Taysha Gene Therapies (TSHA) Enterprise Value (2020 - 2026)

Taysha Gene Therapies (TSHA) reported Enterprise Value of -$277.0 million for Q1 2026, down 136.71% on a YoY basis from $754.7 million in Q1 2025, and up 13.48% sequentially from -$320.2 million in Q4 2025.

Taysha Gene Therapies (TSHA) Enterprise Value (2020 - 2026) Analysis & Trends

Taysha Gene Therapies (TSHA) has 7 years of Enterprise Value data on file, last reported at -$277.0 million in Q1 2026.

  • For the quarter ending Q1 2026, Enterprise Value fell 136.71% year-over-year to -$277.0 million; the trailing twelve-month figure through Mar 2026 stood at -$277.0 million (down 136.71% YoY), and the FY2025 full-year result was -$320.2 million, down 129.57% from the prior year.
  • Enterprise Value advanced to -$277.0 million in Q1 2026, from -$320.2 million in the prior quarter.
  • In the past five years, Enterprise Value ranged from a high of -$36.9 million in Q3 2022 to a low of -$320.2 million in Q4 2025.
  • A 5-year average of -$158.8 million and a median of -$141.9 million in 2023 frame the typical range for Enterprise Value.
  • Across the five-year window, Enterprise Value surged 80.7% in 2022 and tumbled 344.68% in 2023, its largest moves.
  • Tracing TSHA's Enterprise Value over 5 years: stood at -$36.9 million in 2022, then plunged by 290.84% to -$144.4 million in 2023, then gained by 3.4% to -$139.5 million in 2024, then plunged by 129.57% to -$320.2 million in 2025, then rose by 13.48% to -$277.0 million in 2026.
  • Business Quant data shows TSHA's Enterprise Value at -$277.0 million in Q1 2026, -$320.2 million in Q4 2025, and -$297.8 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Enterprise Value (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -283.54 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -61.40 Mn
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn -4.79 Bn
4 NuCana 279.75 Bn 279.75 Bn - -32.26 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn -7.25 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn -8.75 Bn
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn -5.18 Bn
9 Revolution Medicines 37.78 Bn 37.78 Bn - -1.91 Bn
10 Taysha Gene Therapies 2.14 Bn 2.14 Bn - -277.05 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -277.05 Mn
Dec 31, 2025 -320.22 Mn
Sep 30, 2025 -297.79 Mn
Jun 30, 2025 -313.21 Mn
Mar 31, 2025 -117.04 Mn
Dec 31, 2024 -139.49 Mn
Sep 30, 2024 -158.14 Mn
Jun 30, 2024 -173.19 Mn
Mar 31, 2024 -124.43 Mn
Dec 31, 2023 -144.39 Mn
Sep 30, 2023 -164.28 Mn
Jun 30, 2023 -45.08 Mn
Mar 31, 2023 -63.43 Mn
Sep 30, 2022 -36.94 Mn
Jun 30, 2022 -66.24 Mn
Mar 31, 2022 -99.27 Mn
Dec 31, 2021 -151.74 Mn
Sep 30, 2021 -191.41 Mn
Jun 30, 2021 -197.37 Mn
Mar 31, 2021 -228.68 Mn