Twist Bioscience (TWST) Net Margin (2017 - 2026)
Twist Bioscience (TWST) posted quarterly Net Margin of 39.76% for Q1 2026, up 262.0% year-over-year from 10.98% in Q1 2025, and down 35.15% quarter-over-quarter from 29.42% in Q4 2025.
Twist Bioscience (TWST) Net Margin (2017 - 2026) Analysis & Trends
Twist Bioscience (TWST) has reported Net Margin for 10 consecutive years, with 39.76% the latest figure, recorded in Q1 2026.
- In Q1 2026, Net Margin rose 262.0% year-over-year to 39.76%; the TTM figure through Mar 2026 stood at 19.84% (up 3514.0% YoY), while the FY2025 annual figure was 20.63%, up 4607.0% from the prior year.
- Net Margin eased to 39.76% in Q1 2026 per TWST's latest filing, from 29.42% in the prior quarter.
- Across five years, Net Margin topped out at 21.22% in Q2 2025 and bottomed at 126.06% in Q1 2022.
- Historically, Net Margin has averaged 63.38% across 5 years, with a median of 60.35% in 2024.
- Annual changes were most pronounced in 2024 — Net Margin plunged 1500 bps — and 2025, when it surged 12626 bps.
- Twist Bioscience's Net Margin stood at 77.1% in 2022, then increased by 22 bps to 60.12% in 2023, then surged by 41 bps to 35.62% in 2024, then advanced by 17 bps to 29.42% in 2025, then plunged by 35 bps to 39.76% in 2026.
- Business Quant data shows TWST's Net Margin at 39.76% in Q1 2026, 29.42% in Q4 2025, and 27.37% in Q3 2025.
Powered by 
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Thermo Fisher Scientific | 234.15 Bn | 230.09 Bn | 8.34 Bn | 14.65% |
| 2 | Danaher | 152.10 Bn | 147.75 Bn | 3.61 Bn | 13.89% |
| 3 | Natera | 48.48 Bn | 47.38 Bn | 486.15 Mn | -8.89% |
| 4 | Agilent Technologies | 44.35 Bn | 42.55 Bn | 990.00 Mn | 18.47% |
| 5 | Iqvia Holdings | 43.68 Bn | 41.60 Bn | 1.44 Bn | 5.52% |
| 6 | Idexx Laboratories | 43.02 Bn | 42.83 Bn | 779.09 Mn | 27.82% |
| 7 | Illumina | 34.39 Bn | 33.22 Bn | 770.00 Mn | 17.86% |
| 8 | Mettler Toledo International | 28.29 Bn | 28.24 Bn | 650.22 Mn | 22.67% |
| 9 | Labcorp Holdings | 27.51 Bn | 27.37 Bn | 1.11 Bn | 8.02% |
| 10 | Twist Bioscience | 9.55 Bn | 9.38 Bn | 62.45 Mn | -29.61% |
Historic Data
Download Data| Date | Value |
|---|---|
| Jun 30, 2026 | -29.61% |
| Mar 31, 2026 | -39.76% |
| Dec 31, 2025 | -29.46% |
| Sep 30, 2025 | -27.37% |
| Jun 30, 2025 | 21.22% |
| Mar 31, 2025 | -42.41% |
| Dec 31, 2024 | -35.62% |
| Sep 30, 2024 | -40.91% |
| Jun 30, 2024 | -105.05% |
| Mar 31, 2024 | -60.41% |
| Dec 31, 2023 | -60.15% |
| Sep 30, 2023 | -69.11% |
| Jun 30, 2023 | -90.05% |
| Mar 31, 2023 | -98.34% |
| Dec 31, 2022 | -77.10% |
| Sep 30, 2022 | -89.20% |
| Jun 30, 2022 | -107.85% |
| Mar 31, 2022 | -126.06% |
| Dec 31, 2021 | -108.44% |
| Sep 30, 2021 | -108.67% |