Twist Bioscience (TWST) Operating Income (2017 - 2026)

Twist Bioscience (TWST) posted quarterly Operating Income of -$45.9 million for Q1 2026, down 10.35% YoY from -$51.2 million in Q1 2025, and down 39.4% sequentially from -$32.9 million in Q4 2025.

Twist Bioscience (TWST) Operating Income (2017 - 2026) Analysis & Trends

Twist Bioscience has disclosed Operating Income across 10 years of filings, most recently posting -$45.9 million for Q1 2026.

  • In Q1 2026, Operating Income fell 10.35% year-over-year to -$45.9 million; the TTM figure through Mar 2026 stood at -$138.8 million (up 30.99% YoY), while the FY2025 annual figure was -$136.3 million, up 38.3% from the prior year.
  • Operating Income declined to -$45.9 million in Q1 2026, from -$32.9 million in the prior quarter.
  • Over the last five years, Operating Income for TWST reached as high as -$29.9 million in Q3 2025 and fell as low as -$88.9 million in Q2 2024.
  • The 5-year median for Operating Income is -$47.0 million (2023), against an average of -$48.9 million.
  • Annual changes were most pronounced in 2022 — Operating Income tumbled 59.99% — and 2025, when it jumped 66.13%.
  • A 5-year view of Operating Income shows it stood at -$44.6 million in 2022, then dropped by 5.26% to -$47.0 million in 2023, then grew by 26.25% to -$34.6 million in 2024, then gained by 5.03% to -$32.9 million in 2025, then sank by 39.4% to -$45.9 million in 2026.
  • According to Business Quant data, Operating Income over the past three periods registered -$45.9 million, -$32.9 million, and -$29.9 million for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Waters 31,055.11 Bn 31,054.65 Bn 1.11 Bn -47.00 Mn
2 Thermo Fisher Scientific 191.02 Bn 187.77 Bn 7.74 Bn 1.86 Bn
3 Danaher 137.16 Bn 131.47 Bn 3.59 Bn 1.34 Bn
4 Idexx Laboratories 42.82 Bn 42.62 Bn 722.74 Mn 362.59 Mn
5 Natera 39.09 Bn 37.99 Bn 696.04 Mn -93.52 Mn
6 Agilent Technologies 37.61 Bn 35.81 Bn 990.00 Mn 399.00 Mn
7 Iqvia Holdings 34.23 Bn 32.25 Bn 1.36 Bn 514.00 Mn
8 Illumina 28.14 Bn 26.98 Bn 721.00 Mn 209.00 Mn
9 Mettler Toledo International 26.40 Bn 26.33 Bn 555.82 Mn 238.95 Mn
10 Twist Bioscience 6.31 Bn 6.14 Bn 57.12 Mn -45.86 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -45.86 Mn
Dec 31, 2025 -32.90 Mn
Sep 30, 2025 -29.93 Mn
Jun 30, 2025 -30.12 Mn
Mar 31, 2025 -41.56 Mn
Dec 31, 2024 -34.64 Mn
Sep 30, 2024 -36.04 Mn
Jun 30, 2024 -88.92 Mn
Mar 31, 2024 -48.89 Mn
Dec 31, 2023 -46.98 Mn
Sep 30, 2023 -50.11 Mn
Jun 30, 2023 -60.78 Mn
Mar 31, 2023 -61.64 Mn
Dec 31, 2022 -44.63 Mn
Sep 30, 2022 -56.87 Mn
Jun 30, 2022 -61.16 Mn
Mar 31, 2022 -60.80 Mn
Dec 31, 2021 -55.94 Mn
Sep 30, 2021 -39.81 Mn
Jun 30, 2021 -42.12 Mn