Twist Bioscience (TWST) Operating Margin (2017 - 2026)
Twist Bioscience's (TWST) quarterly Operating Margin came in at 30.65% in Q2 2026, up 71.0% year-over-year from 17.92% in Q2 2025, and up 26.01% quarter-over-quarter from 41.42% in Q1 2026.
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Twist Bioscience (TWST) Operating Margin (2017 - 2026) Analysis & Trends
Twist Bioscience (TWST) has reported Operating Margin for 10 consecutive years, with 30.65% the latest figure, recorded in Q2 2026.
- On a quarterly basis, Operating Margin rose 71.0% year-over-year to 30.65% in Q2 2026; TTM through Jun 2026 was 33.58%, a 572.0% increase from a year earlier, with the FY2025 full-year figure at 36.18%, up 3437.0% from the prior year.
- Operating Margin was 30.65% for Q2 2026 at Twist Bioscience, up from 41.42% in the prior quarter.
- Over five years, Operating Margin peaked at 30.23% in Q3 2025 and troughed at 126.34% in Q1 2022.
- A 5-year average of 67.84% and a median of 65.31% in 2023 frame the typical range for Operating Margin.
- Across the five-year window, Operating Margin tumbled 1380 bps in 2024 and surged 7780 bps in 2025, its largest moves.
- Over 5 years, Operating Margin stood at 82.28% in 2022, then advanced by 20 bps to 65.7% in 2023, then jumped by 41 bps to 39.05% in 2024, then increased by 19 bps to 31.73% in 2025, then climbed by 3 bps to 30.65% in 2026.
- The last three Operating Margin figures came in at 30.65% (Q2 2026), 41.42% (Q1 2026), and 31.73% (Q4 2025), per Business Quant data.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Thermo Fisher Scientific | 241.68 Bn | 237.61 Bn | 8.34 Bn | 17.40% |
| 2 | Danaher | 147.34 Bn | 142.99 Bn | 3.61 Bn | 17.99% |
| 3 | Agilent Technologies | 43.34 Bn | 41.59 Bn | 1.04 Bn | 23.64% |
| 4 | Illumina | 34.58 Bn | 33.41 Bn | 770.00 Mn | 21.14% |
| 5 | Revvity | 16.31 Bn | 15.29 Bn | 416.87 Mn | 12.24% |
| 6 | Bio-Techne | 11.28 Bn | 11.01 Bn | 211.39 Mn | 23.13% |
| 7 | Bio-Rad Laboratories | 10.16 Bn | 8.54 Bn | 345.80 Mn | 11.15% |
| 8 | Repligen | 9.77 Bn | 8.75 Bn | 110.04 Mn | 6.85% |
| 9 | 10x Genomics | 9.45 Bn | 8.90 Bn | 112.50 Mn | -12.95% |
| 10 | Twist Bioscience | 8.93 Bn | 8.76 Bn | 62.45 Mn | -30.65% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -30.65% |
| Mar 31, 2026 | -41.42% |
| Dec 31, 2025 | -31.73% |
| Sep 30, 2025 | -30.23% |
| Jun 30, 2025 | -31.36% |
| Mar 31, 2025 | -44.79% |
| Dec 31, 2024 | -39.05% |
| Sep 30, 2024 | -42.55% |
| Jun 30, 2024 | -109.15% |
| Mar 31, 2024 | -64.92% |
| Dec 31, 2023 | -65.70% |
| Sep 30, 2023 | -74.85% |
| Jun 30, 2023 | -95.36% |
| Mar 31, 2023 | -102.42% |
| Dec 31, 2022 | -82.28% |
| Sep 30, 2022 | -99.24% |
| Jun 30, 2022 | -109.00% |
| Mar 31, 2022 | -126.34% |
| Dec 31, 2021 | -133.13% |
| Sep 30, 2021 | -104.90% |