Taysha Gene Therapies (TSHA) Change in Cash (2020 - 2026)

Taysha Gene Therapies (TSHA) reported Change in Cash of -$43.2 million for Q1 2026, down 92.45% on a YoY basis from -$571.9 million in Q1 2025, and down 291.22% sequentially from $22.6 million in Q4 2025.

Taysha Gene Therapies (TSHA) Change in Cash (2020 - 2026) Analysis & Trends

Taysha Gene Therapies (TSHA) has 7 years of Change in Cash data on file, last reported at -$43.2 million in Q1 2026.

  • For the quarter ending Q1 2026, Change in Cash fell 92.45% year-over-year to -$43.2 million; the trailing twelve-month figure through Mar 2026 stood at $160.1 million (up 2267.96% YoY), and the FY2025 full-year result was $180.9 million, up 3788.72% from the prior year.
  • Change in Cash fell to -$43.2 million in Q1 2026, from $22.6 million in the prior quarter.
  • In the past five years, Change in Cash ranged from a high of $196.2 million in Q2 2025 to a low of -$52.5 million in Q1 2022.
  • A 5-year average of $7.5 million and a median of -$18.7 million in 2024 frame the typical range for Change in Cash.
  • Across the five-year window, Change in Cash plunged 436.06% in 2022 and soared 473.27% in 2023, its largest moves.
  • Tracing TSHA's Change in Cash over 5 years: stood at $53.6 million in 2022, then tumbled by 138.03% to -$20.4 million in 2023, then rose by 8.46% to -$18.7 million in 2024, then jumped by 221.1% to $22.6 million in 2025, then slumped by 291.22% to -$43.2 million in 2026.
  • Business Quant data shows TSHA's Change in Cash at -$43.2 million in Q1 2026, $22.6 million in Q4 2025, and -$15.4 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Change in Cash (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -22.03 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 243.78 Mn
4 NuCana 279.75 Bn 279.75 Bn - -1.34 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 417.10 Mn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn -153.10 Mn
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn -
9 Revolution Medicines 37.78 Bn 37.78 Bn - 57.19 Mn
10 Taysha Gene Therapies 2.14 Bn 2.14 Bn - -43.19 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -43.19 Mn
Dec 31, 2025 22.59 Mn
Sep 30, 2025 -15.42 Mn
Jun 30, 2025 196.17 Mn
Mar 31, 2025 -22.44 Mn
Dec 31, 2024 -18.65 Mn
Sep 30, 2024 -15.06 Mn
Jun 30, 2024 48.76 Mn
Mar 31, 2024 -19.96 Mn
Dec 31, 2023 -20.38 Mn
Sep 30, 2023 119.20 Mn
Jun 30, 2023 -18.34 Mn
Mar 31, 2023 -24.46 Mn
Dec 31, 2022 53.57 Mn
Sep 30, 2022 -31.93 Mn
Jun 30, 2022 -30.39 Mn
Mar 31, 2022 -52.47 Mn
Dec 31, 2021 -39.67 Mn
Sep 30, 2021 -5.96 Mn
Jun 30, 2021 -31.31 Mn