C4 Therapeutics (CCCC) EBITDA Margin (2019 - 2026)
C4 Therapeutics (CCCC) posted EBITDA Margin of -393.48% for Q2 2026, up 37.99 percentage points from -431.47% a year earlier and up 51.59 percentage points from the prior quarter.
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C4 Therapeutics (CCCC) EBITDA Margin (2019 - 2026) Analysis & Trends
For the trailing twelve months through Jun 30, 2026, EBITDA Margin at C4 Therapeutics was -314.45%, up 40.76 percentage points year-over-year; for FY2025, it was -315.08%, up 15.95 percentage points from FY2024.
- Annual EBITDA Margin shows a five-year change of -137.85 percentage points (FY2020 to FY2025).
- In prior years, C4 Therapeutics' EBITDA Margin was -331.04% in FY2024 (+329.74 pp), -660.78% in FY2023 (-249.61 pp), -411.17% in FY2022 (-235.04 pp) and -176.13% in FY2021 (+1.10 pp).
- Quarterly EBITDA Margin has run from a low of -1393.02% in Q2 2023 to a high of -74.37% in Q4 2021 over five years.
- On a year-over-year basis, EBITDA Margin increased in five of the last eight quarters, with an average year-over-year change of +156.86 percentage points.
- The strongest year-over-year quarter for EBITDA Margin in the past five years was Q2 2024, with a gain of 1218.16 percentage points; the weakest was Q4 2022, with a drop of 1249.11 percentage points.
- According to Business Quant data, EBITDA Margin for the three prior quarters was -445.07% (Q1 2026), -206.22% (Q4 2025) and -302.33% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 35.95% |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 49.01% |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | 6.02% |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | - |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 33.11% |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 46.01% |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | -124.26% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 39.16% |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 39.10% |
| 10 | C4 Therapeutics | 383.47 Mn | -546.29 Mn | - | -393.48% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -393.48% |
| Mar 31, 2026 | -445.07% |
| Dec 31, 2025 | -206.22% |
| Sep 30, 2025 | -302.33% |
| Jun 30, 2025 | -431.47% |
| Mar 31, 2025 | -396.63% |
| Dec 31, 2024 | -719.12% |
| Sep 30, 2024 | -180.98% |
| Jun 30, 2024 | -174.86% |
| Mar 31, 2024 | -1,045.44% |
| Dec 31, 2023 | -1,134.53% |
| Sep 30, 2023 | -247.12% |
| Jun 30, 2023 | -1,393.02% |
| Mar 31, 2023 | -949.27% |
| Dec 31, 2022 | -1,323.48% |
| Sep 30, 2022 | -474.87% |
| Jun 30, 2022 | -194.80% |
| Mar 31, 2022 | -405.85% |
| Dec 31, 2021 | -74.37% |
| Sep 30, 2021 | -281.46% |
API Access
C4 Therapeutics EBITDA Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=ebitda-margin&ticker=CCCC&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "ebitda-margin", "ticker": "CCCC", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=ebitda-margin&ticker=CCCC&period=max&api_key=YOUR_API_KEY");
const data = await res.json();