Taysha Gene Therapies (TSHA) EBITDA (2020 - 2026)
Taysha Gene Therapies' (TSHA) quarterly EBITDA came in at -$43.5 million in Q1 2026, down 103.01% year-on-year from $1.4 billion in Q1 2025, and down 53.66% quarter-over-quarter from -$28.3 million in Q4 2025.
Taysha Gene Therapies (TSHA) EBITDA (2020 - 2026) Analysis & Trends
Taysha Gene Therapies has disclosed EBITDA across 7 years of filings, most recently posting -$43.5 million for Q1 2026.
- EBITDA for Q1 2026 came in at -$43.5 million, down 103.01% year-over-year; the trailing twelve-month figure through Mar 2026 was -$132.6 million (down 49.7% YoY), and the FY2025 annual result was -$110.5 million, down 20.82% from the prior year.
- EBITDA came in at -$43.5 million for Q1 2026 at Taysha Gene Therapies, down from -$28.3 million in the prior quarter.
- In the past five years, EBITDA ranged from a high of -$16.2 million in Q4 2023 to a low of -$54.0 million in Q4 2022.
- The 5-year median for EBITDA is -$25.5 million (2022), against an average of -$28.3 million.
- Across the five-year window, EBITDA soared 69.9% in 2023 and tumbled 103.01% in 2026, its largest moves.
- Taysha Gene Therapies' EBITDA stood at -$54.0 million in 2022, then soared by 69.9% to -$16.2 million in 2023, then slipped by 22.69% to -$19.9 million in 2024, then tumbled by 41.98% to -$28.3 million in 2025, then slumped by 53.66% to -$43.5 million in 2026.
- The last three EBITDA figures came in at -$43.5 million (Q1 2026), -$28.3 million (Q4 2025), and -$34.0 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | -26.92 Mn |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | -13.63 Mn |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -19.70 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | -3.82 Mn |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | -14.44 Mn |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | -752,618.00 |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 1.14 Bn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | -65.83 Mn |
| 10 | Taysha Gene Therapies | 2.36 Bn | 2.36 Bn | - | -43.49 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -43.49 Mn |
| Dec 31, 2025 | -28.30 Mn |
| Sep 30, 2025 | -34.02 Mn |
| Jun 30, 2025 | -26.75 Mn |
| Mar 31, 2025 | -21.42 Mn |
| Dec 31, 2024 | -19.93 Mn |
| Sep 30, 2024 | -25.90 Mn |
| Jun 30, 2024 | -21.30 Mn |
| Mar 31, 2024 | -24.33 Mn |
| Dec 31, 2023 | -16.25 Mn |
| Sep 30, 2023 | -16.25 Mn |
| Jun 30, 2023 | -23.38 Mn |
| Mar 31, 2023 | -16.56 Mn |
| Dec 31, 2022 | -53.97 Mn |
| Sep 30, 2022 | -25.46 Mn |
| Jun 30, 2022 | -33.37 Mn |
| Mar 31, 2022 | -49.65 Mn |
| Dec 31, 2021 | -49.72 Mn |
| Sep 30, 2021 | -50.68 Mn |
| Jun 30, 2021 | -40.77 Mn |