C4 Therapeutics (CCCC) Net Margin (2019 - 2026)
C4 Therapeutics (CCCC) recorded Net Margin of -355.90% in Q2 2026, up 46.70 percentage points from -402.60% a year earlier and up 52.57 percentage points from the prior quarter.
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Analysis
C4 Therapeutics (CCCC) Net Margin (2019 - 2026) Analysis & Trends
On a TTM basis, C4 Therapeutics' Net Margin came in at -289.45% as of Jun 30, 2026, up 36.42 percentage points year-over-year; for FY2025, it came in at -292.10%, up 3.87 percentage points from FY2024.
- Annual Net Margin has a five-year change of -92.26 percentage points (FY2020 to FY2025).
- Across earlier years, Net Margin came in at -295.96% in FY2024 (+342.41 pp), -638.37% in FY2023 (-226.10 pp), -412.27% in FY2022 (-229.04 pp) and -183.23% in FY2021 (+16.60 pp).
- Quarterly Net Margin has ranged from -1348.42% in Q2 2023 to -77.99% in Q4 2021 over the past five years.
- On a year-over-year basis, Net Margin rose in five of the last eight quarters, with an average year-over-year change of +144.27 percentage points.
- Peak year-over-year performance for Net Margin in the last five years was a gain of 1200.86 percentage points in Q2 2024, against a drop of 1225.80 percentage points in Q4 2022 at the low end.
- Per Business Quant, the preceding three quarters came in at -408.47% (Q1 2026), -186.02% (Q4 2025) and -286.43% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 21.86% |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 21.27% |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | -8.04% |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | 22.61% |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 18.81% |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 23.62% |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | -134.51% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | -1.65% |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 32.99% |
| 10 | C4 Therapeutics | 383.47 Mn | -546.29 Mn | - | -355.90% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -355.90% |
| Mar 31, 2026 | -408.47% |
| Dec 31, 2025 | -186.02% |
| Sep 30, 2025 | -286.43% |
| Jun 30, 2025 | -402.60% |
| Mar 31, 2025 | -363.66% |
| Dec 31, 2024 | -667.82% |
| Sep 30, 2024 | -160.57% |
| Jun 30, 2024 | -147.56% |
| Mar 31, 2024 | -933.23% |
| Dec 31, 2023 | -1,065.96% |
| Sep 30, 2023 | -244.19% |
| Jun 30, 2023 | -1,348.42% |
| Mar 31, 2023 | -925.25% |
| Dec 31, 2022 | -1,303.78% |
| Sep 30, 2022 | -473.17% |
| Jun 30, 2022 | -198.15% |
| Mar 31, 2022 | -413.12% |
| Dec 31, 2021 | -77.99% |
| Sep 30, 2021 | -290.39% |
API Access
C4 Therapeutics Net Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=net-margin&ticker=CCCC&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "net-margin", "ticker": "CCCC", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=net-margin&ticker=CCCC&period=max&api_key=YOUR_API_KEY");
const data = await res.json();