Taysha Gene Therapies (TSHA) Net Margin (2023 - 2025)
Taysha Gene Therapies (TSHA) recorded Net Margin of -507.77% in Q4 2025, up 421.26 percentage points from -929.03% a year earlier.
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Analysis
Taysha Gene Therapies (TSHA) Net Margin (2023 - 2025) Analysis & Trends
For FY2025, Taysha Gene Therapies reported Net Margin of -1115.27%, down 43.65 percentage points from FY2024.
- Annual Net Margin has a three-year change of +5519.99 percentage points (FY2022 to FY2025).
- Across earlier years, Net Margin came in at -1071.62% in FY2024 (-349.56 pp), -722.06% in FY2023 (+5913.19 pp) and -6635.25% in FY2022.
- The Q4 2025 figure is the highest quarterly Net Margin since Q4 2023.
- On a year-over-year basis, Net Margin rose in three of the last seven quarters, with an average year-over-year change of -240.02 percentage points.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 645.01 Bn | 563.54 Bn | 17.26 Bn | 21.86% |
| 2 | AbbVie | 465.23 Bn | 438.39 Bn | 12.70 Bn | 21.27% |
| 3 | Merck | 368.40 Bn | 322.83 Bn | 12.21 Bn | -8.04% |
| 4 | Novartis Ag | 278.02 Bn | 233.89 Bn | 11.24 Bn | 22.61% |
| 5 | Astrazeneca | 254.57 Bn | 228.13 Bn | 12.86 Bn | 18.81% |
| 6 | Amgen | 229.02 Bn | 184.42 Bn | 7.24 Bn | 23.62% |
| 7 | Gilead Sciences | 187.74 Bn | 161.85 Bn | 6.22 Bn | -134.51% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | -1.65% |
| 9 | Vertex Pharmaceuticals | 133.45 Bn | 105.45 Bn | 2.84 Bn | 32.99% |
| 10 | Taysha Gene Therapies | 1.62 Bn | 1.62 Bn | - | - |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Dec 31, 2025 | -507.77% |
| Jun 30, 2025 | -1,353.58% |
| Mar 31, 2025 | -935.23% |
| Dec 31, 2024 | -929.03% |
| Sep 30, 2024 | -1,427.52% |
| Jun 30, 2024 | -1,882.01% |
| Mar 31, 2024 | -705.39% |
| Dec 31, 2023 | 1,324.67% |
| Sep 30, 2023 | -2,467.07% |
| Jun 30, 2023 | -1,027.06% |
| Mar 31, 2023 | -374.46% |
API Access
Taysha Gene Therapies Net Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=net-margin&ticker=TSHA&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "net-margin", "ticker": "TSHA", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=net-margin&ticker=TSHA&period=max&api_key=YOUR_API_KEY");
const data = await res.json();