Pyxis Oncology (PYXS) Operating Margin (2024 - 2025)
Pyxis Oncology (PYXS) reported Operating Margin of 165.75% for Q4 2025, up 76.33% quarter-over-quarter from 700.35% in Q2 2025.
Pyxis Oncology (PYXS) Operating Margin (2024 - 2025) Analysis & Trends
Pyxis Oncology (PYXS) has 2 years of Operating Margin data on file, last reported at 165.75% in Q4 2025.
- Operating Margin for Q4 2025 came in at 165.75%, changed N/A year-over-year; the trailing twelve-month figure through Dec 2025 was 609.18% (down 5511.0% YoY), and the FY2025 annual result was 609.18%, down 5511.0% from the prior year.
- Operating Margin climbed to 165.75% in Q4 2025 per PYXS's latest filing, from 700.35% in the prior quarter.
- Over five years, Operating Margin peaked at 34.71% in Q1 2024 and troughed at 700.35% in Q2 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | - |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -6.43% |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | - |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 38.10% |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | - |
| 10 | Pyxis Oncology | 125.84 Mn | 108.95 Mn | 8.65 Mn | -165.75% |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -165.75% |
| Jun 30, 2025 | -700.35% |
| Mar 31, 2024 | -34.71% |