Soleno Therapeutics (SLNO) Operating Income (2013 - 2026)
Soleno Therapeutics (SLNO) posted quarterly Operating Income of $31.3 million for Q1 2026, up 168.38% year-over-year from $11.7 million in Q1 2025, and down 20.97% quarter-over-quarter from $39.6 million in Q4 2025.
Soleno Therapeutics (SLNO) Operating Income (2013 - 2026) Analysis & Trends
Soleno Therapeutics (SLNO) has reported Operating Income for 14 consecutive years, with $31.3 million the latest figure, recorded in Q1 2026.
- In Q1 2026, Operating Income rose 168.38% year-over-year to $31.3 million; the TTM figure through Mar 2026 stood at $86.4 million (up 141.17% YoY), while the FY2025 annual figure was $9.4 million, up 105.02% from the prior year.
- Operating Income slipped to $31.3 million in Q1 2026 per SLNO's latest filing, from $39.6 million in the prior quarter.
- Across five years, Operating Income topped out at $39.6 million in Q4 2025 and bottomed at -$80.2 million in Q3 2024.
- Historically, Operating Income has averaged -$12.5 million across 5 years, with a median of -$8.5 million in 2023.
- Annual changes were most pronounced in 2024 — Operating Income tumbled 672.61% — and 2026, when it jumped 168.38%.
- Soleno Therapeutics' Operating Income stood at -$5.6 million in 2022, then slumped by 147.95% to -$13.9 million in 2023, then plunged by 324.99% to -$59.1 million in 2024, then soared by 166.95% to $39.6 million in 2025, then decreased by 20.97% to $31.3 million in 2026.
- Business Quant data shows SLNO's Operating Income at $31.3 million in Q1 2026, $39.6 million in Q4 2025, and $22.1 million in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Op. Inc (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 128.13 Bn | 120.28 Bn | 2.84 Bn | 1.25 Bn |
| 2 | Regeneron Pharmaceuticals | 112.33 Bn | 104.33 Bn | 3.93 Bn | 1.29 Bn |
| 3 | Argenx Se | 53.24 Bn | 48.05 Bn | 1.41 Bn | 493.00 Mn |
| 4 | Revolution Medicines | 43.64 Bn | 43.64 Bn | - | -505.13 Mn |
| 5 | BeOne Medicines | 39.27 Bn | 34.17 Bn | 1.53 Bn | 325.05 Mn |
| 6 | MindWalk Holdings | 35.32 Bn | 35.31 Bn | 1.82 Bn | -3,158.03 |
| 7 | Royalty Pharma | 33.72 Bn | 35.84 Bn | - | 133.12 Mn |
| 8 | Alnylam Pharmaceuticals | 30.58 Bn | 27.27 Bn | 992.69 Mn | 231.44 Mn |
| 9 | Insmed | 27.01 Bn | 25.85 Bn | 358.27 Mn | -1.55 Mn |
| 10 | Soleno Therapeutics | 2.74 Bn | 2.49 Bn | 93.41 Mn | 31.28 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 31.28 Mn |
| Dec 31, 2025 | 39.58 Mn |
| Sep 30, 2025 | 22.11 Mn |
| Jun 30, 2025 | -6.53 Mn |
| Mar 31, 2025 | -45.74 Mn |
| Dec 31, 2024 | -59.12 Mn |
| Sep 30, 2024 | -80.21 Mn |
| Jun 30, 2024 | -24.87 Mn |
| Mar 31, 2024 | -23.48 Mn |
| Dec 31, 2023 | -13.91 Mn |
| Sep 30, 2023 | -10.38 Mn |
| Jun 30, 2023 | -8.62 Mn |
| Mar 31, 2023 | -8.47 Mn |
| Dec 31, 2022 | -5.61 Mn |
| Sep 30, 2022 | -6.24 Mn |
| Jun 30, 2022 | -6.78 Mn |
| Mar 31, 2022 | -5.77 Mn |
| Dec 31, 2021 | -3.00 Mn |
| Sep 30, 2021 | -8.29 Mn |
| Jun 30, 2021 | -11.09 Mn |