Taysha Gene Therapies (TSHA) Net Margin (2023 - 2025)

Taysha Gene Therapies' (TSHA) quarterly Net Margin came in at 2297.94% in Q4 2025, down 136891.0% year-on-year from N/an in Q4 2024, and down 69.77% quarter-over-quarter from 1353.58% in Q2 2025.

Taysha Gene Therapies (TSHA) Net Margin (2023 - 2025) Analysis & Trends

Taysha Gene Therapies has disclosed Net Margin across 3 years of filings, most recently posting 2297.94% for Q4 2025.

  • Net Margin for Q4 2025 came in at 2297.94%, down 136891.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 4061.16% (down 286008.0% YoY), and the FY2025 annual result was 1981.73%, down 91011.0% from the prior year.
  • Net Margin came in at 2297.94% for Q4 2025 at Taysha Gene Therapies, down from 1353.58% in the prior quarter.
  • In the past five years, Net Margin ranged from a high of 1324.67% in Q4 2023 to a low of 2467.07% in Q3 2023.
  • The 3-year median for Net Margin is 1027.06% (2023), against an average of 1097.69%.
  • Peak annual rise in Net Margin reached 103955 bps in 2024, while the deepest fall reached 225370 bps in 2024.
  • Taysha Gene Therapies' Net Margin stood at 1324.67% in 2023, then tumbled by 170 bps to 929.03% in 2024, then plunged by 147 bps to 2297.94% in 2025.
  • The last three Net Margin figures came in at 2297.94% (Q4 2025), 1353.58% (Q2 2025), and 935.23% (Q1 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Margin (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 0.82%
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 34.53%
9 Abivax 91.96 Bn 91.96 Bn - -
10 Taysha Gene Therapies 2.36 Bn 2.36 Bn - -

Historic Data

Download Data
DateValue
Dec 31, 2025 -2,297.94%
Jun 30, 2025 -1,353.58%
Mar 31, 2025 -935.23%
Dec 31, 2024 -929.03%
Sep 30, 2024 -1,427.52%
Jun 30, 2024 -1,882.01%
Mar 31, 2024 -705.39%
Dec 31, 2023 1,324.67%
Sep 30, 2023 -2,467.07%
Jun 30, 2023 -1,027.06%
Mar 31, 2023 -374.46%