Alnylam Pharmaceuticals (ALNY) EBITDA Margin (2009 - 2026)
Alnylam Pharmaceuticals' EBITDA Margin was 19.00% in Q2 2026, up 19.30 percentage points from -0.29% a year earlier but down 5.17 percentage points from the prior quarter.
Alnylam Pharmaceuticals (ALNY) EBITDA Margin (2009 - 2026) Analysis & Trends
On a trailing twelve-month basis, Alnylam Pharmaceuticals' EBITDA Margin was 21.95% through Jun 30, 2026, up 26.84 percentage points year-over-year; for FY2025, it was 15.00%, up 20.35 percentage points from FY2024.
- EBITDA Margin has now increased for seven consecutive years, with a five-year change of +176.04 percentage points (FY2020 to FY2025).
- In earlier years, EBITDA Margin was -5.35% in FY2024 (+7.13 pp), -12.48% in FY2023 (+58.91 pp), -71.39% in FY2022 (+6.91 pp) and -78.30% in FY2021 (+82.73 pp).
- Quarterly EBITDA Margin has moved between -93.62% (Q3 2022) and 30.57% (Q3 2025) over five years.
- Compared with a year earlier, EBITDA Margin was higher in four of the last six quarters, with an average year-over-year change of +7.72 percentage points.
- The best year-over-year quarter for EBITDA Margin over five years was Q3 2023 (a gain of 123.89 percentage points); the worst was Q3 2024 (a drop of 42.83 percentage points).
- Per Business Quant data, ALNY's EBITDA Margin in the three quarters before Q2 2026 was 24.18% (Q1 2026), 13.24% (Q4 2025) and 30.57% (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,348.13 Bn | 1,321.74 Bn | 20.46 Bn | 36.69% |
| 2 | Johnson & Johnson | 675.90 Bn | 595.76 Bn | 17.30 Bn | 32.68% |
| 3 | AbbVie | 519.45 Bn | 487.50 Bn | 13.12 Bn | 46.88% |
| 4 | Merck | 364.95 Bn | 327.95 Bn | 13.19 Bn | 40.60% |
| 5 | Novartis Ag | 311.58 Bn | 285.16 Bn | - | - |
| 6 | Astrazeneca | 289.34 Bn | 262.94 Bn | 13.26 Bn | 39.77% |
| 7 | Amgen | 251.64 Bn | 203.30 Bn | 7.58 Bn | 46.62% |
| 8 | Gilead Sciences | 212.05 Bn | 187.07 Bn | 6.73 Bn | 50.63% |
| 9 | Pfizer | 167.35 Bn | 115.00 Bn | 12.56 Bn | 42.49% |
| 10 | Alnylam Pharmaceuticals | 20.30 Bn | 7.49 Bn | 1.10 Bn | 24.71% |
Historic Data
| Date | Value |
|---|---|
| Sep 30, 2026 | 24.71% |
| Jun 30, 2026 | 19.00% |
| Mar 31, 2026 | 24.18% |
| Dec 31, 2025 | 13.24% |
| Sep 30, 2025 | 30.57% |
| Jun 30, 2025 | -0.29% |
| Dec 31, 2024 | -15.34% |
| Sep 30, 2024 | -12.56% |
| Jun 30, 2024 | 9.64% |
| Mar 31, 2024 | -6.05% |
| Dec 31, 2023 | -23.41% |
| Sep 30, 2023 | 30.27% |
| Jun 30, 2023 | -67.97% |
| Mar 31, 2023 | -42.51% |
| Dec 31, 2022 | -52.03% |
| Sep 30, 2022 | -93.62% |
| Jun 30, 2022 | -80.77% |
| Mar 31, 2022 | -64.37% |
| Dec 31, 2021 | -70.86% |
| Sep 30, 2021 | -90.54% |
Alnylam Pharmaceuticals EBITDA Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=ebitda-margin&ticker=ALNY&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "ebitda-margin", "ticker": "ALNY", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=ebitda-margin&ticker=ALNY&period=max&api_key=YOUR_API_KEY");
const data = await res.json();