Twist Bioscience (TWST) Net Margin (2017 - 2026)

Twist Bioscience (TWST) posted quarterly Net Margin of 39.76% for Q1 2026, up 262.0% year-over-year from 10.98% in Q1 2025, and down 35.15% quarter-over-quarter from 29.42% in Q4 2025.

Twist Bioscience (TWST) Net Margin (2017 - 2026) Analysis & Trends

Twist Bioscience (TWST) has reported Net Margin for 10 consecutive years, with 39.76% the latest figure, recorded in Q1 2026.

  • In Q1 2026, Net Margin rose 262.0% year-over-year to 39.76%; the TTM figure through Mar 2026 stood at 19.84% (up 3514.0% YoY), while the FY2025 annual figure was 20.63%, up 4607.0% from the prior year.
  • Net Margin eased to 39.76% in Q1 2026 per TWST's latest filing, from 29.42% in the prior quarter.
  • Across five years, Net Margin topped out at 21.22% in Q2 2025 and bottomed at 126.06% in Q1 2022.
  • Historically, Net Margin has averaged 63.38% across 5 years, with a median of 60.35% in 2024.
  • Annual changes were most pronounced in 2024 — Net Margin plunged 1500 bps — and 2025, when it surged 12626 bps.
  • Twist Bioscience's Net Margin stood at 77.1% in 2022, then increased by 22 bps to 60.12% in 2023, then surged by 41 bps to 35.62% in 2024, then advanced by 17 bps to 29.42% in 2025, then plunged by 35 bps to 39.76% in 2026.
  • Business Quant data shows TWST's Net Margin at 39.76% in Q1 2026, 29.42% in Q4 2025, and 27.37% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Margin (Qtr)
1 Thermo Fisher Scientific 213.88 Bn 209.81 Bn 8.34 Bn 14.65%
2 Danaher 140.65 Bn 136.30 Bn 3.61 Bn 13.89%
3 Idexx Laboratories 46.02 Bn 45.83 Bn 779.09 Mn 27.82%
4 Agilent Technologies 39.85 Bn 38.05 Bn 990.00 Mn 18.47%
5 Iqvia Holdings 39.20 Bn 37.12 Bn 1.44 Bn 5.52%
6 Natera 38.80 Bn 37.70 Bn 696.04 Mn -12.22%
7 Illumina 30.11 Bn 28.94 Bn 770.00 Mn 17.86%
8 Mettler Toledo International 28.66 Bn 28.61 Bn 650.22 Mn 22.67%
9 Quest Diagnostics 26.24 Bn 25.61 Bn 1.03 Bn 10.65%
10 Twist Bioscience 7.18 Bn 7.02 Bn 62.45 Mn -29.61%

Historic Data

Download Data
DateValue
Jun 30, 2026 -29.61%
Mar 31, 2026 -39.76%
Dec 31, 2025 -29.42%
Sep 30, 2025 -27.37%
Jun 30, 2025 21.22%
Mar 31, 2025 -42.38%
Dec 31, 2024 -35.62%
Sep 30, 2024 -40.91%
Jun 30, 2024 -105.04%
Mar 31, 2024 -60.35%
Dec 31, 2023 -60.12%
Sep 30, 2023 -69.15%
Jun 30, 2023 -90.05%
Mar 31, 2023 -98.34%
Dec 31, 2022 -77.10%
Sep 30, 2022 -89.22%
Jun 30, 2022 -107.85%
Mar 31, 2022 -126.06%
Dec 31, 2021 -108.44%
Sep 30, 2021 -108.67%