Twist Bioscience (TWST) EBITDA Margin (2017 - 2026)
Twist Bioscience (TWST) posted quarterly EBITDA Margin of 39.82% for Q1 2026, up 256.0% YoY from 11.19% in Q1 2025, and down 35.61% sequentially from 29.37% in Q4 2025.
Twist Bioscience (TWST) EBITDA Margin (2017 - 2026) Analysis & Trends
Twist Bioscience has disclosed EBITDA Margin across 10 years of filings, most recently posting 39.82% for Q1 2026.
- In Q1 2026, EBITDA Margin rose 256.0% year-over-year to 39.82%; the TTM figure through Mar 2026 stood at 19.84% (up 3513.0% YoY), while the FY2025 annual figure was 20.65%, up 4596.0% from the prior year.
- EBITDA Margin fell to 39.82% in Q1 2026, from 29.37% in the prior quarter.
- Over the last five years, EBITDA Margin for TWST reached as high as 21.02% in Q2 2025 and fell as low as 127.8% in Q1 2022.
- The 5-year median for EBITDA Margin is 60.54% (2024), against an average of 63.76%.
- Annual changes were most pronounced in 2024 — EBITDA Margin slumped 1392 bps — and 2025, when it jumped 12615 bps.
- A 5-year view of EBITDA Margin shows it stood at 79.38% in 2022, then gained by 25 bps to 59.89% in 2023, then jumped by 40 bps to 35.76% in 2024, then rose by 18 bps to 29.37% in 2025, then sank by 36 bps to 39.82% in 2026.
- According to Business Quant data, EBITDA Margin over the past three periods registered 39.82%, 29.37%, and 27.17% for Q1 2026, Q4 2025, and Q3 2025 respectively.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Waters | 31,055.11 Bn | 31,054.65 Bn | 1.11 Bn | -3.71% |
| 2 | Thermo Fisher Scientific | 191.02 Bn | 187.77 Bn | 7.74 Bn | 16.93% |
| 3 | Danaher | 137.16 Bn | 131.47 Bn | 3.59 Bn | 22.58% |
| 4 | Idexx Laboratories | 42.82 Bn | 42.62 Bn | 722.74 Mn | 31.78% |
| 5 | Natera | 39.09 Bn | 37.99 Bn | 696.04 Mn | -12.21% |
| 6 | Agilent Technologies | 37.61 Bn | 35.81 Bn | 990.00 Mn | 21.74% |
| 7 | Iqvia Holdings | 34.23 Bn | 32.25 Bn | 1.36 Bn | 12.38% |
| 8 | Illumina | 28.14 Bn | 26.98 Bn | 721.00 Mn | 19.16% |
| 9 | Mettler Toledo International | 26.40 Bn | 26.33 Bn | 555.82 Mn | 19.42% |
| 10 | Twist Bioscience | 6.31 Bn | 6.14 Bn | 57.12 Mn | -39.82% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -39.82% |
| Dec 31, 2025 | -29.37% |
| Sep 30, 2025 | -27.17% |
| Jun 30, 2025 | 21.02% |
| Mar 31, 2025 | -42.38% |
| Dec 31, 2024 | -35.76% |
| Sep 30, 2024 | -40.66% |
| Jun 30, 2024 | -105.13% |
| Mar 31, 2024 | -60.54% |
| Dec 31, 2023 | -59.89% |
| Sep 30, 2023 | -69.26% |
| Jun 30, 2023 | -91.22% |
| Mar 31, 2023 | -97.10% |
| Dec 31, 2022 | -79.38% |
| Sep 30, 2022 | -90.01% |
| Jun 30, 2022 | -109.46% |
| Mar 31, 2022 | -127.80% |
| Dec 31, 2021 | -108.00% |
| Sep 30, 2021 | -108.36% |
| Jun 30, 2021 | -113.65% |