Twist Bioscience Corp (TWST) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

57,432,584Shares Outstanding

2,229,690Shares held by institutions

$117,906,007Value of institutional holdings

101.71%Institutional ownership %

4.24%Shares Changed QoQ

224No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

According to SEC filings for the period ending December 2025, Twist Bioscience Corp (NASDAQ:TWST) is held by 231 institutional firms.

Twist Bioscience saw its institutional ownership percentage fell to 119.9% in December 2025 from 122.4% in September 2025.
Institutional share ownership changed by 4.27% QoQ, while the number of institutional owners saw a decrease of 4.55% YoY.
The latest 13F cycle for Twist Bioscience reveals that of 231 total investors, 116 funds grew their exposure, whereas 74 reduced theirs and 41 made no changes.
The aggregate institutional position in Twist Bioscience now stands at 73.18Mn shares as of December 2025, after investors increased their holdings (up by 3.00Mn shares quarter on quarter which is up 6.81Mn shares year over year).
ARK Investment Management LLC continues to be the largest institutional holder of Twist Bioscience as of December 31, 2025, with a position of 7.56Mn shares, representing 12.39% of the company's outstanding stock.
Among the most significant buyers of Twist Bioscience during December 2025 were WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC (1.81Mn), EdgePoint Investment Group Inc. (1.30Mn), ARK Investment Management LLC (832.69K), STATE STREET CORP (538.75K), STEMPOINT CAPITAL LP (518.36K).
Leading sellers of Twist Bioscience stock in December 2025 included JPMORGAN CHASE & CO (803.09K), MORGAN STANLEY (625.75K), Artisan Partners Limited Partnership (580.70K), Qube Research & Technologies Ltd (400.46K), JACOBS LEVY EQUITY MANAGEMENT, INC (394.02K).
The top 10 institutional holders of Twist Bioscience for the quarter ending December 2025 included ARK Investment Management LLC (7.56Mn), WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC (5.95Mn), BlackRock, Inc. (5.89Mn), Artisan Partners Limited Partnership (5.83Mn), VANGUARD GROUP INC (5.78Mn), EdgePoint Investment Group Inc. (5.38Mn), STATE STREET CORP (3.63Mn), Amova Asset Management Americas, Inc. (1.90Mn), Sumitomo Mitsui Trust Group, Inc. (1.90Mn), Soleus Capital Management, L.P. (1.86Mn).

231 Institutional Holders

2,229,690 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
ARK Investment Management LLC	31 Dec, 2025	7,559,495	832,687	12.38%	$239,787,194.00
WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC	31 Dec, 2025	5,954,429	1,812,146	43.75%	$188,874,488.00
BlackRock, Inc.	31 Dec, 2025	5,894,972	-283,404	-4.59%	$186,988,511.00
Artisan Partners Limited Partnership	31 Dec, 2025	5,830,205	-580,695	-9.06%	$184,934,095.00
VANGUARD GROUP INC	31 Dec, 2025	5,776,198	8,049	0.14%	$183,221,001.00
EdgePoint Investment Group Inc.	31 Dec, 2025	5,377,991	1,295,672	31.74%	$170,589,875.00
STATE STREET CORP	31 Dec, 2025	3,627,818	538,755	17.44%	$115,074,387.00
Amova Asset Management Americas, Inc.	31 Dec, 2025	1,902,829	-217,377	-10.25%	$60,262,594.00
Sumitomo Mitsui Trust Group, Inc.	31 Dec, 2025	1,902,829	-217,377	-10.25%	$60,357,736.00
Soleus Capital Management, L.P.	31 Dec, 2025	1,861,802	-4,432	-0.24%	$59,056,359.00
GOLDMAN SACHS GROUP INC	31 Dec, 2025	1,696,594	69,574	4.28%	$53,815,962.00
MILLENNIUM MANAGEMENT LLC	31 Dec, 2025	1,497,746	-296,104	-16.51%	$47,508,503.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	1,459,274	10,861	0.75%	$46,296,523.00
THRIVENT FINANCIAL FOR LUTHERANS	31 Dec, 2025	1,361,355	-101,730	-6.95%	$43,182.00
BAILLIE GIFFORD & CO	31 Dec, 2025	1,276,195	13,456	1.07%	$40,480,906.00
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	31 Dec, 2025	1,173,100	49,403	4.40%	$37,210,731.00
First Light Asset Management, LLC	31 Dec, 2025	1,140,771	-54,112	-4.53%	$36,185,256.00
MORGAN STANLEY	31 Dec, 2025	866,356	-625,750	-41.94%	$27,480,827.00
AMERICAN CENTURY COMPANIES INC	31 Dec, 2025	865,634	27,570	3.29%	$27,457,993.00
Tao Capital Management LP	31 Dec, 2025	828,815	0	0.00%	$26,290,012.00

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