Taysha Gene Therapies (TSHA) EBT Margin (2023 - 2025)

Taysha Gene Therapies (TSHA) reported EBT Margin of 2099.17% for Q4 2025, down 138928.0% on a YoY basis from N/an in Q4 2024, and up 18.52% sequentially from 2576.33% in Q2 2025.

Taysha Gene Therapies (TSHA) EBT Margin (2023 - 2025) Analysis & Trends

Taysha Gene Therapies (TSHA) has 3 years of EBT Margin data on file, last reported at 2099.17% in Q4 2025.

  • For the quarter ending Q4 2025, EBT Margin fell 138928.0% year-over-year to 2099.17%; the trailing twelve-month figure through Mar 2026 stood at 7401.81% (down 566762.0% YoY), and the FY2025 full-year result was 3326.38%, down 94247.0% from the prior year.
  • EBT Margin rose to 2099.17% in Q4 2025, from 2576.33% in the prior quarter.
  • In the past five years, EBT Margin ranged from a high of 433.19% in Q4 2023 to a low of 2957.21% in Q3 2024.
  • A 3-year average of 1565.04% and a median of 1242.14% in 2025 frame the typical range for EBT Margin.
  • Across the five-year window, EBT Margin slumped 240863 bps in 2024 and surged 7250 bps in 2025, its largest moves.
  • Tracing TSHA's EBT Margin over 3 years: stood at 433.19% in 2023, then sank by 64 bps to 709.89% in 2024, then tumbled by 196 bps to 2099.17% in 2025.
  • Business Quant data shows TSHA's EBT Margin at 2099.17% in Q4 2025, 2576.33% in Q2 2025, and 1242.14% in Q1 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBT Margin (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 17.13%
4 NuCana 279.75 Bn 279.75 Bn - -
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 41.95%
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 23.05%
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 34.77%
9 Revolution Medicines 37.78 Bn 37.78 Bn - -
10 Taysha Gene Therapies 2.14 Bn 2.14 Bn - -

Historic Data

Download Data
DateValue
Dec 31, 2025 -2,099.17%
Jun 30, 2025 -2,576.33%
Mar 31, 2025 -1,242.14%
Dec 31, 2024 -709.89%
Sep 30, 2024 -2,957.21%
Jun 30, 2024 -2,648.83%
Mar 31, 2024 -1,082.56%
Dec 31, 2023 -433.19%
Sep 30, 2023 -548.59%
Jun 30, 2023 -2,318.62%
Mar 31, 2023 -598.90%