Twist Bioscience (TWST) EBITDA (2017 - 2026)
Twist Bioscience (TWST) posted quarterly EBITDA of -$45.9 million for Q1 2026, down 10.35% year-over-year from -$51.2 million in Q1 2025, and down 39.4% quarter-over-quarter from -$32.9 million in Q4 2025.
Twist Bioscience (TWST) EBITDA (2017 - 2026) Analysis & Trends
Twist Bioscience (TWST) has reported EBITDA for 10 consecutive years, with -$45.9 million the latest figure, recorded in Q1 2026.
- In Q1 2026, EBITDA fell 10.35% year-over-year to -$45.9 million; the TTM figure through Mar 2026 stood at -$138.8 million (up 30.99% YoY), while the FY2025 annual figure was -$136.3 million, up 38.3% from the prior year.
- EBITDA fell to -$45.9 million in Q1 2026 per TWST's latest filing, from -$32.9 million in the prior quarter.
- Across five years, EBITDA topped out at -$29.9 million in Q3 2025 and bottomed at -$88.9 million in Q2 2024.
- Historically, EBITDA has averaged -$48.9 million across 5 years, with a median of -$47.0 million in 2023.
- Annual changes were most pronounced in 2022 — EBITDA sank 59.99% — and 2025, when it jumped 66.13%.
- Twist Bioscience's EBITDA stood at -$44.6 million in 2022, then declined by 5.26% to -$47.0 million in 2023, then increased by 26.25% to -$34.6 million in 2024, then advanced by 5.03% to -$32.9 million in 2025, then plunged by 39.4% to -$45.9 million in 2026.
- Business Quant data shows TWST's EBITDA at -$45.9 million in Q1 2026, -$32.9 million in Q4 2025, and -$29.9 million in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA (Qtr) |
|---|---|---|---|---|---|
| 1 | Thermo Fisher Scientific | 213.77 Bn | 209.71 Bn | 8.34 Bn | 2.09 Bn |
| 2 | Danaher | 139.78 Bn | 135.43 Bn | 3.61 Bn | 1.13 Bn |
| 3 | Idexx Laboratories | 46.04 Bn | 45.85 Bn | 779.09 Mn | 425.57 Mn |
| 4 | Agilent Technologies | 39.68 Bn | 37.88 Bn | 990.00 Mn | 399.00 Mn |
| 5 | Iqvia Holdings | 39.34 Bn | 37.26 Bn | 1.44 Bn | 506.00 Mn |
| 6 | Natera | 38.75 Bn | 37.65 Bn | 696.04 Mn | -93.52 Mn |
| 7 | Illumina | 29.90 Bn | 28.73 Bn | 770.00 Mn | 245.00 Mn |
| 8 | Mettler Toledo International | 28.58 Bn | 28.53 Bn | 650.22 Mn | 328.45 Mn |
| 9 | Quest Diagnostics | 26.18 Bn | 25.55 Bn | 1.03 Bn | 459.00 Mn |
| 10 | Twist Bioscience | 6.99 Bn | 6.82 Bn | 62.45 Mn | -36.28 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Jun 30, 2026 | -36.28 Mn |
| Mar 31, 2026 | -45.86 Mn |
| Dec 31, 2025 | -32.90 Mn |
| Sep 30, 2025 | -29.93 Mn |
| Jun 30, 2025 | -30.12 Mn |
| Mar 31, 2025 | -41.56 Mn |
| Dec 31, 2024 | -34.64 Mn |
| Sep 30, 2024 | -36.04 Mn |
| Jun 30, 2024 | -88.92 Mn |
| Mar 31, 2024 | -48.89 Mn |
| Dec 31, 2023 | -46.98 Mn |
| Sep 30, 2023 | -50.11 Mn |
| Jun 30, 2023 | -60.78 Mn |
| Mar 31, 2023 | -61.64 Mn |
| Dec 31, 2022 | -44.63 Mn |
| Sep 30, 2022 | -56.87 Mn |
| Jun 30, 2022 | -61.16 Mn |
| Mar 31, 2022 | -60.80 Mn |
| Dec 31, 2021 | -55.94 Mn |
| Sep 30, 2021 | -39.81 Mn |