Twist Bioscience (TWST) EBITDA (2017 - 2026)

Twist Bioscience (TWST) reported EBITDA of -$44.1 million for Q1 2026, down 12.12% year-over-year from -$50.2 million in Q1 2025, and down 44.79% quarter-over-quarter from -$30.5 million in Q4 2025.

Twist Bioscience (TWST) EBITDA (2017 - 2026) Analysis & Trends

Twist Bioscience (TWST) has 10 years of EBITDA data on file, last reported at -$44.1 million in Q1 2026.

  • EBITDA for Q1 2026 came in at -$44.1 million, down 12.12% year-over-year; the trailing twelve-month figure through Mar 2026 was -$81.3 million (up 57.49% YoY), and the FY2025 annual result was -$77.8 million, up 62.7% from the prior year.
  • EBITDA slipped to -$44.1 million in Q1 2026 per TWST's latest filing, from -$30.5 million in the prior quarter.
  • Over five years, EBITDA peaked at $20.2 million in Q2 2025 and troughed at -$85.6 million in Q2 2024.
  • A 5-year average of -$43.6 million and a median of -$44.1 million in 2026 frame the typical range for EBITDA.
  • The sharpest annual moves came in 2022 and 2025: EBITDA plunged 62.41% in 2022, then soared 123.57% in 2025.
  • A 5-year view of EBITDA shows it stood at -$43.1 million in 2022, then gained by 0.56% to -$42.8 million in 2023, then grew by 25.91% to -$31.7 million in 2024, then grew by 4.0% to -$30.5 million in 2025, then slumped by 44.79% to -$44.1 million in 2026.
  • Business Quant data shows TWST's EBITDA at -$44.1 million in Q1 2026, -$30.5 million in Q4 2025, and -$26.9 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Waters 29,902.70 Bn 29,902.24 Bn 1.11 Bn -47.00 Mn
2 Thermo Fisher Scientific 175.99 Bn 172.74 Bn 7.74 Bn 1.86 Bn
3 Danaher 129.87 Bn 124.18 Bn 3.59 Bn 1.34 Bn
4 Idexx Laboratories 44.75 Bn 44.55 Bn 722.74 Mn 362.59 Mn
5 Agilent Technologies 37.52 Bn 35.72 Bn 990.00 Mn 399.00 Mn
6 Iqvia Holdings 30.91 Bn 28.94 Bn 1.36 Bn 514.00 Mn
7 Natera 30.21 Bn 29.11 Bn 696.04 Mn -85.04 Mn
8 Illumina 24.19 Bn 23.04 Bn 721.00 Mn 209.00 Mn
9 Mettler Toledo International 23.12 Bn 23.06 Bn 555.82 Mn 183.97 Mn
10 Twist Bioscience 4.30 Bn 4.30 Bn 57.12 Mn -44.09 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -44.09 Mn
Dec 31, 2025 -30.45 Mn
Sep 30, 2025 -26.90 Mn
Jun 30, 2025 20.19 Mn
Mar 31, 2025 -39.32 Mn
Dec 31, 2024 -31.72 Mn
Sep 30, 2024 -34.44 Mn
Jun 30, 2024 -85.65 Mn
Mar 31, 2024 -45.59 Mn
Dec 31, 2023 -42.82 Mn
Sep 30, 2023 -46.36 Mn
Jun 30, 2023 -58.14 Mn
Mar 31, 2023 -58.44 Mn
Dec 31, 2022 -43.06 Mn
Sep 30, 2022 -51.58 Mn
Jun 30, 2022 -61.42 Mn
Mar 31, 2022 -61.51 Mn
Dec 31, 2021 -45.38 Mn
Sep 30, 2021 -41.12 Mn
Jun 30, 2021 -39.80 Mn