Taysha Gene Therapies (TSHA) FCF Margin (2023 - 2025)

Taysha Gene Therapies (TSHA) posted FCF Margin of 2263.61% for Q4 2025, down 118.55% sequentially from 1035.75% in Q2 2025, and down 135827.0% YoY from N/an in Q4 2024.

Taysha Gene Therapies (TSHA) FCF Margin (2023 - 2025) Analysis & Trends

Taysha Gene Therapies has reported FCF Margin for 3 years, with the latest figure at 2263.61% in Q4 2025.

  • Quarterly FCF Margin fell 135827.0% year-over-year to 2263.61% in Q4 2025, while the trailing twelve-month figure through Mar 2026 was 3523.67% (down 236498.0% YoY) and the FY2025 annual result came in at 1705.96%, down 72674.0% from the prior year.
  • FCF Margin eased to 2263.61% in Q4 2025 per TSHA's latest filing, from 1035.75% in the prior quarter.
  • Over five years, FCF Margin peaked at 305.94% in Q3 2023 and troughed at 2263.61% in Q4 2025.
  • A 3-year average of 1005.02% and a median of 905.34% in 2024 frame the typical range for FCF Margin.
  • The widest YoY moves for FCF Margin: up 92549 bps in 2025, down 135827 bps in 2025.
  • Over 3 years, FCF Margin stood at 542.81% in 2023, then sank by 67 bps to 905.34% in 2024, then tumbled by 150 bps to 2263.61% in 2025.
  • According to Business Quant data, FCF Margin over the past three periods registered 2263.61%, 1035.75%, and 957.56% for Q4 2025, Q2 2025, and Q1 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) FCF Margin (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 30.39%
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 13.35%
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn -
4 Revolution Medicines 43.64 Bn 43.64 Bn - -
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 25.68%
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -77,594.17%
7 Royalty Pharma 33.72 Bn 35.84 Bn - 70.82%
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 22.62%
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -22.35%
10 Taysha Gene Therapies 1.94 Bn 1.94 Bn - -

Historic Data

Download Data
DateValue
Dec 31, 2025 -2,263.61%
Jun 30, 2025 -1,035.75%
Mar 31, 2025 -957.56%
Dec 31, 2024 -905.34%
Sep 30, 2024 -1,205.03%
Jun 30, 2024 -1,961.24%
Mar 31, 2024 -584.52%
Dec 31, 2023 -542.81%
Sep 30, 2023 -305.94%
Jun 30, 2023 -781.59%
Mar 31, 2023 -511.79%