Taysha Gene Therapies (TSHA) Change in Cash (2020 - 2026)
Taysha Gene Therapies (TSHA) posted Change in Cash of -$43.2 million for Q1 2026, down 291.22% sequentially from $22.6 million in Q4 2025, and down 92.45% YoY from -$571.9 million in Q1 2025.
Analysis
Taysha Gene Therapies (TSHA) Change in Cash (2020 - 2026) Analysis & Trends
Taysha Gene Therapies has reported Change in Cash for 7 years, with the latest figure at -$43.2 million in Q1 2026.
- Quarterly Change in Cash fell 92.45% year-over-year to -$43.2 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $160.1 million (up 2267.96% YoY) and the FY2025 annual result came in at $180.9 million, up 3788.72% from the prior year.
- Change in Cash fell to -$43.2 million in Q1 2026 per TSHA's latest filing, from $22.6 million in the prior quarter.
- Over five years, Change in Cash peaked at $196.2 million in Q2 2025 and troughed at -$52.5 million in Q1 2022.
- A 5-year average of $7.5 million and a median of -$18.7 million in 2024 frame the typical range for Change in Cash.
- The sharpest annual moves came in 2022 and 2023: Change in Cash slumped 436.06% in 2022, then surged 473.27% in 2023.
- Over 5 years, Change in Cash stood at $53.6 million in 2022, then slumped by 138.03% to -$20.4 million in 2023, then climbed by 8.46% to -$18.7 million in 2024, then jumped by 221.1% to $22.6 million in 2025, then sank by 291.22% to -$43.2 million in 2026.
- According to Business Quant data, Change in Cash over the past three periods registered -$43.2 million, $22.6 million, and -$15.4 million for Q1 2026, Q4 2025, and Q3 2025 respectively.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Change in Cash (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 138.47 Bn | 130.62 Bn | 2.84 Bn | 649.20 Mn |
| 2 | Regeneron Pharmaceuticals | 85.18 Bn | 77.19 Bn | 3.93 Bn | -504.60 Mn |
| 3 | Argenx Se | 63.38 Bn | 58.19 Bn | 1.37 Bn | - |
| 4 | Moderna | 58.09 Bn | 52.95 Bn | 52.00 Mn | -185.00 Mn |
| 5 | Revolution Medicines | 44.33 Bn | 44.33 Bn | - | 374.50 Mn |
| 6 | BeOne Medicines | 40.02 Bn | 34.92 Bn | 1.53 Bn | 427.25 Mn |
| 7 | Alnylam Pharmaceuticals | 35.57 Bn | 32.27 Bn | 992.69 Mn | -2.94 Mn |
| 8 | Royalty Pharma | 28.45 Bn | 27.61 Bn | - | 225.59 Mn |
| 9 | Insmed | 27.48 Bn | 26.32 Bn | 358.27 Mn | -37.42 Mn |
| 10 | Taysha Gene Therapies | 2.06 Bn | 2.06 Bn | - | 176.23 Mn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 176.23 Mn |
| Mar 31, 2026 | -43.19 Mn |
| Dec 31, 2025 | 22.59 Mn |
| Sep 30, 2025 | -15.42 Mn |
| Jun 30, 2025 | 196.17 Mn |
| Mar 31, 2025 | -22.44 Mn |
| Dec 31, 2024 | -18.65 Mn |
| Sep 30, 2024 | -15.06 Mn |
| Jun 30, 2024 | 48.76 Mn |
| Mar 31, 2024 | -19.96 Mn |
| Dec 31, 2023 | -20.38 Mn |
| Sep 30, 2023 | 119.20 Mn |
| Jun 30, 2023 | -18.34 Mn |
| Mar 31, 2023 | -24.46 Mn |
| Dec 31, 2022 | 53.57 Mn |
| Sep 30, 2022 | -31.93 Mn |
| Jun 30, 2022 | -30.39 Mn |
| Mar 31, 2022 | -52.47 Mn |
| Dec 31, 2021 | -39.67 Mn |
| Sep 30, 2021 | -5.96 Mn |