Intellia Therapeutics (NTLA) Operating Margin (2015 - 2026)

Intellia Therapeutics (NTLA) posted quarterly Operating Margin of 668.08% for Q1 2026, up 5850.0% year-over-year from 11.23% in Q1 2025, and down 55.78% quarter-over-quarter from 428.86% in Q4 2025.

Intellia Therapeutics (NTLA) Operating Margin (2015 - 2026) Analysis & Trends

Intellia Therapeutics (NTLA) has reported Operating Margin for 12 consecutive years, with 668.08% the latest figure, recorded in Q1 2026.

  • In Q1 2026, Operating Margin rose 5850.0% year-over-year to 668.08%; the TTM figure through Mar 2026 stood at 636.56% (up 55080.0% YoY), while the FY2025 annual figure was 651.67%, up 27143.0% from the prior year.
  • Operating Margin eased to 668.08% in Q1 2026 per NTLA's latest filing, from 428.86% in the prior quarter.
  • Across five years, Operating Margin topped out at 7297.44% in Q4 2023 and bottomed at 1998.61% in Q2 2024.
  • Historically, Operating Margin has averaged 452.5% across 5 years, with a median of 808.86% in 2025.
  • Annual changes were most pronounced in 2023 — Operating Margin soared 810852 bps — and 2024, when it tumbled 835731 bps.
  • Intellia Therapeutics' Operating Margin stood at 811.07% in 2022, then surged by 1000 bps to 7297.44% in 2023, then slumped by 115 bps to 1059.86% in 2024, then soared by 60 bps to 428.86% in 2025, then sank by 56 bps to 668.08% in 2026.
  • Business Quant data shows NTLA's Operating Margin at 668.08% in Q1 2026, 428.86% in Q4 2025, and 808.86% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Operating Margin (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 37.40%
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 30.15%
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 31.68%
4 Revolution Medicines 43.64 Bn 43.64 Bn - -
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 19.06%
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -105.20%
7 Royalty Pharma 33.72 Bn 35.84 Bn - 19.75%
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 17.93%
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -0.36%
10 Intellia Therapeutics 1.67 Bn 1.67 Bn - -1,472.25%

Historic Data

Download Data
DateValue
Jun 30, 2026 -1,472.25%
Mar 31, 2026 -668.08%
Dec 31, 2025 -428.86%
Sep 30, 2025 -808.86%
Jun 30, 2025 -772.17%
Mar 31, 2025 -726.57%
Dec 31, 2024 -1,059.86%
Sep 30, 2024 -1,588.96%
Jun 30, 2024 -1,998.61%
Mar 31, 2024 -394.00%
Dec 31, 2023 7,297.44%
Sep 30, 2023 -1,093.29%
Jun 30, 2023 -973.47%
Mar 31, 2023 -888.13%
Dec 31, 2022 -811.07%
Sep 30, 2022 -795.49%
Jun 30, 2022 -700.65%
Mar 31, 2022 -1,281.96%
Dec 31, 2021 -625.60%
Sep 30, 2021 -999.35%