Growth Metrics

Alnylam Pharmaceuticals (ALNY) EBITDA Margin (2016 - 2025)

Alnylam Pharmaceuticals' EBITDA Margin history spans 16 years, with the latest figure at 10.32% for Q4 2025.

  • For Q4 2025, EBITDA Margin rose 2608.0% year-over-year to 10.32%; the TTM value through Dec 2025 reached 9.29%, up 2215.0%, while the annual FY2025 figure was 8.84%, 2170.0% up from the prior year.
  • EBITDA Margin reached 10.32% in Q4 2025 per ALNY's latest filing, down from 20.76% in the prior quarter.
  • In the past five years, EBITDA Margin ranged from a high of 20.76% in Q3 2025 to a low of 154.17% in Q3 2022.
  • Average EBITDA Margin over 5 years is 55.38%, with a median of 57.49% recorded in 2022.
  • Peak YoY movement for EBITDA Margin: surged 17449bps in 2023, then tumbled -5676bps in 2025.
  • A 5-year view of EBITDA Margin shows it stood at 99.6% in 2021, then surged by 38bps to 62.19% in 2022, then surged by 53bps to 29.32% in 2023, then soared by 46bps to 15.76% in 2024, then skyrocketed by 166bps to 10.32% in 2025.
  • Per Business Quant, the three most recent readings for ALNY's EBITDA Margin are 10.32% (Q4 2025), 20.76% (Q3 2025), and 7.59% (Q2 2025).