Taysha Gene Therapies (TSHA) Enterprise Value (2020 - 2026)
Taysha Gene Therapies' (TSHA) quarterly Enterprise Value came in at -$277.0 million in Q1 2026, down 136.69% year-on-year from $755.1 million in Q1 2025, and up 13.49% quarter-over-quarter from -$320.2 million in Q4 2025.
Taysha Gene Therapies (TSHA) Enterprise Value (2020 - 2026) Analysis & Trends
Taysha Gene Therapies has disclosed Enterprise Value across 7 years of filings, most recently posting -$277.0 million for Q1 2026.
- Enterprise Value for Q1 2026 came in at -$277.0 million, down 136.69% year-over-year; the trailing twelve-month figure through Mar 2026 was -$277.0 million (down 136.69% YoY), and the FY2025 annual result was -$320.2 million, down 130.79% from the prior year.
- Enterprise Value came in at -$277.0 million for Q1 2026 at Taysha Gene Therapies, up from -$320.2 million in the prior quarter.
- In the past five years, Enterprise Value ranged from a high of -$34.3 million in Q3 2022 to a low of -$320.2 million in Q4 2025.
- The 5-year median for Enterprise Value is -$140.8 million (2023), against an average of -$158.6 million.
- Across the five-year window, Enterprise Value surged 81.83% in 2022 and sank 378.86% in 2023, its largest moves.
- Taysha Gene Therapies' Enterprise Value stood at -$34.3 million in 2022, then sank by 316.4% to -$142.8 million in 2023, then gained by 2.87% to -$138.7 million in 2024, then sank by 130.79% to -$320.2 million in 2025, then increased by 13.49% to -$277.0 million in 2026.
- The last three Enterprise Value figures came in at -$277.0 million (Q1 2026), -$320.2 million (Q4 2025), and -$297.8 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Enterprise Value (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | -32.30 Mn |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | -4.14 Mn |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -286.70 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | -18.44 Mn |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | -2.77 Mn |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | -7.20 Mn |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | -7.25 Bn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | -584.73 Mn |
| 10 | Taysha Gene Therapies | 2.36 Bn | 2.36 Bn | - | -277.03 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -277.03 Mn |
| Dec 31, 2025 | -320.22 Mn |
| Sep 30, 2025 | -297.79 Mn |
| Jun 30, 2025 | -313.21 Mn |
| Mar 31, 2025 | -117.04 Mn |
| Dec 31, 2024 | -138.75 Mn |
| Sep 30, 2024 | -158.14 Mn |
| Jun 30, 2024 | -173.19 Mn |
| Mar 31, 2024 | -124.43 Mn |
| Dec 31, 2023 | -142.85 Mn |
| Sep 30, 2023 | -164.28 Mn |
| Jun 30, 2023 | -45.08 Mn |
| Mar 31, 2023 | -63.43 Mn |
| Sep 30, 2022 | -34.31 Mn |
| Jun 30, 2022 | -68.88 Mn |
| Mar 31, 2022 | -99.27 Mn |
| Dec 31, 2021 | -151.74 Mn |
| Sep 30, 2021 | -188.79 Mn |
| Jun 30, 2021 | -197.37 Mn |
| Mar 31, 2021 | -228.68 Mn |