Soleno Therapeutics (SLNO) Enterprise Value (2013 - 2026)

Soleno Therapeutics (SLNO) posted quarterly Enterprise Value of -$255.6 million for Q1 2026, up 11.85% year-over-year from -$228.5 million in Q1 2025, and up 16.34% quarter-over-quarter from -$305.5 million in Q4 2025.

Soleno Therapeutics (SLNO) Enterprise Value (2013 - 2026) Analysis & Trends

Soleno Therapeutics (SLNO) has reported Enterprise Value for 14 consecutive years, with -$255.6 million the latest figure, recorded in Q1 2026.

  • In Q1 2026, Enterprise Value rose 11.85% year-over-year to -$255.6 million; the TTM figure through Mar 2026 stood at -$255.6 million (up 11.85% YoY), while the FY2025 annual figure was -$305.5 million, down 4.82% from the prior year.
  • Enterprise Value advanced to -$255.6 million in Q1 2026 per SLNO's latest filing, from -$305.5 million in the prior quarter.
  • Across five years, Enterprise Value topped out at -$7.9 million in Q1 2023 and bottomed at -$499.0 million in Q3 2025.
  • Historically, Enterprise Value has averaged -$172.8 million across 5 years, with a median of -$169.7 million in 2023.
  • Annual changes were most pronounced in 2023 — Enterprise Value soared 72.73% — and 2024, when it slumped 1793.67%.
  • Soleno Therapeutics' Enterprise Value stood at -$14.6 million in 2022, then tumbled by 1062.04% to -$169.7 million in 2023, then sank by 71.76% to -$291.4 million in 2024, then dropped by 4.82% to -$305.5 million in 2025, then advanced by 16.34% to -$255.6 million in 2026.
  • Business Quant data shows SLNO's Enterprise Value at -$255.6 million in Q1 2026, -$305.5 million in Q4 2025, and -$499.0 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Enterprise Value (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn -7.85 Bn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn -7.99 Bn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn -5.18 Bn
4 Revolution Medicines 43.64 Bn 43.64 Bn - -3.94 Bn
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn -5.10 Bn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -8.46 Mn
7 Royalty Pharma 33.72 Bn 35.84 Bn - 2.12 Bn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn -3.31 Bn
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -1.16 Bn
10 Soleno Therapeutics 2.74 Bn 2.49 Bn 93.41 Mn -255.57 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -255.57 Mn
Dec 31, 2025 -305.47 Mn
Sep 30, 2025 -498.97 Mn
Jun 30, 2025 -286.84 Mn
Mar 31, 2025 -289.93 Mn
Dec 31, 2024 -291.44 Mn
Sep 30, 2024 -256.78 Mn
Jun 30, 2024 -266.10 Mn
Mar 31, 2024 -149.60 Mn
Dec 31, 2023 -169.68 Mn
Sep 30, 2023 -52.40 Mn
Jun 30, 2023 -19.40 Mn
Mar 31, 2023 -7.90 Mn
Dec 31, 2022 -14.60 Mn
Sep 30, 2022 -19.75 Mn
Jun 30, 2022 -24.10 Mn
Mar 31, 2022 -28.97 Mn
Dec 31, 2021 -21.30 Mn
Sep 30, 2021 -28.19 Mn
Jun 30, 2021 -33.60 Mn