C4 Therapeutics, Inc. (CCCC) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

0Shares Outstanding

23,075,186Shares held by institutions

$54,226,687Value of institutional holdings

71.11%Institutional ownership %

-10.18%Shares Changed QoQ

101No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

C4 Therapeutics, Inc. (NASDAQ:CCCC) is held by 100 institutional investors per 13F filings through December 2025.

Their combined ownership stood at 110.0% of outstanding shares in December 2025, up from 75.1% in September 2025.
They increased total shares held in CCCC by 52.88% quarter over quarter, and investors in C4 Therapeutics decreased 11.5% from a year ago.
Activity in CCCC broke down as 66 buyers, 23 sellers, and 11 unchanged among 100 total holders.
In total, institutional investors held 79.83Mn shares in C4 Therapeutics as of December 2025, up by 27.61Mn shares quarter on quarter, and up 11.42Mn shares year over year.
Point72 Asset Management, L.P. holds the largest position in CCCC at 9.44Mn shares as of December 31, 2025, or 13.01% of shares outstanding.
The largest buyers of C4 Therapeutics for the quarter ending December 2025 were Point72 Asset Management, L.P. (9.44Mn), RA CAPITAL MANAGEMENT, L.P. (8.0Mn), Bain Capital Life Sciences Investors, LLC (6.06Mn), Morgan Stanley (4.01Mn), SUSQUEHANNA INTERNATIONAL GROUP, LLP (1.26Mn).
The largest sales of CCCC for the quarter ending December 2025 came from ORBIMED ADVISORS LLC (3.83Mn), Soleus Capital Management, L.P. (3.25Mn), Bank Of America Corp /De/ (1.72Mn), MILLENNIUM MANAGEMENT LLC (745.26K), WASATCH ADVISORS LP (507.82K).
Business Quant data shows the 10 biggest positions in C4 Therapeutics as of December 2025 are held by Point72 Asset Management, L.P. (9.44Mn), Morgan Stanley (8.98Mn), RA CAPITAL MANAGEMENT, L.P. (8.0Mn), Bain Capital Life Sciences Investors, LLC (7.17Mn), Lynx1 Capital Management LP (7.1Mn), VANGUARD GROUP INC (4.38Mn), WASATCH ADVISORS LP (4.34Mn), Soleus Capital Management, L.P. (3.8Mn), Bank Of America Corp /De/ (2.39Mn), SILVERARC CAPITAL MANAGEMENT, LLC (1.99Mn).

100 Institutional Holders

23,075,186 Total Shares Held

Rows:

Download Data

Owner Name	Date	Change (QoQ)	Change (%)	Value (USD)
BlackRock, Inc.	31 Dec, 2025	374,175	23.45%	$0.00
Morgan Stanley	31 Dec, 2025	4,009,630	80.64%	$0.00
Point72 Asset Management, L.P.	31 Dec, 2025	9,439,328	0.00%	$0.00
Barclays Plc	31 Dec, 2025	-67,315	-23.49%	$0.00
RA CAPITAL MANAGEMENT, L.P.	31 Dec, 2025	8,000,000	0.00%	$0.00
Bain Capital Life Sciences Investors, LLC	31 Dec, 2025	6,060,000	545.01%	$0.00
HSBC HOLDINGS PLC	31 Dec, 2025	13,629	100.00%	$0.00
VANGUARD GROUP INC	31 Dec, 2025	1,188,258	37.23%	$0.00
Lynx1 Capital Management LP	31 Dec, 2025	0	0.00%	$0.00
WASATCH ADVISORS LP	31 Dec, 2025	-507,823	-10.46%	$0.00
Soleus Capital Management, L.P.	31 Dec, 2025	-3,250,000	-46.07%	$0.00
Bank Of America Corp /De/	31 Dec, 2025	-1,718,738	-41.86%	$0.00
SILVERARC CAPITAL MANAGEMENT, LLC	31 Dec, 2025	96,841	5.10%	$0.00
SUSQUEHANNA INTERNATIONAL GROUP, LLP	31 Dec, 2025	1,260,346	244.52%	$0.00
Walleye Capital LLC	31 Dec, 2025	443,341	0.00%	$0.00
RENAISSANCE TECHNOLOGIES LLC	31 Dec, 2025	665,630	71.04%	$0.00
Qube Research & Technologies Ltd	31 Dec, 2025	174,261	150.26%	$0.00
TWO SIGMA INVESTMENTS, LP	31 Dec, 2025	674,877	80.85%	$0.00
Susquehanna Portfolio Strategies, LLC	31 Dec, 2025	0	0.00%	$0.00
ORBIMED ADVISORS LLC	31 Dec, 2025	-3,830,244	-73.16%	$0.00

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