Twist Bioscience (TWST) EBITDA Margin (2017 - 2026)
Twist Bioscience (TWST) posted quarterly EBITDA Margin of 41.42% for Q1 2026, up 336.0% year-over-year from 9.5% in Q1 2025, and down 30.57% quarter-over-quarter from 31.73% in Q4 2025.
Twist Bioscience (TWST) EBITDA Margin (2017 - 2026) Analysis & Trends
Twist Bioscience (TWST) has reported EBITDA Margin for 10 consecutive years, with 41.42% the latest figure, recorded in Q1 2026.
- In Q1 2026, EBITDA Margin rose 336.0% year-over-year to 41.42%; the TTM figure through Mar 2026 stood at 33.9% (up 2396.0% YoY), while the FY2025 annual figure was 36.18%, up 3437.0% from the prior year.
- EBITDA Margin eased to 41.42% in Q1 2026 per TWST's latest filing, from 31.73% in the prior quarter.
- Across five years, EBITDA Margin topped out at 30.23% in Q3 2025 and bottomed at 126.34% in Q1 2022.
- Historically, EBITDA Margin has averaged 70.02% across 5 years, with a median of 65.7% in 2023.
- Annual changes were most pronounced in 2024 — EBITDA Margin slumped 1380 bps — and 2025, when it soared 7780 bps.
- Twist Bioscience's EBITDA Margin stood at 82.28% in 2022, then grew by 20 bps to 65.7% in 2023, then soared by 41 bps to 39.05% in 2024, then gained by 19 bps to 31.73% in 2025, then tumbled by 31 bps to 41.42% in 2026.
- Business Quant data shows TWST's EBITDA Margin at 41.42% in Q1 2026, 31.73% in Q4 2025, and 30.23% in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Thermo Fisher Scientific | 213.88 Bn | 209.81 Bn | 8.34 Bn | 17.40% |
| 2 | Danaher | 140.65 Bn | 136.30 Bn | 3.61 Bn | 17.99% |
| 3 | Idexx Laboratories | 46.02 Bn | 45.83 Bn | 779.09 Mn | 34.98% |
| 4 | Agilent Technologies | 39.85 Bn | 38.05 Bn | 990.00 Mn | 21.74% |
| 5 | Iqvia Holdings | 39.20 Bn | 37.12 Bn | 1.44 Bn | 11.58% |
| 6 | Natera | 38.80 Bn | 37.70 Bn | 696.04 Mn | -13.42% |
| 7 | Illumina | 30.11 Bn | 28.94 Bn | 770.00 Mn | 21.14% |
| 8 | Mettler Toledo International | 28.66 Bn | 28.61 Bn | 650.22 Mn | 31.97% |
| 9 | Quest Diagnostics | 26.24 Bn | 25.61 Bn | 1.03 Bn | 15.08% |
| 10 | Twist Bioscience | 7.18 Bn | 7.02 Bn | 62.45 Mn | -30.65% |
Historic Data
Download Data| Date | Value |
|---|---|
| Jun 30, 2026 | -30.65% |
| Mar 31, 2026 | -41.42% |
| Dec 31, 2025 | -31.73% |
| Sep 30, 2025 | -30.23% |
| Jun 30, 2025 | -31.36% |
| Mar 31, 2025 | -44.79% |
| Dec 31, 2024 | -39.05% |
| Sep 30, 2024 | -42.55% |
| Jun 30, 2024 | -109.15% |
| Mar 31, 2024 | -64.92% |
| Dec 31, 2023 | -65.70% |
| Sep 30, 2023 | -74.85% |
| Jun 30, 2023 | -95.36% |
| Mar 31, 2023 | -102.42% |
| Dec 31, 2022 | -82.28% |
| Sep 30, 2022 | -99.24% |
| Jun 30, 2022 | -109.00% |
| Mar 31, 2022 | -126.34% |
| Dec 31, 2021 | -133.13% |
| Sep 30, 2021 | -104.90% |