Taysha Gene Therapies (TSHA) Enterprise Value (2020 - 2026)

Taysha Gene Therapies' (TSHA) quarterly Enterprise Value came in at -$277.0 million in Q1 2026, down 136.69% year-on-year from $755.1 million in Q1 2025, and up 13.49% quarter-over-quarter from -$320.2 million in Q4 2025.

Taysha Gene Therapies (TSHA) Enterprise Value (2020 - 2026) Analysis & Trends

Taysha Gene Therapies has disclosed Enterprise Value across 7 years of filings, most recently posting -$277.0 million for Q1 2026.

  • Enterprise Value for Q1 2026 came in at -$277.0 million, down 136.69% year-over-year; the trailing twelve-month figure through Mar 2026 was -$277.0 million (down 136.69% YoY), and the FY2025 annual result was -$320.2 million, down 130.79% from the prior year.
  • Enterprise Value came in at -$277.0 million for Q1 2026 at Taysha Gene Therapies, up from -$320.2 million in the prior quarter.
  • In the past five years, Enterprise Value ranged from a high of -$34.3 million in Q3 2022 to a low of -$320.2 million in Q4 2025.
  • The 5-year median for Enterprise Value is -$140.8 million (2023), against an average of -$158.6 million.
  • Across the five-year window, Enterprise Value surged 81.83% in 2022 and sank 378.86% in 2023, its largest moves.
  • Taysha Gene Therapies' Enterprise Value stood at -$34.3 million in 2022, then sank by 316.4% to -$142.8 million in 2023, then gained by 2.87% to -$138.7 million in 2024, then sank by 130.79% to -$320.2 million in 2025, then increased by 13.49% to -$277.0 million in 2026.
  • The last three Enterprise Value figures came in at -$277.0 million (Q1 2026), -$320.2 million (Q4 2025), and -$297.8 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Enterprise Value (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -32.30 Mn
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -4.14 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -286.70 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -18.44 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -2.77 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -7.20 Mn
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn -7.25 Bn
9 Abivax 91.96 Bn 91.96 Bn - -584.73 Mn
10 Taysha Gene Therapies 2.36 Bn 2.36 Bn - -277.03 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -277.03 Mn
Dec 31, 2025 -320.22 Mn
Sep 30, 2025 -297.79 Mn
Jun 30, 2025 -313.21 Mn
Mar 31, 2025 -117.04 Mn
Dec 31, 2024 -138.75 Mn
Sep 30, 2024 -158.14 Mn
Jun 30, 2024 -173.19 Mn
Mar 31, 2024 -124.43 Mn
Dec 31, 2023 -142.85 Mn
Sep 30, 2023 -164.28 Mn
Jun 30, 2023 -45.08 Mn
Mar 31, 2023 -63.43 Mn
Sep 30, 2022 -34.31 Mn
Jun 30, 2022 -68.88 Mn
Mar 31, 2022 -99.27 Mn
Dec 31, 2021 -151.74 Mn
Sep 30, 2021 -188.79 Mn
Jun 30, 2021 -197.37 Mn
Mar 31, 2021 -228.68 Mn