Intellia Therapeutics, Inc. (NTLA) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

110,134,783Shares Outstanding

4,563,047Shares held by institutions

$55,760,434Value of institutional holdings

95.18%Institutional ownership %

6.88%Shares Changed QoQ

280No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Recent 13F filings as of December 2025 show that 280 institutional investors hold a position in Intellia Therapeutics, Inc. (NASDAQ:NTLA).

These investors collectively held 95.2% of the company's total shares outstanding in December 2025, down from 95.4% in September 2025.
The company experienced a 6.88% quarterly change in institutional shares held, alongside a decrease of 2.44% in total owners annually.
The latest 13F cycle for Intellia Therapeutics reveals that of 280 total investors, 158 funds grew their exposure, whereas 82 reduced theirs and 40 made no changes.
Collectively, institutional investors increased their stake in Intellia Therapeutics to 104.82Mn shares as of December 2025, a change that is up by 6.75Mn shares quarter on quarter and up 5.60Mn shares year over year.
As of December 31, 2025, ARK Investment Management LLC held Intellia Therapeutics's largest shareholding position with over 14.21Mn shares, representing 12.90% of total outstanding shares.
Among the most significant buyers of Intellia Therapeutics during December 2025 were D. E. Shaw & Co., Inc. (3.10Mn), ARK Investment Management LLC (2.29Mn), VANGUARD GROUP INC (1.97Mn), STATE STREET CORP (1.45Mn), RENAISSANCE TECHNOLOGIES LLC (1.02Mn).
Leading sellers of Intellia Therapeutics stock in December 2025 included Contrarius Group Holdings Ltd (5.18Mn), MORGAN STANLEY (3.69Mn), GOLDMAN SACHS GROUP INC (2.82Mn), MILLENNIUM MANAGEMENT LLC (481.14K), ROYAL BANK OF CANADA (425.15K).
The top 10 institutional holders of Intellia Therapeutics for the quarter ending December 2025 included ARK Investment Management LLC (14.21Mn), VANGUARD GROUP INC (13.01Mn), BlackRock, Inc. (10.28Mn), STATE STREET CORP (6.42Mn), D. E. Shaw & Co., Inc. (5.33Mn), REGENERON PHARMACEUTICALS, INC. (3.70Mn), TWO SIGMA INVESTMENTS, LP (2.70Mn), GEODE CAPITAL MANAGEMENT, LLC (2.70Mn), TWO SIGMA ADVISERS, LP (2.35Mn), MORGAN STANLEY (2.33Mn).

280 Institutional Holders

4,563,047 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
ARK Investment Management LLC	31 Dec, 2025	14,207,324	2,288,146	19.20%	$127,723,840.00
VANGUARD GROUP INC	31 Dec, 2025	13,010,001	1,965,181	17.79%	$116,959,909.00
BlackRock, Inc.	31 Dec, 2025	10,276,849	1,001,032	10.79%	$92,388,870.00
STATE STREET CORP	31 Dec, 2025	6,418,836	1,447,967	29.13%	$57,705,336.00
D. E. Shaw & Co., Inc.	31 Dec, 2025	5,331,064	3,102,664	139.23%	$47,926,266.00
REGENERON PHARMACEUTICALS, INC.	31 Dec, 2025	3,702,995	0	0.00%	$33,289,925.00
TWO SIGMA INVESTMENTS, LP	31 Dec, 2025	2,698,738	249,131	10.17%	$24,261,655.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	2,696,187	107,333	4.15%	$24,242,683.00
TWO SIGMA ADVISERS, LP	31 Dec, 2025	2,346,317	182,900	8.45%	$21,093,390.00
MORGAN STANLEY	31 Dec, 2025	2,327,852	-3,694,724	-61.35%	$20,927,396.00
Sumitomo Mitsui Trust Group, Inc.	31 Dec, 2025	2,192,461	-162,395	-6.90%	$19,710,224.00
Amova Asset Management Americas, Inc.	31 Dec, 2025	2,192,461	-162,395	-6.90%	$19,688,300.00
DIMENSIONAL FUND ADVISORS LP	31 Dec, 2025	1,931,849	174,555	9.93%	$17,367,448.00
FMR LLC	31 Dec, 2025	1,759,898	-92,394	-4.99%	$15,821,480.00
VOLORIDGE INVESTMENT MANAGEMENT, LLC	31 Dec, 2025	1,737,450	127,245	7.90%	$15,619,676.00
RENAISSANCE TECHNOLOGIES LLC	31 Dec, 2025	1,672,700	1,021,700	156.94%	$15,037,573.00
GOLDMAN SACHS GROUP INC	31 Dec, 2025	1,455,619	-2,823,058	-65.98%	$13,086,015.00
BANK OF AMERICA CORP /DE/	31 Dec, 2025	1,242,378	636,852	105.17%	$11,168,977.00
UBS Group AG	31 Dec, 2025	1,237,736	129,550	11.69%	$11,127,247.00
ARMISTICE CAPITAL, LLC	31 Dec, 2025	1,156,000	484,000	72.02%	$10,392,440.00

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