Vertex Pharmaceuticals (VRTX) EBITDA Margin (2009 - 2026)
Vertex Pharmaceuticals' EBITDA Margin was 39.10% in Q2 2026, down 1.48 percentage points from 40.57% a year earlier and down 0.88 percentage points from the prior quarter.
Vertex Pharmaceuticals (VRTX) EBITDA Margin (2009 - 2026) Analysis & Trends
On a trailing twelve-month basis, Vertex Pharmaceuticals' EBITDA Margin was 39.72% through Jun 30, 2026, up 3.61 percentage points year-over-year; for FY2025, it was 36.52%, up 36.76 percentage points from FY2024.
- EBITDA Margin shows a five-year change of -11.27 percentage points (FY2020 to FY2025).
- In earlier years, EBITDA Margin was -0.23% in FY2024 (-40.90 pp), 40.66% in FY2023 (-9.23 pp), 49.89% in FY2022 (+11.50 pp) and 38.39% in FY2021 (-9.40 pp).
- The Q2 2026 figure marks the lowest quarterly EBITDA Margin since Q1 2025.
- Compared with a year earlier, EBITDA Margin was higher in three of the last eight quarters, with an average year-over-year change of +20.04 percentage points.
- The best year-over-year quarter for EBITDA Margin over five years was Q2 2025 (a gain of 171.38 percentage points); the worst was Q2 2024 (a drop of 173.64 percentage points).
- Per Business Quant data, VRTX's EBITDA Margin in the three quarters before Q2 2026 was 39.97% (Q1 2026), 39.55% (Q4 2025) and 40.31% (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,221.09 Bn | 1,194.71 Bn | 20.46 Bn | 54.65% |
| 2 | Johnson & Johnson | 656.38 Bn | 576.24 Bn | 17.30 Bn | 32.68% |
| 3 | AbbVie | 510.79 Bn | 478.80 Bn | 13.12 Bn | 46.88% |
| 4 | Merck | 363.00 Bn | 317.38 Bn | 12.21 Bn | 6.02% |
| 5 | Novartis Ag | 313.89 Bn | 287.12 Bn | - | - |
| 6 | Astrazeneca | 290.02 Bn | 263.91 Bn | 13.26 Bn | 39.77% |
| 7 | Amgen | 249.59 Bn | 204.98 Bn | 7.24 Bn | 46.01% |
| 8 | Gilead Sciences | 208.15 Bn | 183.26 Bn | 6.73 Bn | 50.63% |
| 9 | Pfizer | 170.74 Bn | 118.10 Bn | 12.56 Bn | 42.49% |
| 10 | Vertex Pharmaceuticals | 137.20 Bn | 109.19 Bn | 2.91 Bn | 22.73% |
Historic Data
| Date | Value |
|---|---|
| Sep 30, 2026 | 22.73% |
| Jun 30, 2026 | 39.10% |
| Mar 31, 2026 | 39.97% |
| Dec 31, 2025 | 39.55% |
| Sep 30, 2025 | 40.31% |
| Jun 30, 2025 | 40.57% |
| Mar 31, 2025 | 24.49% |
| Dec 31, 2024 | 36.83% |
| Sep 30, 2024 | 42.19% |
| Jun 30, 2024 | -130.81% |
| Mar 31, 2024 | 44.34% |
| Dec 31, 2023 | 41.61% |
| Sep 30, 2023 | 43.50% |
| Jun 30, 2023 | 42.83% |
| Mar 31, 2023 | 34.44% |
| Dec 31, 2022 | 46.55% |
| Sep 30, 2022 | 49.84% |
| Jun 30, 2022 | 52.07% |
| Mar 31, 2022 | 51.34% |
| Dec 31, 2021 | 43.98% |
Vertex Pharmaceuticals EBITDA Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=ebitda-margin&ticker=VRTX&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "ebitda-margin", "ticker": "VRTX", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=ebitda-margin&ticker=VRTX&period=max&api_key=YOUR_API_KEY");
const data = await res.json();