Taysha Gene Therapies (TSHA) EBT Margin (2023 - 2025)

Taysha Gene Therapies (TSHA) posted EBT Margin of 2099.17% for Q4 2025, up 18.52% sequentially from 2576.33% in Q2 2025, and down 94022.0% YoY from N/an in Q4 2024.

Taysha Gene Therapies (TSHA) EBT Margin (2023 - 2025) Analysis & Trends

Taysha Gene Therapies has reported EBT Margin for 3 years, with the latest figure at 2099.17% in Q4 2025.

  • Quarterly EBT Margin fell 94022.0% year-over-year to 2099.17% in Q4 2025, while the trailing twelve-month figure through Mar 2026 was 7401.81% (down 554193.0% YoY) and the FY2025 annual result came in at 3326.38%, down 94247.0% from the prior year.
  • EBT Margin rose to 2099.17% in Q4 2025 per TSHA's latest filing, from 2576.33% in the prior quarter.
  • Over five years, EBT Margin peaked at 434.46% in Q4 2023 and troughed at 2957.21% in Q3 2024.
  • A 3-year average of 1605.98% and a median of 1242.14% in 2025 frame the typical range for EBT Margin.
  • The sharpest annual moves came in 2024 and 2025: EBT Margin plunged 240863 bps in 2024, then jumped 7250 bps in 2025.
  • Over 3 years, EBT Margin stood at 434.46% in 2023, then sank by 167 bps to 1158.95% in 2024, then sank by 81 bps to 2099.17% in 2025.
  • According to Business Quant data, EBT Margin over the past three periods registered 2099.17%, 2576.33%, and 1242.14% for Q4 2025, Q2 2025, and Q1 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBT Margin (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 41.75%
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 35.61%
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 34.77%
4 Revolution Medicines 43.64 Bn 43.64 Bn - -
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 18.33%
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -94.22%
7 Royalty Pharma 33.72 Bn 35.84 Bn - 12.09%
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 13.77%
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -2.67%
10 Taysha Gene Therapies 1.94 Bn 1.94 Bn - -

Historic Data

Download Data
DateValue
Dec 31, 2025 -2,099.17%
Jun 30, 2025 -2,576.33%
Mar 31, 2025 -1,242.14%
Dec 31, 2024 -1,158.95%
Sep 30, 2024 -2,957.21%
Jun 30, 2024 -2,648.83%
Mar 31, 2024 -1,082.56%
Dec 31, 2023 -434.46%
Sep 30, 2023 -548.59%
Jun 30, 2023 -2,318.62%
Mar 31, 2023 -598.90%