Taysha Gene Therapies (TSHA) Net Margin (2023 - 2025)
Taysha Gene Therapies' (TSHA) quarterly Net Margin came in at 2297.94% in Q4 2025, down 136891.0% year-on-year from N/an in Q4 2024, and down 69.77% quarter-over-quarter from 1353.58% in Q2 2025.
Taysha Gene Therapies (TSHA) Net Margin (2023 - 2025) Analysis & Trends
Taysha Gene Therapies has disclosed Net Margin across 3 years of filings, most recently posting 2297.94% for Q4 2025.
- Net Margin for Q4 2025 came in at 2297.94%, down 136891.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 4061.16% (down 286008.0% YoY), and the FY2025 annual result was 1981.73%, down 91011.0% from the prior year.
- Net Margin came in at 2297.94% for Q4 2025 at Taysha Gene Therapies, down from 1353.58% in the prior quarter.
- In the past five years, Net Margin ranged from a high of 1324.67% in Q4 2023 to a low of 2467.07% in Q3 2023.
- The 3-year median for Net Margin is 1027.06% (2023), against an average of 1097.69%.
- Peak annual rise in Net Margin reached 103955 bps in 2024, while the deepest fall reached 225370 bps in 2024.
- Taysha Gene Therapies' Net Margin stood at 1324.67% in 2023, then tumbled by 170 bps to 929.03% in 2024, then plunged by 147 bps to 2297.94% in 2025.
- The last three Net Margin figures came in at 2297.94% (Q4 2025), 1353.58% (Q2 2025), and 935.23% (Q1 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | - |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | 0.82% |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | - |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 34.53% |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | - |
| 10 | Taysha Gene Therapies | 2.36 Bn | 2.36 Bn | - | - |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -2,297.94% |
| Jun 30, 2025 | -1,353.58% |
| Mar 31, 2025 | -935.23% |
| Dec 31, 2024 | -929.03% |
| Sep 30, 2024 | -1,427.52% |
| Jun 30, 2024 | -1,882.01% |
| Mar 31, 2024 | -705.39% |
| Dec 31, 2023 | 1,324.67% |
| Sep 30, 2023 | -2,467.07% |
| Jun 30, 2023 | -1,027.06% |
| Mar 31, 2023 | -374.46% |