Twist Bioscience (TWST) EBITDA Margin (2017 - 2026)
Twist Bioscience (TWST) reported EBITDA Margin of 39.82% for Q1 2026, up 256.0% year-over-year from 11.19% in Q1 2025, and down 35.61% quarter-over-quarter from 29.37% in Q4 2025.
Twist Bioscience (TWST) EBITDA Margin (2017 - 2026) Analysis & Trends
Twist Bioscience (TWST) has 10 years of EBITDA Margin data on file, last reported at 39.82% in Q1 2026.
- EBITDA Margin for Q1 2026 came in at 39.82%, up 256.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 19.84% (up 3513.0% YoY), and the FY2025 annual result was 20.65%, up 4596.0% from the prior year.
- EBITDA Margin eased to 39.82% in Q1 2026 per TWST's latest filing, from 29.37% in the prior quarter.
- Over five years, EBITDA Margin peaked at 21.02% in Q2 2025 and troughed at 127.8% in Q1 2022.
- A 5-year average of 63.76% and a median of 60.54% in 2024 frame the typical range for EBITDA Margin.
- The sharpest annual moves came in 2024 and 2025: EBITDA Margin plunged 1392 bps in 2024, then jumped 12615 bps in 2025.
- A 5-year view of EBITDA Margin shows it stood at 79.38% in 2022, then gained by 25 bps to 59.89% in 2023, then jumped by 40 bps to 35.76% in 2024, then rose by 18 bps to 29.37% in 2025, then tumbled by 36 bps to 39.82% in 2026.
- Business Quant data shows TWST's EBITDA Margin at 39.82% in Q1 2026, 29.37% in Q4 2025, and 27.17% in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Waters | 29,902.70 Bn | 29,902.24 Bn | 1.11 Bn | -3.71% |
| 2 | Thermo Fisher Scientific | 175.99 Bn | 172.74 Bn | 7.74 Bn | 16.93% |
| 3 | Danaher | 129.87 Bn | 124.18 Bn | 3.59 Bn | 22.58% |
| 4 | Idexx Laboratories | 44.75 Bn | 44.55 Bn | 722.74 Mn | 31.78% |
| 5 | Agilent Technologies | 37.52 Bn | 35.72 Bn | 990.00 Mn | 21.74% |
| 6 | Iqvia Holdings | 30.91 Bn | 28.94 Bn | 1.36 Bn | 12.38% |
| 7 | Natera | 30.21 Bn | 29.11 Bn | 696.04 Mn | -12.21% |
| 8 | Illumina | 24.19 Bn | 23.04 Bn | 721.00 Mn | 19.16% |
| 9 | Mettler Toledo International | 23.12 Bn | 23.06 Bn | 555.82 Mn | 19.42% |
| 10 | Twist Bioscience | 4.30 Bn | 4.30 Bn | 57.12 Mn | -39.82% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -39.82% |
| Dec 31, 2025 | -29.37% |
| Sep 30, 2025 | -27.17% |
| Jun 30, 2025 | 21.02% |
| Mar 31, 2025 | -42.38% |
| Dec 31, 2024 | -35.76% |
| Sep 30, 2024 | -40.66% |
| Jun 30, 2024 | -105.13% |
| Mar 31, 2024 | -60.54% |
| Dec 31, 2023 | -59.89% |
| Sep 30, 2023 | -69.26% |
| Jun 30, 2023 | -91.22% |
| Mar 31, 2023 | -97.10% |
| Dec 31, 2022 | -79.38% |
| Sep 30, 2022 | -90.01% |
| Jun 30, 2022 | -109.46% |
| Mar 31, 2022 | -127.80% |
| Dec 31, 2021 | -108.00% |
| Sep 30, 2021 | -108.36% |
| Jun 30, 2021 | -113.65% |