Twist Bioscience (TWST) EBITDA Margin (2017 - 2026)
Twist Bioscience's EBITDA Margin came in at -24.92% for fiscal Q3 2026 (quarter ended Jun 30, 2026), up 0.12 percentage points from -25.04% a year earlier and up 10.71 percentage points from the prior quarter.
Twist Bioscience (TWST) EBITDA Margin (2017 - 2026) Analysis & Trends
Over the trailing twelve months to Jun 30, 2026, Twist Bioscience reported EBITDA Margin of -27.70%, up 4.56 percentage points year-over-year; for FY2025 (ended Sep 30, 2025), it was -29.58%, up 30.93 percentage points from FY2024.
- EBITDA Margin has increased in each of the last eight fiscal years, with a five-year change of +118.45 percentage points (FY2020 to FY2025).
- Going back by fiscal year, EBITDA Margin was -60.52% in FY2024 (+16.12 pp), -76.64% in FY2023 (+30.58 pp), -107.22% in FY2022 (+0.78 pp) and -108.00% in FY2021 (+40.03 pp).
- The five-year range for quarterly EBITDA Margin is -125.64% (fiscal Q1 2022) to -24.17% (fiscal Q4 2025).
- Year-over-year, EBITDA Margin has increased for eight consecutive quarters, with an average year-over-year change of +19.85 percentage points over the last eight quarters.
- The fastest year-over-year change in EBITDA Margin over five years came in fiscal Q3 2025 (a gain of 73.92 percentage points), and the weakest in fiscal Q4 2021 (a drop of 30.36 percentage points).
- Business Quant data shows TWST's EBITDA Margin at -35.63% (Q2 2026), -25.75% (Q1 2026) and -24.17% (Q4 2025) in the three fiscal quarters before Q3 2026.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Thermo Fisher Scientific | 243.20 Bn | 222.35 Bn | 4.88 Bn | 24.20% |
| 2 | Abbott Laboratories | 172.35 Bn | 143.43 Bn | 7.27 Bn | 21.86% |
| 3 | Danaher | 154.53 Bn | 138.35 Bn | 3.61 Bn | 28.51% |
| 4 | Intuitive Surgical | 150.04 Bn | 129.59 Bn | 1.96 Bn | 41.08% |
| 5 | Medtronic | 113.25 Bn | 79.11 Bn | 6.34 Bn | 25.55% |
| 6 | Stryker | 106.37 Bn | 92.49 Bn | 4.50 Bn | 29.67% |
| 7 | Boston Scientific | 61.94 Bn | 56.95 Bn | 3.85 Bn | 28.17% |
| 8 | Becton Dickinson | 50.05 Bn | 47.20 Bn | 2.32 Bn | 24.62% |
| 9 | Edwards Lifesciences | 49.13 Bn | 33.24 Bn | 1.35 Bn | 31.93% |
| 10 | Twist Bioscience | 10.01 Bn | 9.25 Bn | 62.45 Mn | -24.92% |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -24.92% |
| Mar 31, 2026 | -35.63% |
| Dec 31, 2025 | -25.75% |
| Sep 30, 2025 | -24.17% |
| Jun 30, 2025 | -25.04% |
| Mar 31, 2025 | -37.89% |
| Dec 31, 2024 | -31.86% |
| Sep 30, 2024 | -34.69% |
| Jun 30, 2024 | -98.97% |
| Mar 31, 2024 | -53.90% |
| Dec 31, 2023 | -54.28% |
| Sep 30, 2023 | -62.16% |
| Jun 30, 2023 | -82.04% |
| Mar 31, 2023 | -90.74% |
| Dec 31, 2022 | -72.52% |
| Sep 30, 2022 | -90.60% |
| Jun 30, 2022 | -101.08% |
| Mar 31, 2022 | -118.09% |
| Dec 31, 2021 | -125.63% |
| Sep 30, 2021 | -98.33% |
Twist Bioscience EBITDA Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=ebitda-margin&ticker=TWST&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "ebitda-margin", "ticker": "TWST", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=ebitda-margin&ticker=TWST&period=max&api_key=YOUR_API_KEY");
const data = await res.json();