Twist Bioscience (TWST) Operating Income (2017 - 2026)
Twist Bioscience (TWST) reported Operating Income of -$45.9 million for Q1 2026, down 10.35% year-over-year from -$51.2 million in Q1 2025, and down 39.4% quarter-over-quarter from -$32.9 million in Q4 2025.
Twist Bioscience (TWST) Operating Income (2017 - 2026) Analysis & Trends
Twist Bioscience (TWST) has 10 years of Operating Income data on file, last reported at -$45.9 million in Q1 2026.
- Operating Income for Q1 2026 came in at -$45.9 million, down 10.35% year-over-year; the trailing twelve-month figure through Mar 2026 was -$138.8 million (up 30.99% YoY), and the FY2025 annual result was -$136.3 million, up 38.3% from the prior year.
- Operating Income slipped to -$45.9 million in Q1 2026 per TWST's latest filing, from -$32.9 million in the prior quarter.
- Over five years, Operating Income peaked at -$29.9 million in Q3 2025 and troughed at -$88.9 million in Q2 2024.
- A 5-year average of -$48.9 million and a median of -$47.0 million in 2023 frame the typical range for Operating Income.
- The sharpest annual moves came in 2022 and 2025: Operating Income sank 59.99% in 2022, then jumped 66.13% in 2025.
- A 5-year view of Operating Income shows it stood at -$44.6 million in 2022, then dropped by 5.26% to -$47.0 million in 2023, then grew by 26.25% to -$34.6 million in 2024, then gained by 5.03% to -$32.9 million in 2025, then tumbled by 39.4% to -$45.9 million in 2026.
- Business Quant data shows TWST's Operating Income at -$45.9 million in Q1 2026, -$32.9 million in Q4 2025, and -$29.9 million in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Op. Inc (Qtr) |
|---|---|---|---|---|---|
| 1 | Waters | 29,902.70 Bn | 29,902.24 Bn | 1.11 Bn | -47.00 Mn |
| 2 | Thermo Fisher Scientific | 175.99 Bn | 172.74 Bn | 7.74 Bn | 1.86 Bn |
| 3 | Danaher | 129.87 Bn | 124.18 Bn | 3.59 Bn | 1.34 Bn |
| 4 | Idexx Laboratories | 44.75 Bn | 44.55 Bn | 722.74 Mn | 362.59 Mn |
| 5 | Agilent Technologies | 37.52 Bn | 35.72 Bn | 990.00 Mn | 399.00 Mn |
| 6 | Iqvia Holdings | 30.91 Bn | 28.94 Bn | 1.36 Bn | 514.00 Mn |
| 7 | Natera | 30.21 Bn | 29.11 Bn | 696.04 Mn | -93.52 Mn |
| 8 | Illumina | 24.19 Bn | 23.04 Bn | 721.00 Mn | 209.00 Mn |
| 9 | Mettler Toledo International | 23.12 Bn | 23.06 Bn | 555.82 Mn | 238.95 Mn |
| 10 | Twist Bioscience | 4.30 Bn | 4.30 Bn | 57.12 Mn | -45.86 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -45.86 Mn |
| Dec 31, 2025 | -32.90 Mn |
| Sep 30, 2025 | -29.93 Mn |
| Jun 30, 2025 | -30.12 Mn |
| Mar 31, 2025 | -41.56 Mn |
| Dec 31, 2024 | -34.64 Mn |
| Sep 30, 2024 | -36.04 Mn |
| Jun 30, 2024 | -88.92 Mn |
| Mar 31, 2024 | -48.89 Mn |
| Dec 31, 2023 | -46.98 Mn |
| Sep 30, 2023 | -50.11 Mn |
| Jun 30, 2023 | -60.78 Mn |
| Mar 31, 2023 | -61.64 Mn |
| Dec 31, 2022 | -44.63 Mn |
| Sep 30, 2022 | -56.87 Mn |
| Jun 30, 2022 | -61.16 Mn |
| Mar 31, 2022 | -60.80 Mn |
| Dec 31, 2021 | -55.94 Mn |
| Sep 30, 2021 | -39.81 Mn |
| Jun 30, 2021 | -42.12 Mn |