Taysha Gene Therapies (TSHA) Net Margin (2023 - 2025)
Taysha Gene Therapies (TSHA) reported Net Margin of 2297.94% for Q4 2025, down 136891.0% on a YoY basis from N/an in Q4 2024, and down 69.77% sequentially from 1353.58% in Q2 2025.
Taysha Gene Therapies (TSHA) Net Margin (2023 - 2025) Analysis & Trends
Taysha Gene Therapies (TSHA) has 3 years of Net Margin data on file, last reported at 2297.94% in Q4 2025.
- For the quarter ending Q4 2025, Net Margin fell 136891.0% year-over-year to 2297.94%; the trailing twelve-month figure through Mar 2026 stood at 4061.16% (down 286008.0% YoY), and the FY2025 full-year result was 1981.73%, down 91011.0% from the prior year.
- Net Margin eased to 2297.94% in Q4 2025, from 1353.58% in the prior quarter.
- In the past five years, Net Margin ranged from a high of 1324.67% in Q4 2023 to a low of 2467.07% in Q3 2023.
- A 3-year average of 1097.69% and a median of 1027.06% in 2023 frame the typical range for Net Margin.
- Peak annual rise in Net Margin reached 103955 bps in 2024, while the deepest fall reached 225370 bps in 2024.
- Tracing TSHA's Net Margin over 3 years: stood at 1324.67% in 2023, then plunged by 170 bps to 929.03% in 2024, then sank by 147 bps to 2297.94% in 2025.
- Business Quant data shows TSHA's Net Margin at 2297.94% in Q4 2025, 1353.58% in Q2 2025, and 935.23% in Q1 2025.
Powered by 
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | - |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | - |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | 15.02% |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | - |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | 34.53% |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | 20.17% |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | - |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | 30.33% |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | - |
| 10 | Taysha Gene Therapies | 2.14 Bn | 2.14 Bn | - | - |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -2,297.94% |
| Jun 30, 2025 | -1,353.58% |
| Mar 31, 2025 | -935.23% |
| Dec 31, 2024 | -929.03% |
| Sep 30, 2024 | -1,427.52% |
| Jun 30, 2024 | -1,882.01% |
| Mar 31, 2024 | -705.39% |
| Dec 31, 2023 | 1,324.67% |
| Sep 30, 2023 | -2,467.07% |
| Jun 30, 2023 | -1,027.06% |
| Mar 31, 2023 | -374.46% |