Growth Metrics

C4 Therapeutics (CCCC) Operating Income (2019 - 2026)

C4 Therapeutics' quarterly Operating Income came in at -$27.8 million in Q1 2026, up 4.73% year-on-year from -$26.5 million in Q1 2025, and down 20.05% quarter-over-quarter from -$23.1 million in Q4 2025.

C4 Therapeutics has reported Operating Income for 8 years, with the latest figure at -$27.8 million in Q1 2026.

  • For the quarter ending Q1 2026, Operating Income rose 4.73% year-over-year to -$27.8 million; the trailing twelve-month figure through Mar 2026 stood at -$113.8 million (up 2.33% YoY), and the FY2025 full-year result was -$115.2 million, up 3.67% from the prior year.
  • Operating Income for Q1 2026 stood at -$27.8 million, down from -$23.1 million in the prior quarter.
  • The five-year high for Operating Income was -$21.4 million in Q2 2024, with the low at -$38.3 million in Q4 2022.
  • Average Operating Income over 5 years is -$31.2 million, with a median of -$31.4 million recorded in 2022.
  • Year-over-year, Operating Income plunged 151.02% in 2022 and jumped 42.92% in 2024.
  • Tracing CCCC's Operating Income over 5 years: stood at -$38.3 million in 2022, then climbed by 2.26% to -$37.4 million in 2023, then slipped by 0.75% to -$37.7 million in 2024, then jumped by 38.62% to -$23.1 million in 2025, then retreated by 20.05% to -$27.8 million in 2026.
  • The last three Operating Income figures came in at -$27.8 million (Q1 2026), -$23.1 million (Q4 2025), and -$34.4 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -2.97 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -19.70 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -15.76 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 1.14 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - -3.82 Mn
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 642.90 Mn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 268.64 Mn
10 C4 Therapeutics 561.03 Mn 325.36 Mn - -27.79 Mn

Historic Data

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DateValue
Mar 31, 2026 -27.79 Mn
Dec 31, 2025 -23.15 Mn
Sep 30, 2025 -34.41 Mn
Jun 30, 2025 -28.50 Mn
Mar 31, 2025 -29.16 Mn
Dec 31, 2024 -37.71 Mn
Sep 30, 2024 -28.24 Mn
Jun 30, 2024 -21.44 Mn
Mar 31, 2024 -32.22 Mn
Dec 31, 2023 -37.43 Mn
Sep 30, 2023 -27.81 Mn
Jun 30, 2023 -37.57 Mn
Mar 31, 2023 -36.23 Mn
Dec 31, 2022 -38.29 Mn
Sep 30, 2022 -32.49 Mn
Jun 30, 2022 -27.38 Mn
Mar 31, 2022 -31.37 Mn
Dec 31, 2021 -15.26 Mn
Sep 30, 2021 -24.25 Mn
Jun 30, 2021 -22.12 Mn
Mar 31, 2021 -20.51 Mn
Dec 31, 2020 -18.90 Mn
Sep 30, 2020 -18.35 Mn
Jun 30, 2020 -10.86 Mn
Mar 31, 2020 -12.34 Mn
Dec 31, 2019 -10.50 Mn
Sep 30, 2019 -10.00 Mn