapeutics 874.25 Mn 618.67 Mn 93.41 Mn 31.28 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 31.28 Mn
Dec 31, 2025 39.58 Mn
Sep 30, 2025 22.11 Mn
Jun 30, 2025 -6.53 Mn
Mar 31, 2025 -45.74 Mn
Dec 31, 2024 -59.12 Mn
Sep 30, 2024 -80.21 Mn
Jun 30, 2024 -24.87 Mn
Mar 31, 2024 -23.48 Mn
Dec 31, 2023 -13.91 Mn
Sep 30, 2023 -10.38 Mn
Jun 30, 2023 -8.62 Mn
Mar 31, 2023 -8.47 Mn
Dec 31, 2022 -5.61 Mn
Sep 30, 2022 -6.24 Mn
Jun 30, 2022 -6.78 Mn
Mar 31, 2022 -5.77 Mn
Dec 31, 2021 -3.00 Mn
Sep 30, 2021 -8.29 Mn
Jun 30, 2021 -11.09 Mn