Growth Metrics

Alnylam Pharmaceuticals (ALNY) EBITDA Margin (2016 - 2025)

Alnylam Pharmaceuticals (ALNY) has disclosed EBITDA Margin for 15 consecutive years, with 6.82% as the latest value for Q4 2025.

  • For the quarter ending Q4 2025, EBITDA Margin rose 2257.0% year-over-year to 6.82%, compared with a TTM value of 9.0% through Dec 2025, up 2186.0%, and an annual FY2025 reading of 8.84%, up 2170.0% over the prior year.
  • EBITDA Margin was 6.82% for Q4 2025 at Alnylam Pharmaceuticals, down from 24.09% in the prior quarter.
  • Across five years, EBITDA Margin topped out at 24.09% in Q3 2025 and bottomed at 154.17% in Q3 2022.
  • Average EBITDA Margin over 5 years is 55.39%, with a median of 57.49% recorded in 2022.
  • The sharpest move saw EBITDA Margin surged 17449bps in 2023, then tumbled -5676bps in 2025.
  • Year by year, EBITDA Margin stood at 99.6% in 2021, then surged by 38bps to 62.19% in 2022, then surged by 53bps to 29.32% in 2023, then soared by 46bps to 15.76% in 2024, then soared by 143bps to 6.82% in 2025.
  • Business Quant data shows EBITDA Margin for ALNY at 6.82% in Q4 2025, 24.09% in Q3 2025, and 7.59% in Q2 2025.