Legend Biotech (LEGN) EBITDA Margin (2019 - 2025)

Legend Biotech (LEGN) posted EBITDA Margin of 6.43% for Q4 2025, down 143.18% quarter-over-quarter from 14.9% in Q3 2025, and up 3609.0% year-on-year from 0.17% in Q4 2024.

Legend Biotech (LEGN) EBITDA Margin (2019 - 2025) Analysis & Trends

Legend Biotech (LEGN) has reported EBITDA Margin for 7 consecutive years, with 6.43% the latest figure, recorded in Q4 2025.

  • EBITDA Margin for Q4 2025 came in at 6.43%, up 3609.0% year-over-year; the trailing twelve-month figure through Dec 2025 was 8.05% (up 1365.0% YoY), and the FY2025 annual result was 13.27%, up 3607.0% from the prior year.
  • EBITDA Margin was 6.43% for Q4 2025 at Legend Biotech, down from 14.9% in the prior quarter.
  • Over five years, EBITDA Margin peaked at 395.35% in Q4 2022 and troughed at 1150.03% in Q3 2022.
  • Average EBITDA Margin over 5 years is 131.28%, with a median of 2.54% recorded in 2022.
  • Year-over-year, EBITDA Margin plunged 137590 bps in 2021 and jumped 106416 bps in 2023.
  • Over 5 years, EBITDA Margin stood at 230.36% in 2021, then surged by 72 bps to 395.35% in 2022, then tumbled by 85 bps to 57.62% in 2023, then sank by 174 bps to 42.52% in 2024, then soared by 85 bps to 6.43% in 2025.
  • Per Business Quant data, the three most recent EBITDA Margin figures were 6.43% in Q4 2025, 14.9% in Q3 2025, and 0.46% in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA Margin (Qtr)
1 Genmab A 276,399.99 Bn 276,398.47 Bn 831.00 Mn -11.83%
2 Akari Therapeutics 1,217.26 Bn 1,217.26 Bn - -
3 BeOne Medicines 419.38 Bn 414.59 Bn 1.35 Bn 16.51%
4 Vertex Pharmaceuticals 126.54 Bn 119.30 Bn 2.59 Bn 38.10%
5 Pharming 110.17 Bn 110.12 Bn 65.80 Mn -6.78%
6 Regeneron Pharmaceuticals 64.97 Bn 56.22 Bn 3.31 Bn 18.35%
7 Argenx Se 56.44 Bn 56.44 Bn 1.18 Bn 30.35%
8 Alnylam Pharmaceuticals 40.09 Bn 37.08 Bn 959.66 Mn 17.24%
9 Revolution Medicines 37.15 Bn 37.15 Bn - -
10 Legend Biotech 11.04 Bn 10.14 Bn 242.10 Mn -6.43%

Historic Data

Download Data
DateValue
Dec 31, 2025 -6.43%
Sep 30, 2025 14.90%
Jun 30, 2025 0.46%
Mar 31, 2025 31.13%
Dec 31, 2024 -42.52%
Sep 30, 2024 39.59%
Jun 30, 2024 15.40%
Mar 31, 2024 -51.06%
Dec 31, 2023 57.62%
Sep 30, 2023 -85.87%
Jun 30, 2023 -281.06%
Mar 31, 2023 -271.34%
Dec 31, 2022 395.35%
Sep 30, 2022 -1,150.03%
Jun 30, 2022 25.22%
Mar 31, 2022 4.62%
Dec 31, 2021 230.36%
Sep 30, 2021 -726.03%
Jun 30, 2021 -857.64%
Mar 31, 2021 31.79%