Growth Metrics

C4 Therapeutics (CCCC) EBITDA Margin (2019 - 2025)

C4 Therapeutics' EBITDA Margin history spans 7 years, with the latest figure at 186.78% for Q4 2025.

  • For Q4 2025, EBITDA Margin rose 48880.0% year-over-year to 186.78%; the TTM value through Dec 2025 reached 292.24%, up 322.0%, while the annual FY2025 figure was 292.09%, 337.0% up from the prior year.
  • EBITDA Margin reached 186.78% in Q4 2025 per CCCC's latest filing, up from 285.39% in the prior quarter.
  • In the past five years, EBITDA Margin ranged from a high of 81.07% in Q4 2021 to a low of 1322.3% in Q2 2023.
  • Average EBITDA Margin over 5 years is 496.37%, with a median of 327.6% recorded in 2021.
  • Peak YoY movement for EBITDA Margin: crashed -117727bps in 2022, then soared 117424bps in 2024.
  • A 5-year view of EBITDA Margin shows it stood at 81.07% in 2021, then tumbled by -1452bps to 1258.34% in 2022, then increased by 17bps to 1041.92% in 2023, then skyrocketed by 35bps to 675.58% in 2024, then soared by 72bps to 186.78% in 2025.
  • Per Business Quant, the three most recent readings for CCCC's EBITDA Margin are 186.78% (Q4 2025), 285.39% (Q3 2025), and 403.73% (Q2 2025).