Growth Metrics

C4 Therapeutics (CCCC) EBITDA (2019 - 2026)

C4 Therapeutics' quarterly EBITDA came in at -$25.5 million in Q1 2026, up 3.16% year-on-year from -$24.7 million in Q1 2025, and down 23.94% quarter-over-quarter from -$20.6 million in Q4 2025.

C4 Therapeutics has reported EBITDA for 8 years, with the latest figure at -$25.5 million in Q1 2026.

  • For the quarter ending Q1 2026, EBITDA rose 3.16% year-over-year to -$25.5 million; the trailing twelve-month figure through Mar 2026 stood at -$104.2 million (down 1.33% YoY), and the FY2025 full-year result was -$105.0 million, changed 0.13% from the prior year.
  • EBITDA for Q1 2026 stood at -$25.5 million, down from -$20.6 million in the prior quarter.
  • The five-year high for EBITDA was -$17.8 million in Q2 2024, with the low at -$35.9 million in Q4 2022.
  • Average EBITDA over 5 years is -$29.2 million, with a median of -$28.6 million recorded in 2024.
  • Year-over-year, EBITDA plunged 120.62% in 2022 and soared 49.54% in 2024.
  • Tracing CCCC's EBITDA over 5 years: stood at -$35.9 million in 2022, then increased by 5.39% to -$34.0 million in 2023, then slipped by 2.94% to -$35.0 million in 2024, then soared by 41.17% to -$20.6 million in 2025, then slipped by 23.94% to -$25.5 million in 2026.
  • The last three EBITDA figures came in at -$25.5 million (Q1 2026), -$20.6 million (Q4 2025), and -$32.0 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -13.63 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -19.70 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -14.44 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 1.14 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - -3.82 Mn
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 661.60 Mn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 201.19 Mn
10 C4 Therapeutics 561.03 Mn 325.36 Mn - -25.50 Mn

Historic Data

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DateValue
Mar 31, 2026 -25.50 Mn
Dec 31, 2025 -20.58 Mn
Sep 30, 2025 -32.05 Mn
Jun 30, 2025 -26.09 Mn
Mar 31, 2025 -26.33 Mn
Dec 31, 2024 -34.98 Mn
Sep 30, 2024 -23.77 Mn
Jun 30, 2024 -17.78 Mn
Mar 31, 2024 -28.61 Mn
Dec 31, 2023 -33.98 Mn
Sep 30, 2023 -26.17 Mn
Jun 30, 2023 -35.23 Mn
Mar 31, 2023 -33.11 Mn
Dec 31, 2022 -35.91 Mn
Sep 30, 2022 -32.79 Mn
Jun 30, 2022 -28.34 Mn
Mar 31, 2022 -34.50 Mn
Dec 31, 2021 -16.28 Mn
Sep 30, 2021 -24.77 Mn
Jun 30, 2021 -22.56 Mn
Mar 31, 2021 -21.08 Mn
Dec 31, 2020 -21.79 Mn
Sep 30, 2020 -21.83 Mn
Jun 30, 2020 -10.80 Mn
Mar 31, 2020 -11.91 Mn
Dec 31, 2019 -10.02 Mn
Sep 30, 2019 -10.09 Mn