C4 Therapeutics (CCCC) Net Margin (2019 - 2026)
C4 Therapeutics' quarterly Net Margin came in at 408.47% in Q1 2026, down 4480.0% year-on-year from 9.33% in Q1 2025, and down 120.95% quarter-over-quarter from 184.87% in Q4 2025.
C4 Therapeutics has reported Net Margin for 8 years, with the latest figure at 408.47% in Q1 2026.
- For the quarter ending Q1 2026, Net Margin fell 4480.0% year-over-year to 408.47%; the trailing twelve-month figure through Mar 2026 stood at 297.41% (down 3781.0% YoY), and the FY2025 full-year result was 292.08%, up 388.0% from the prior year.
- Net Margin for Q1 2026 stood at 408.47%, down from 184.87% in the prior quarter.
- The five-year high for Net Margin was 147.56% in Q2 2024, with the low at 1348.42% in Q2 2023.
- Average Net Margin over 5 years is 560.14%, with a median of 408.47% recorded in 2026.
- Year-over-year, Net Margin plunged 122492 bps in 2022 and jumped 120086 bps in 2024.
- Tracing CCCC's Net Margin over 5 years: stood at 1302.91% in 2022, then rose by 18 bps to 1065.84% in 2023, then surged by 37 bps to 667.82% in 2024, then jumped by 72 bps to 184.87% in 2025, then sank by 121 bps to 408.47% in 2026.
- The last three Net Margin figures came in at 408.47% (Q1 2026), 184.87% (Q4 2025), and 286.43% (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 961,148.99 Bn | 961,148.98 Bn | - | - |
| 2 | Alterity Therapeutics | 744,933.29 Bn | 744,933.26 Bn | - | - |
| 3 | Legend Biotech | 2,540.00 Bn | 2,539.71 Bn | 242.10 Mn | 0.82% |
| 4 | Nanobiotix | 2,199.85 Bn | 2,199.78 Bn | - | - |
| 5 | Akari Therapeutics | 1,635.88 Bn | 1,635.88 Bn | - | - |
| 6 | Vertex Pharmaceuticals | 111.32 Bn | 104.07 Bn | 2.59 Bn | 34.53% |
| 7 | Evaxion A | 62.56 Bn | 62.54 Bn | - | - |
| 8 | Regeneron Pharmaceuticals | 62.55 Bn | 53.79 Bn | 3.31 Bn | 20.17% |
| 9 | Alnylam Pharmaceuticals | 39.57 Bn | 36.56 Bn | 959.66 Mn | 17.65% |
| 10 | C4 Therapeutics | 561.03 Mn | 325.36 Mn | - | -408.47% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -408.47% |
| Dec 31, 2025 | -184.87% |
| Sep 30, 2025 | -286.43% |
| Jun 30, 2025 | -402.60% |
| Mar 31, 2025 | -363.66% |
| Dec 31, 2024 | -667.82% |
| Sep 30, 2024 | -160.57% |
| Jun 30, 2024 | -147.56% |
| Mar 31, 2024 | -933.23% |
| Dec 31, 2023 | -1,065.84% |
| Sep 30, 2023 | -244.19% |
| Jun 30, 2023 | -1,348.42% |
| Mar 31, 2023 | -925.25% |
| Dec 31, 2022 | -1,302.91% |
| Sep 30, 2022 | -473.17% |
| Jun 30, 2022 | -194.29% |
| Mar 31, 2022 | -413.12% |
| Dec 31, 2021 | -77.99% |
| Sep 30, 2021 | -290.39% |
| Jun 30, 2021 | -230.86% |
| Mar 31, 2021 | -282.40% |
| Dec 31, 2020 | -138.37% |
| Sep 30, 2020 | -320.20% |
| Jun 30, 2020 | -141.69% |
| Mar 31, 2020 | -205.74% |
| Dec 31, 2019 | -122.10% |
| Sep 30, 2019 | -188.18% |