Taysha Gene Therapies (TSHA) Change in Cash (2020 - 2026)

Taysha Gene Therapies' (TSHA) quarterly Change in Cash came in at -$43.2 million in Q1 2026, down 92.45% year-on-year from -$571.9 million in Q1 2025, and down 291.22% quarter-over-quarter from $22.6 million in Q4 2025.

Taysha Gene Therapies (TSHA) Change in Cash (2020 - 2026) Analysis & Trends

Taysha Gene Therapies has disclosed Change in Cash across 7 years of filings, most recently posting -$43.2 million for Q1 2026.

  • Change in Cash for Q1 2026 came in at -$43.2 million, down 92.45% year-over-year; the trailing twelve-month figure through Mar 2026 was $160.1 million (up 2267.96% YoY), and the FY2025 annual result was $180.9 million, up 3788.72% from the prior year.
  • Change in Cash came in at -$43.2 million for Q1 2026 at Taysha Gene Therapies, down from $22.6 million in the prior quarter.
  • In the past five years, Change in Cash ranged from a high of $196.2 million in Q2 2025 to a low of -$52.5 million in Q1 2022.
  • The 5-year median for Change in Cash is -$18.7 million (2024), against an average of $7.5 million.
  • Across the five-year window, Change in Cash slumped 436.06% in 2022 and soared 473.27% in 2023, its largest moves.
  • Taysha Gene Therapies' Change in Cash stood at $53.6 million in 2022, then slumped by 138.03% to -$20.4 million in 2023, then gained by 8.46% to -$18.7 million in 2024, then surged by 221.1% to $22.6 million in 2025, then sank by 291.22% to -$43.2 million in 2026.
  • The last three Change in Cash figures came in at -$43.2 million (Q1 2026), $22.6 million (Q4 2025), and -$15.4 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Change in Cash (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - 2.44 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 623.00 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -2.44 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 417.10 Mn
9 Abivax 91.96 Bn 91.96 Bn - -45.97 Mn
10 Taysha Gene Therapies 2.36 Bn 2.36 Bn - -43.19 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -43.19 Mn
Dec 31, 2025 22.59 Mn
Sep 30, 2025 -15.42 Mn
Jun 30, 2025 196.17 Mn
Mar 31, 2025 -22.44 Mn
Dec 31, 2024 -18.65 Mn
Sep 30, 2024 -15.06 Mn
Jun 30, 2024 48.76 Mn
Mar 31, 2024 -19.96 Mn
Dec 31, 2023 -20.38 Mn
Sep 30, 2023 119.20 Mn
Jun 30, 2023 -18.34 Mn
Mar 31, 2023 -24.46 Mn
Dec 31, 2022 53.57 Mn
Sep 30, 2022 -31.93 Mn
Jun 30, 2022 -30.39 Mn
Mar 31, 2022 -52.47 Mn
Dec 31, 2021 -39.67 Mn
Sep 30, 2021 -5.96 Mn
Jun 30, 2021 -31.31 Mn