Vertex Pharmaceuticals (VRTX) EBITDA Margin (2009 - 2026)

Vertex Pharmaceuticals (VRTX) posted quarterly EBITDA Margin of 38.1% for Q1 2026, up 1536.0% year-over-year from 2.33% in Q1 2025, and up 0.8% on a QoQ basis from 37.8% in Q4 2025.

Vertex Pharmaceuticals (VRTX) EBITDA Margin (2009 - 2026) Analysis & Trends

Vertex Pharmaceuticals (VRTX) has reported EBITDA Margin for 18 consecutive years, with 38.1% the latest figure, recorded in Q1 2026.

  • In Q1 2026, EBITDA Margin rose 1536.0% year-over-year to 38.1%; the TTM figure through Mar 2026 stood at 38.31% (up 4500.0% YoY), while the FY2025 annual figure was 34.77%, up 3689.0% from the prior year.
  • EBITDA Margin came in at 38.1% for Q1 2026 at Vertex Pharmaceuticals, up from 37.8% in the prior quarter.
  • The five-year high for EBITDA Margin was 50.37% in Q2 2022, with the low at 132.85% in Q2 2024.
  • Average EBITDA Margin over 5 years is 29.95%, with a median of 39.26% recorded in 2023.
  • Across the five-year window, EBITDA Margin tumbled 17402 bps in 2024 and jumped 17168 bps in 2025, its largest moves.
  • Year by year, EBITDA Margin stood at 44.88% in 2022, then fell by 13 bps to 39.26% in 2023, then fell by 10 bps to 35.23% in 2024, then grew by 7 bps to 37.8% in 2025, then advanced by 1 bps to 38.1% in 2026.
  • According to Business Quant data, EBITDA Margin over the past three periods registered 38.1%, 37.8%, and 38.56% for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA Margin (Qtr)
1 Genmab A 276,399.99 Bn 276,398.47 Bn 831.00 Mn -11.83%
2 Akari Therapeutics 1,217.26 Bn 1,217.26 Bn - -
3 BeOne Medicines 419.38 Bn 414.59 Bn 1.35 Bn 16.51%
4 Vertex Pharmaceuticals 126.54 Bn 119.30 Bn 2.59 Bn 38.10%
5 Pharming 110.17 Bn 110.12 Bn 65.80 Mn -6.78%
6 Regeneron Pharmaceuticals 64.97 Bn 56.22 Bn 3.31 Bn 18.35%
7 Argenx Se 56.44 Bn 56.44 Bn 1.18 Bn 30.35%
8 Alnylam Pharmaceuticals 40.09 Bn 37.08 Bn 959.66 Mn 17.24%
9 Revolution Medicines 37.15 Bn 37.15 Bn - -
10 Moderna 28.64 Bn 23.43 Bn -566.00 Mn -356.81%

Historic Data

Download Data
DateValue
Mar 31, 2026 38.10%
Dec 31, 2025 37.80%
Sep 30, 2025 38.56%
Jun 30, 2025 38.83%
Mar 31, 2025 22.75%
Dec 31, 2024 35.23%
Sep 30, 2024 40.27%
Jun 30, 2024 -132.85%
Mar 31, 2024 42.35%
Dec 31, 2023 39.26%
Sep 30, 2023 41.80%
Jun 30, 2023 41.17%
Mar 31, 2023 32.80%
Dec 31, 2022 44.88%
Sep 30, 2022 48.27%
Jun 30, 2022 50.37%
Mar 31, 2022 49.63%
Dec 31, 2021 42.35%
Sep 30, 2021 53.15%
Jun 30, 2021 -2.11%