Twist Bioscience (TWST) EBITDA (2017 - 2026)
Twist Bioscience (TWST) posted quarterly EBITDA of -$44.1 million for Q1 2026, down 12.12% YoY from -$50.2 million in Q1 2025, and down 44.79% sequentially from -$30.5 million in Q4 2025.
Twist Bioscience (TWST) EBITDA (2017 - 2026) Analysis & Trends
Twist Bioscience has disclosed EBITDA across 10 years of filings, most recently posting -$44.1 million for Q1 2026.
- In Q1 2026, EBITDA fell 12.12% year-over-year to -$44.1 million; the TTM figure through Mar 2026 stood at -$81.3 million (up 57.49% YoY), while the FY2025 annual figure was -$77.8 million, up 62.7% from the prior year.
- EBITDA declined to -$44.1 million in Q1 2026, from -$30.5 million in the prior quarter.
- Over the last five years, EBITDA for TWST reached as high as $20.2 million in Q2 2025 and fell as low as -$85.6 million in Q2 2024.
- The 5-year median for EBITDA is -$44.1 million (2026), against an average of -$43.6 million.
- Annual changes were most pronounced in 2022 — EBITDA slumped 62.41% — and 2025, when it soared 123.57%.
- A 5-year view of EBITDA shows it stood at -$43.1 million in 2022, then gained by 0.56% to -$42.8 million in 2023, then grew by 25.91% to -$31.7 million in 2024, then grew by 4.0% to -$30.5 million in 2025, then plunged by 44.79% to -$44.1 million in 2026.
- According to Business Quant data, EBITDA over the past three periods registered -$44.1 million, -$30.5 million, and -$26.9 million for Q1 2026, Q4 2025, and Q3 2025 respectively.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA (Qtr) |
|---|---|---|---|---|---|
| 1 | Waters | 31,055.11 Bn | 31,054.65 Bn | 1.11 Bn | -47.00 Mn |
| 2 | Thermo Fisher Scientific | 191.02 Bn | 187.77 Bn | 7.74 Bn | 1.86 Bn |
| 3 | Danaher | 137.16 Bn | 131.47 Bn | 3.59 Bn | 1.34 Bn |
| 4 | Idexx Laboratories | 42.82 Bn | 42.62 Bn | 722.74 Mn | 362.59 Mn |
| 5 | Natera | 39.09 Bn | 37.99 Bn | 696.04 Mn | -85.04 Mn |
| 6 | Agilent Technologies | 37.61 Bn | 35.81 Bn | 990.00 Mn | 399.00 Mn |
| 7 | Iqvia Holdings | 34.23 Bn | 32.25 Bn | 1.36 Bn | 514.00 Mn |
| 8 | Illumina | 28.14 Bn | 26.98 Bn | 721.00 Mn | 209.00 Mn |
| 9 | Mettler Toledo International | 26.40 Bn | 26.33 Bn | 555.82 Mn | 183.97 Mn |
| 10 | Twist Bioscience | 6.31 Bn | 6.14 Bn | 57.12 Mn | -44.09 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -44.09 Mn |
| Dec 31, 2025 | -30.45 Mn |
| Sep 30, 2025 | -26.90 Mn |
| Jun 30, 2025 | 20.19 Mn |
| Mar 31, 2025 | -39.32 Mn |
| Dec 31, 2024 | -31.72 Mn |
| Sep 30, 2024 | -34.44 Mn |
| Jun 30, 2024 | -85.65 Mn |
| Mar 31, 2024 | -45.59 Mn |
| Dec 31, 2023 | -42.82 Mn |
| Sep 30, 2023 | -46.36 Mn |
| Jun 30, 2023 | -58.14 Mn |
| Mar 31, 2023 | -58.44 Mn |
| Dec 31, 2022 | -43.06 Mn |
| Sep 30, 2022 | -51.58 Mn |
| Jun 30, 2022 | -61.42 Mn |
| Mar 31, 2022 | -61.51 Mn |
| Dec 31, 2021 | -45.38 Mn |
| Sep 30, 2021 | -41.12 Mn |
| Jun 30, 2021 | -39.80 Mn |