Twist Bioscience (TWST) EBITDA (2017 - 2026)

Twist Bioscience (TWST) posted quarterly EBITDA of -$44.1 million for Q1 2026, down 12.12% YoY from -$50.2 million in Q1 2025, and down 44.79% sequentially from -$30.5 million in Q4 2025.

Twist Bioscience (TWST) EBITDA (2017 - 2026) Analysis & Trends

Twist Bioscience has disclosed EBITDA across 10 years of filings, most recently posting -$44.1 million for Q1 2026.

  • In Q1 2026, EBITDA fell 12.12% year-over-year to -$44.1 million; the TTM figure through Mar 2026 stood at -$81.3 million (up 57.49% YoY), while the FY2025 annual figure was -$77.8 million, up 62.7% from the prior year.
  • EBITDA declined to -$44.1 million in Q1 2026, from -$30.5 million in the prior quarter.
  • Over the last five years, EBITDA for TWST reached as high as $20.2 million in Q2 2025 and fell as low as -$85.6 million in Q2 2024.
  • The 5-year median for EBITDA is -$44.1 million (2026), against an average of -$43.6 million.
  • Annual changes were most pronounced in 2022 — EBITDA slumped 62.41% — and 2025, when it soared 123.57%.
  • A 5-year view of EBITDA shows it stood at -$43.1 million in 2022, then gained by 0.56% to -$42.8 million in 2023, then grew by 25.91% to -$31.7 million in 2024, then grew by 4.0% to -$30.5 million in 2025, then plunged by 44.79% to -$44.1 million in 2026.
  • According to Business Quant data, EBITDA over the past three periods registered -$44.1 million, -$30.5 million, and -$26.9 million for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Waters 31,055.11 Bn 31,054.65 Bn 1.11 Bn -47.00 Mn
2 Thermo Fisher Scientific 191.02 Bn 187.77 Bn 7.74 Bn 1.86 Bn
3 Danaher 137.16 Bn 131.47 Bn 3.59 Bn 1.34 Bn
4 Idexx Laboratories 42.82 Bn 42.62 Bn 722.74 Mn 362.59 Mn
5 Natera 39.09 Bn 37.99 Bn 696.04 Mn -85.04 Mn
6 Agilent Technologies 37.61 Bn 35.81 Bn 990.00 Mn 399.00 Mn
7 Iqvia Holdings 34.23 Bn 32.25 Bn 1.36 Bn 514.00 Mn
8 Illumina 28.14 Bn 26.98 Bn 721.00 Mn 209.00 Mn
9 Mettler Toledo International 26.40 Bn 26.33 Bn 555.82 Mn 183.97 Mn
10 Twist Bioscience 6.31 Bn 6.14 Bn 57.12 Mn -44.09 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -44.09 Mn
Dec 31, 2025 -30.45 Mn
Sep 30, 2025 -26.90 Mn
Jun 30, 2025 20.19 Mn
Mar 31, 2025 -39.32 Mn
Dec 31, 2024 -31.72 Mn
Sep 30, 2024 -34.44 Mn
Jun 30, 2024 -85.65 Mn
Mar 31, 2024 -45.59 Mn
Dec 31, 2023 -42.82 Mn
Sep 30, 2023 -46.36 Mn
Jun 30, 2023 -58.14 Mn
Mar 31, 2023 -58.44 Mn
Dec 31, 2022 -43.06 Mn
Sep 30, 2022 -51.58 Mn
Jun 30, 2022 -61.42 Mn
Mar 31, 2022 -61.51 Mn
Dec 31, 2021 -45.38 Mn
Sep 30, 2021 -41.12 Mn
Jun 30, 2021 -39.80 Mn