Taysha Gene Therapies (TSHA) EBITDA (2020 - 2026)
Taysha Gene Therapies (TSHA) reported EBITDA of -$43.5 million for Q1 2026, down 103.01% on a YoY basis from $1.4 billion in Q1 2025, and down 53.66% sequentially from -$28.3 million in Q4 2025.
Taysha Gene Therapies (TSHA) EBITDA (2020 - 2026) Analysis & Trends
Taysha Gene Therapies (TSHA) has 7 years of EBITDA data on file, last reported at -$43.5 million in Q1 2026.
- For the quarter ending Q1 2026, EBITDA fell 103.01% year-over-year to -$43.5 million; the trailing twelve-month figure through Mar 2026 stood at -$132.6 million (down 49.7% YoY), and the FY2025 full-year result was -$110.5 million, down 20.82% from the prior year.
- EBITDA slipped to -$43.5 million in Q1 2026, from -$28.3 million in the prior quarter.
- In the past five years, EBITDA ranged from a high of -$16.2 million in Q4 2023 to a low of -$54.0 million in Q4 2022.
- A 5-year average of -$28.3 million and a median of -$25.5 million in 2022 frame the typical range for EBITDA.
- Across the five-year window, EBITDA soared 69.9% in 2023 and sank 103.01% in 2026, its largest moves.
- Tracing TSHA's EBITDA over 5 years: stood at -$54.0 million in 2022, then surged by 69.9% to -$16.2 million in 2023, then decreased by 22.69% to -$19.9 million in 2024, then plunged by 41.98% to -$28.3 million in 2025, then tumbled by 53.66% to -$43.5 million in 2026.
- Business Quant data shows TSHA's EBITDA at -$43.5 million in Q1 2026, -$28.3 million in Q4 2025, and -$34.0 million in Q3 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 67,072.09 Bn | 67,072.09 Bn | - | -27.75 Mn |
| 2 | Nanobiotix | 1,894.61 Bn | 1,894.55 Bn | - | - |
| 3 | Akari Therapeutics | 1,014.18 Bn | 1,014.18 Bn | - | -15.76 Mn |
| 4 | BeOne Medicines | 471.64 Bn | 466.85 Bn | 1.35 Bn | 249.90 Mn |
| 5 | Vertex Pharmaceuticals | 121.72 Bn | 114.47 Bn | 2.59 Bn | 1.14 Bn |
| 6 | Regeneron Pharmaceuticals | 68.28 Bn | 59.52 Bn | 3.31 Bn | 642.90 Mn |
| 7 | Belite Bio | 61.40 Bn | 61.40 Bn | - | -32.68 Mn |
| 8 | Argenx Se | 56.94 Bn | 56.94 Bn | 1.18 Bn | 394.00 Mn |
| 9 | Revolution Medicines | 37.37 Bn | 37.37 Bn | - | -445.22 Mn |
| 10 | Taysha Gene Therapies | 2.01 Bn | 2.01 Bn | - | -43.49 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -43.49 Mn |
| Dec 31, 2025 | -28.30 Mn |
| Sep 30, 2025 | -34.02 Mn |
| Jun 30, 2025 | -26.75 Mn |
| Mar 31, 2025 | -21.42 Mn |
| Dec 31, 2024 | -19.93 Mn |
| Sep 30, 2024 | -25.90 Mn |
| Jun 30, 2024 | -21.30 Mn |
| Mar 31, 2024 | -24.33 Mn |
| Dec 31, 2023 | -16.25 Mn |
| Sep 30, 2023 | -16.25 Mn |
| Jun 30, 2023 | -23.38 Mn |
| Mar 31, 2023 | -16.56 Mn |
| Dec 31, 2022 | -53.97 Mn |
| Sep 30, 2022 | -25.46 Mn |
| Jun 30, 2022 | -33.37 Mn |
| Mar 31, 2022 | -49.65 Mn |
| Dec 31, 2021 | -49.72 Mn |
| Sep 30, 2021 | -50.68 Mn |
| Jun 30, 2021 | -40.77 Mn |