Taysha Gene Therapies TSHA Institutional Ownership

NASDAQ TSHA

$5.61 +0.04 (+0.72%)

As of: Sep 4, 2026 · 3:59 PM EDT

Institutions by Trading Activity

210 Institutions

Increased 141 67.1%

Unchanged 26 12.4%

Reduced 43 20.5%

Ownership Statistics

13F · as of 30 Jun, 2026

Institutional Ownership

81.77%

▲+9.26 pp QoQ

Shares Held by Institutions

301.76Mn

of 369.04Mn outstanding

▲+15.42% QoQ

Shares Outstanding

369.04Mn

67.28Mn held outside 13F filers

Institutional Investors

210

filed 13F for Jun 2026

▲+19 vs prior quarter

Net Shares Added (QoQ)

+40.32Mn

accumulated since last quarter

Value of Holdings

$1.68Bn

reported market value

Shares Owned by Institutions

Shares held % of outstanding

Latest —

Average ownership —

Peak ownership —

Shares Purchased/Sold by Institutions

Accumulated Distributed

Latest quarter —

Net over range —

Accumulating quarters —

Ownership Summary

Quarter ending 30 Jun, 2026

Taysha Gene Therapies, Inc. (NASDAQ:TSHA) appears in 210 institutional 13F filings for the quarter ending June 2026.

Their combined ownership stood at 81.8% of outstanding shares in June 2026, up from 72.5% in March 2026.
They increased total shares held in TSHA by 15.42% quarter over quarter, and investors in Taysha Gene Therapies increased 41.89% from a year ago.
During the quarter, 141 of these 210 funds increased positions in TSHA, 43 reduced exposure, and 26 held steady.
In total, institutional investors held 301.76Mn shares in Taysha Gene Therapies as of June 2026, up by 40.32Mn shares quarter on quarter, and up 59.93Mn shares year over year.
Avoro Capital Advisors LLC leads ownership in TSHA with 23.89Mn shares as of June 30, 2026, equal to 6.47% of outstanding shares.
The biggest buyers of Taysha Gene Therapies for the quarter ending June 2026 included MPM BioImpact LLC (4.5Mn), WELLINGTON MANAGEMENT GROUP LLP (3.35Mn), Pictet Asset Management Holding SA (2.75Mn), BlackRock, Inc. (2.33Mn), FARALLON CAPITAL MANAGEMENT, L.L.C. (2.25Mn).
The largest sales of TSHA for the quarter ending June 2026 came from SG Americas Securities, LLC (1.97Mn), Morgan Stanley (1.48Mn), Barclays Plc (1.18Mn), MILLENNIUM MANAGEMENT LLC (1.15Mn), FMR LLC (984.84K).
Per Business Quant data, the top 10 holders of Taysha Gene Therapies for the quarter ending June 2026 are Avoro Capital Advisors LLC (23.89Mn), RA CAPITAL MANAGEMENT, L.P. (23.56Mn), Goldman Sachs Group Inc (22.71Mn), BlackRock, Inc. (20.69Mn), Vestal Point Capital, LP (19.42Mn), Morgan Stanley (16.49Mn), RTW INVESTMENTS, LP (13.56Mn), FMR LLC (13.34Mn), VANGUARD CAPITAL MANAGEMENT LLC (12.48Mn), State Street Corp (11.42Mn).

Form 13F Holdings

210 Institutional Holders

Report period 30 Jun, 2026

Total shares held 301.76Mn

Of outstanding 81.77%

#	Institution	CIK	Shares Held	% of Outstanding	Change (QoQ)	Change (%)	Value (USD)
1	Avoro Capital Advisors LLC	0001633313	23,888,888	6.47%	▲2,188,888	+10.09%	$162.68Mn
2	RA CAPITAL MANAGEMENT, L.P.	0001346824	23,555,648	6.38%	0	0.00%	$160.41Mn
3	Goldman Sachs Group Inc	0000886982	22,713,118	6.15%	▲343,473	+1.54%	$154.68Mn
4	BlackRock, Inc.	0002012383	20,691,927	5.61%	▲2,326,319	+12.67%	$140.91Mn
5	Vestal Point Capital, LP	0001974915	19,415,000	5.26%	▲1,415,000	+7.86%	$132.22Mn
6	Morgan Stanley	0000895421	16,487,479	4.47%	▼1,477,892	-8.23%	$112.28Mn
7	RTW INVESTMENTS, LP	0001493215	13,560,258	3.67%	▼119,990	-0.88%	$92.35Mn
8	FMR LLC	0000315066	13,336,413	3.61%	▼984,842	-6.88%	$90.82Mn
9	VANGUARD CAPITAL MANAGEMENT LLC	0002100119	12,478,595	3.38%	▲2,247,093	+21.96%	$84.98Mn
10	State Street Corp	0000093751	11,421,920	3.10%	▲212,842	+1.90%	$77.78Mn
11	Siren, L.L.C.	0002005245	9,846,579	2.67%	▲1,016,666	+11.51%	$67.06Mn
12	Octagon Capital Advisors LP	0001839435	9,693,244	2.63%	▲833,333	+9.41%	$66.01Mn
13	GEODE CAPITAL MANAGEMENT, LLC	0001214717	6,560,394	1.78%	▲1,028,439	+18.59%	$44.69Mn
14	Polar Capital Holdings Plc	0001837309	5,117,133	1.39%	▼537,207	-9.50%	$34.85Mn
15	MPM BioImpact LLC	0001687078	4,500,000	1.22%	▲4,500,000	0.00%	$30.65Mn
16	D. E. Shaw & Co., Inc.	0001009207	4,398,652	1.19%	▼28,649	-0.65%	$29.95Mn
17	BAKER BROS. ADVISORS LP	0001263508	4,004,756	1.09%	0	0.00%	$27.27Mn
18	WELLINGTON MANAGEMENT GROUP LLP	0000902219	3,975,605	1.08%	▲3,349,244	+534.71%	$27.07Mn
19	HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND	0001535845	3,885,501	1.05%	▲1,002,200	+34.76%	$26.46Mn
20	Casdin Capital, LLC	0001534261	3,250,000	0.88%	0	0.00%	$22.13Mn

Showing 1 to 20 of 210 holders