Vertex Pharmaceuticals VRTX
NASDAQ VRTX
$522.38 +6.04 (+1.17%)
At close: Sep 24, 2026 · 4:00 PM EDT

Vertex Pharmaceuticals (VRTX) EBITDA Margin (2009 - 2026)

Vertex Pharmaceuticals (VRTX) posted EBITDA Margin of 37.4% for Q2 2026, down 1.84% on a QoQ basis from 38.1% in Q1 2026, and down 143.0% year-over-year from 86.98% in Q2 2025.

Analysis

Vertex Pharmaceuticals (VRTX) EBITDA Margin (2009 - 2026) Analysis & Trends

Vertex Pharmaceuticals has reported EBITDA Margin for 18 years, with the latest figure at 37.4% in Q2 2026.

  • On a quarterly basis, EBITDA Margin fell 143.0% year-over-year to 37.4% in Q2 2026; TTM through Jun 2026 was 37.95%, a 359.0% increase from a year earlier, with the FY2025 full-year figure at 34.77%, up 3689.0% from the prior year.
  • EBITDA Margin was 37.4% for Q2 2026 at Vertex Pharmaceuticals, down from 38.1% in the prior quarter.
  • The five-year high for EBITDA Margin was 50.37% in Q2 2022, with the low at 132.85% in Q2 2024.
  • Average EBITDA Margin over 5 years is 30.37%, with a median of 39.04% recorded in 2023.
  • The sharpest annual moves came in 2024 and 2025: EBITDA Margin sank 17402 bps in 2024, then surged 17168 bps in 2025.
  • Over 5 years, EBITDA Margin stood at 44.88% in 2022, then dropped by 13 bps to 39.26% in 2023, then dropped by 10 bps to 35.23% in 2024, then advanced by 7 bps to 37.8% in 2025, then slipped by 1 bps to 37.4% in 2026.
  • The last three EBITDA Margin figures came in at 37.4% (Q2 2026), 38.1% (Q1 2026), and 37.8% (Q4 2025), per Business Quant data.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA Margin (Qtr)
1 Johnson & Johnson 649.01 Bn 628.25 Bn 17.26 Bn 28.21%
2 AbbVie 468.55 Bn 462.03 Bn 12.70 Bn 37.86%
3 Merck 365.49 Bn 358.40 Bn 12.21 Bn -3.52%
4 Novartis Ag 272.39 Bn 265.10 Bn 11.24 Bn 32.97%
5 Astrazeneca 253.18 Bn 247.96 Bn 12.86 Bn 20.57%
6 Amgen 219.53 Bn 205.54 Bn 7.24 Bn 34.95%
7 Gilead Sciences 187.85 Bn 184.59 Bn 6.22 Bn -133.21%
8 Pfizer 160.56 Bn 149.16 Bn 10.94 Bn 28.37%
9 Vertex Pharmaceuticals 130.81 Bn 122.96 Bn 2.84 Bn 37.40%
10 Bristol Myers Squibb 124.95 Bn 113.89 Bn 9.25 Bn 2.77%
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 37.40%
Mar 31, 2026 38.10%
Dec 31, 2025 37.80%
Sep 30, 2025 38.56%
Jun 30, 2025 38.83%
Mar 31, 2025 22.75%
Dec 31, 2024 35.23%
Sep 30, 2024 40.27%
Jun 30, 2024 -132.85%
Mar 31, 2024 42.35%
Dec 31, 2023 39.26%
Sep 30, 2023 41.80%
Jun 30, 2023 41.17%
Mar 31, 2023 32.80%
Dec 31, 2022 44.88%
Sep 30, 2022 48.27%
Jun 30, 2022 50.37%
Mar 31, 2022 49.63%
Dec 31, 2021 42.35%
Sep 30, 2021 53.15%
API Access

Vertex Pharmaceuticals EBITDA Margin API

Pull this series into your own models, spreadsheets and apps with the Business Quant Historical Metrics API. The request below matches the chart above — change the frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.

https://data.businessquant.com/historic?slug=ebitda-margin&ticker=VRTX&period=max&api_key=YOUR_API_KEY