C4 Therapeutics, Inc. (CCCC) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

72,563,311Shares Outstanding

80,928,364Shares held by institutions

$252,496,496Value of institutional holdings

111.53%Institutional ownership %

54.15%Shares Changed QoQ

100No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

C4 Therapeutics, Inc. (NASDAQ:CCCC) showed up in the 13F filings of 100 institutional investors as of December 2025.

These investors held 110.0% of outstanding shares in December 2025, up from 75.1% in September 2025.
They increased total shares held in CCCC by 52.88% quarter over quarter, and investors in C4 Therapeutics decreased 11.5% from a year ago.
Among the 100 funds, 66 bought more C4 Therapeutics shares, 23 sold down, and 11 held their ground.
Altogether, these fund groups held 79.83Mn shares in CCCC by December 2025, up by 27.61Mn shares quarter on quarter, and up 11.42Mn shares year over year.
Point72 Asset Management, L.P. is the top holder of C4 Therapeutics as of December 31, 2025, with 9.44Mn shares representing 13.01% of outstanding stock.
Top purchasers of CCCC stock for the quarter ending December 2025 included Point72 Asset Management, L.P. (9.44Mn), RA CAPITAL MANAGEMENT, L.P. (8.0Mn), Bain Capital Life Sciences Investors, LLC (6.06Mn), Morgan Stanley (4.01Mn), Goldman Sachs Group Inc (1.72Mn).
Top sellers of CCCC stock for the quarter ending December 2025 included ORBIMED ADVISORS LLC (3.83Mn), Soleus Capital Management, L.P. (3.25Mn), Bank Of America Corp /De/ (1.72Mn), MILLENNIUM MANAGEMENT LLC (745.26K), WASATCH ADVISORS LP (507.82K).
Business Quant data shows the 10 biggest positions in C4 Therapeutics as of December 2025 are held by Point72 Asset Management, L.P. (9.44Mn), Morgan Stanley (8.98Mn), RA CAPITAL MANAGEMENT, L.P. (8.0Mn), Bain Capital Life Sciences Investors, LLC (7.17Mn), Lynx1 Capital Management LP (7.1Mn), VANGUARD GROUP INC (4.38Mn), WASATCH ADVISORS LP (4.34Mn), Soleus Capital Management, L.P. (3.8Mn), Bank Of America Corp /De/ (2.39Mn), Goldman Sachs Group Inc (2.18Mn).

100 Institutional Holders

80,928,364 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
Point72 Asset Management, L.P.	31 Dec, 2025	9,439,328	9,439,328	0.00%	$18,029,116.00
Morgan Stanley	31 Dec, 2025	8,981,662	4,009,630	80.64%	$17,154,974.00
RA CAPITAL MANAGEMENT, L.P.	31 Dec, 2025	8,000,000	8,000,000	0.00%	$15,280,000.00
Bain Capital Life Sciences Investors, LLC	31 Dec, 2025	7,171,910	6,060,000	545.01%	$13,698,348.00
Lynx1 Capital Management LP	31 Dec, 2025	7,098,133	0	0.00%	$13,557,434.00
VANGUARD GROUP INC	31 Dec, 2025	4,379,815	1,188,258	37.23%	$8,365,446.00
WASATCH ADVISORS LP	31 Dec, 2025	4,344,918	-507,823	-10.46%	$8,298,793.00
Soleus Capital Management, L.P.	31 Dec, 2025	3,803,942	-3,250,000	-46.07%	$7,265,529.00
Bank Of America Corp /De/	31 Dec, 2025	2,387,586	-1,718,738	-41.86%	$4,560,290.00
Goldman Sachs Group Inc	31 Dec, 2025	2,178,040	1,718,147	373.60%	$4,160,056.00
SILVERARC CAPITAL MANAGEMENT, LLC	31 Dec, 2025	1,994,224	96,841	5.10%	$3,808,968.00
BlackRock, Inc.	31 Dec, 2025	1,969,814	374,175	23.45%	$3,762,346.00
SUSQUEHANNA INTERNATIONAL GROUP, LLP	31 Dec, 2025	1,775,783	1,260,346	244.52%	$3,391,746.00
RENAISSANCE TECHNOLOGIES LLC	31 Dec, 2025	1,602,580	665,630	71.04%	$3,060,928.00
TWO SIGMA INVESTMENTS, LP	31 Dec, 2025	1,509,603	674,877	80.85%	$2,883,342.00
ORBIMED ADVISORS LLC	31 Dec, 2025	1,404,902	-3,830,244	-73.16%	$2,683,363.00
MILLENNIUM MANAGEMENT LLC	31 Dec, 2025	1,188,969	-745,256	-38.53%	$2,270,931.00
TWO SIGMA ADVISERS, LP	31 Dec, 2025	1,068,200	305,100	39.98%	$2,040,262.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	988,878	263,574	36.34%	$1,889,264.00
JANE STREET GROUP, LLC	31 Dec, 2025	874,794	671,226	329.73%	$1,670,856.00

1 - 20 of 100

Research Tools