Twist Bioscience (TWST) Net Margin (2017 - 2026)
Twist Bioscience's Net Margin came in at -29.65% for fiscal Q3 2026 (quarter ended Jun 30, 2026), down 50.89 percentage points from 21.24% a year earlier but up 10.11 percentage points from the prior quarter.
Twist Bioscience (TWST) Net Margin (2017 - 2026) Analysis & Trends
Over the trailing twelve months to Jun 30, 2026, Twist Bioscience reported Net Margin of -31.68%, down 8.18 percentage points year-over-year; for FY2025 (ended Sep 30, 2025), it came in at -20.63%, up 46.06 percentage points from FY2024.
- Net Margin has increased in each of the last eight fiscal years, with a five-year change of +134.67 percentage points (FY2020 to FY2025).
- Going back by fiscal year, Net Margin was -66.69% in FY2024 (+16.79 pp), -83.48% in FY2023 (+23.56 pp), -107.04% in FY2022 (+7.89 pp) and -114.94% in FY2021 (+40.37 pp).
- The five-year range for quarterly Net Margin is -126.06% (fiscal Q2 2022) to 21.24% (fiscal Q3 2025).
- Year-over-year, Net Margin increased in seven of the last eight quarters, with an average year-over-year change of +21.06 percentage points.
- The fastest year-over-year change in Net Margin over five years came in fiscal Q3 2025 (a gain of 126.31 percentage points), and the weakest in fiscal Q3 2026 (a drop of 50.89 percentage points).
- Business Quant data shows TWST's Net Margin at -39.76% (Q2 2026), -29.42% (Q1 2026) and -27.44% (Q4 2025) in the three fiscal quarters before Q3 2026.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Thermo Fisher Scientific | 243.20 Bn | 222.35 Bn | 4.88 Bn | 14.47% |
| 2 | Abbott Laboratories | 172.35 Bn | 143.43 Bn | 7.27 Bn | 7.37% |
| 3 | Danaher | 154.53 Bn | 138.35 Bn | 3.61 Bn | 13.89% |
| 4 | Intuitive Surgical | 150.04 Bn | 129.59 Bn | 1.96 Bn | 28.29% |
| 5 | Medtronic | 113.25 Bn | 79.11 Bn | 6.34 Bn | 15.07% |
| 6 | Stryker | 106.37 Bn | 92.49 Bn | 4.50 Bn | 19.37% |
| 7 | Boston Scientific | 61.94 Bn | 56.95 Bn | 3.85 Bn | 16.67% |
| 8 | Becton Dickinson | 50.05 Bn | 47.20 Bn | 2.32 Bn | 7.57% |
| 9 | Edwards Lifesciences | 49.13 Bn | 33.24 Bn | 1.35 Bn | 13.89% |
| 10 | Twist Bioscience | 10.01 Bn | 9.25 Bn | 62.45 Mn | -29.65% |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -29.65% |
| Mar 31, 2026 | -39.76% |
| Dec 31, 2025 | -29.42% |
| Sep 30, 2025 | -27.44% |
| Jun 30, 2025 | 21.24% |
| Mar 31, 2025 | -42.38% |
| Dec 31, 2024 | -35.62% |
| Sep 30, 2024 | -40.88% |
| Jun 30, 2024 | -105.08% |
| Mar 31, 2024 | -60.42% |
| Dec 31, 2023 | -60.15% |
| Sep 30, 2023 | -69.08% |
| Jun 30, 2023 | -90.05% |
| Mar 31, 2023 | -98.30% |
| Dec 31, 2022 | -77.10% |
| Sep 30, 2022 | -89.26% |
| Jun 30, 2022 | -107.85% |
| Mar 31, 2022 | -126.06% |
| Dec 31, 2021 | -108.44% |
| Sep 30, 2021 | -108.67% |
Twist Bioscience Net Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=net-margin&ticker=TWST&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "net-margin", "ticker": "TWST", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=net-margin&ticker=TWST&period=max&api_key=YOUR_API_KEY");
const data = await res.json();