C4 Therapeutics (CCCC) EBITDA (2019 - 2026)

C4 Therapeutics' (CCCC) quarterly EBITDA came in at -$27.8 million in Q1 2026, up 4.73% year-on-year from -$26.5 million in Q1 2025, and down 20.05% quarter-over-quarter from -$23.1 million in Q4 2025.

C4 Therapeutics (CCCC) EBITDA (2019 - 2026) Analysis & Trends

C4 Therapeutics' EBITDA history runs 8 years deep, the most recent figure standing at -$27.8 million for Q1 2026.

  • On a quarterly basis, EBITDA rose 4.73% year-over-year to -$27.8 million in Q1 2026; TTM through Mar 2026 was -$113.8 million, a 2.33% increase from a year earlier, with the FY2025 full-year figure at -$115.2 million, up 3.67% from the prior year.
  • EBITDA fell to -$27.8 million in Q1 2026 per CCCC's latest filing, from -$23.1 million in the prior quarter.
  • Across five years, EBITDA topped out at -$21.4 million in Q2 2024 and bottomed at -$38.3 million in Q4 2022.
  • The 5-year median for EBITDA is -$31.4 million (2022), against an average of -$31.2 million.
  • Across the five-year window, EBITDA plunged 151.02% in 2022 and jumped 42.92% in 2024, its largest moves.
  • Year by year, EBITDA stood at -$38.3 million in 2022, then advanced by 2.26% to -$37.4 million in 2023, then decreased by 0.75% to -$37.7 million in 2024, then soared by 38.62% to -$23.1 million in 2025, then fell by 20.05% to -$27.8 million in 2026.
  • Per Business Quant, the three latest CCCC EBITDA figures stand at -$27.8 million (Q1 2026), -$23.1 million (Q4 2025), and -$34.4 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -27.75 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 249.90 Mn
4 NuCana 279.75 Bn 279.75 Bn - -3.72 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 1.14 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 642.90 Mn
7 Belite Bio 62.51 Bn 62.51 Bn - -32.68 Mn
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 493.00 Mn
9 Revolution Medicines 37.78 Bn 37.78 Bn - -445.22 Mn
10 C4 Therapeutics 460.17 Mn 224.50 Mn - -27.79 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -27.79 Mn
Dec 31, 2025 -23.15 Mn
Sep 30, 2025 -34.41 Mn
Jun 30, 2025 -28.50 Mn
Mar 31, 2025 -29.16 Mn
Dec 31, 2024 -37.71 Mn
Sep 30, 2024 -28.24 Mn
Jun 30, 2024 -21.44 Mn
Mar 31, 2024 -32.22 Mn
Dec 31, 2023 -37.43 Mn
Sep 30, 2023 -27.81 Mn
Jun 30, 2023 -37.57 Mn
Mar 31, 2023 -36.23 Mn
Dec 31, 2022 -38.29 Mn
Sep 30, 2022 -32.49 Mn
Jun 30, 2022 -27.38 Mn
Mar 31, 2022 -31.37 Mn
Dec 31, 2021 -15.26 Mn
Sep 30, 2021 -24.25 Mn
Jun 30, 2021 -22.12 Mn