Pfizer (PFE) Operating Margin (2009 - 2026)
Pfizer's Operating Margin came in at 28.37% for Q2 2026, down 6.11 percentage points from 34.48% a year earlier and down 8.67 percentage points from the prior quarter.
Pfizer (PFE) Operating Margin (2009 - 2026) Analysis & Trends
Over the trailing twelve months to Jun 28, 2026, Pfizer reported Operating Margin of 32.02%, up 0.54 percentage points year-over-year; for FY2025, it came in at 33.13%, up 5.14 percentage points from FY2024.
- Operating Margin carries a five-year change of +3.64 percentage points (FY2020 to FY2025).
- Going back by year, Operating Margin was 27.98% in FY2024 (+17.56 pp), 10.42% in FY2023 (-29.46 pp), 39.88% in FY2022 (+7.16 pp) and 32.73% in FY2021 (+3.24 pp).
- The five-year range for quarterly Operating Margin is -20.25% (Q4 2023) to 47.01% (Q2 2022).
- Year-over-year, Operating Margin increased in five of the last seven quarters, with an average year-over-year change of +8.53 percentage points.
- The fastest year-over-year change in Operating Margin over five years came in Q4 2024 (a gain of 41.61 percentage points), and the weakest in Q2 2023 (a drop of 20.79 percentage points).
- Business Quant data shows PFE's Operating Margin at 37.04% (Q1 2026), 24.56% (Q4 2025) and 38.81% (Q3 2025) in the three quarters before Q2 2026.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 645.01 Bn | 563.54 Bn | 17.26 Bn | 28.21% |
| 2 | AbbVie | 465.23 Bn | 438.39 Bn | 12.70 Bn | 37.86% |
| 3 | Merck | 368.40 Bn | 322.83 Bn | 12.21 Bn | -3.52% |
| 4 | Novartis Ag | 278.02 Bn | 233.89 Bn | 11.24 Bn | 32.97% |
| 5 | Astrazeneca | 254.57 Bn | 228.13 Bn | 12.86 Bn | 20.57% |
| 6 | Amgen | 229.02 Bn | 184.42 Bn | 7.24 Bn | 34.95% |
| 7 | Gilead Sciences | 187.74 Bn | 161.85 Bn | 6.22 Bn | -133.21% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 28.37% |
| 9 | Vertex Pharmaceuticals | 133.45 Bn | 105.45 Bn | 2.84 Bn | 37.40% |
| 10 | Bristol Myers Squibb | 128.45 Bn | 79.72 Bn | 9.25 Bn | 2.77% |
Historic Data
| Date | Value |
|---|---|
| Jun 28, 2026 | 28.37% |
| Mar 29, 2026 | 37.04% |
| Dec 31, 2025 | 24.56% |
| Sep 28, 2025 | 38.81% |
| Jun 29, 2025 | 34.48% |
| Mar 30, 2025 | 36.15% |
| Dec 31, 2024 | 21.36% |
| Sep 29, 2024 | 35.50% |
| Jun 30, 2024 | 17.44% |
| Mar 31, 2024 | 36.36% |
| Dec 31, 2023 | -20.25% |
| Jul 2, 2023 | 26.22% |
| Apr 2, 2023 | 41.77% |
| Jul 3, 2022 | 47.01% |
| Apr 3, 2022 | 41.27% |
| Oct 3, 2021 | 32.77% |
| Jul 4, 2021 | 35.70% |
| Apr 4, 2021 | 38.34% |
| Dec 31, 2020 | 18.87% |
| Sep 27, 2020 | 32.28% |
Pfizer Operating Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=operating-margin&ticker=PFE&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "operating-margin", "ticker": "PFE", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=operating-margin&ticker=PFE&period=max&api_key=YOUR_API_KEY");
const data = await res.json();