Pfizer PFE
NYSE PFE
$29.36 +0.12 (+0.41%)
At close: Nov 10, 2026 · 4:00 PM EST

Pfizer (PFE) Operating Margin (2009 - 2026)

Updated

Pfizer's Operating Margin came in at 32.98% for Q3 2026, down 5.83 percentage points from 38.81% a year earlier but up 4.61 percentage points from the prior quarter.

Analysis

Pfizer (PFE) Operating Margin (2009 - 2026) Analysis & Trends

Over the trailing twelve months to Sep 27, 2026, Pfizer reported Operating Margin of 30.49%, down 1.80 percentage points year-over-year; for FY2025, it came in at 33.13%, up 5.14 percentage points from FY2024.

  • Operating Margin carries a five-year change of +3.64 percentage points (FY2020 to FY2025).
  • Going back by year, Operating Margin was 27.98% in FY2024 (+17.56 pp), 10.42% in FY2023 (-29.46 pp), 39.88% in FY2022 (+7.16 pp) and 32.73% in FY2021 (+3.24 pp).
  • The five-year range for quarterly Operating Margin is -20.25% (Q4 2023) to 47.01% (Q2 2022).
  • Year-over-year, Operating Margin increased in five of the last eight quarters, with an average year-over-year change of +6.74 percentage points.
  • The fastest year-over-year change in Operating Margin over five years came in Q3 2024 (a gain of 49.77 percentage points), and the weakest in Q3 2023 (a drop of 59.72 percentage points).
  • Business Quant data shows PFE's Operating Margin at 28.37% (Q2 2026), 37.04% (Q1 2026) and 24.56% (Q4 2025) in the three quarters before Q3 2026.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Operating Margin (Qtr)
1 Eli Lilly 1,348.13 Bn 1,321.74 Bn 20.46 Bn 34.46%
2 Johnson & Johnson 675.90 Bn 595.76 Bn 17.30 Bn 24.35%
3 AbbVie 519.45 Bn 487.50 Bn 13.12 Bn 36.01%
4 Merck 364.95 Bn 327.95 Bn 13.19 Bn 30.74%
5 Novartis Ag 311.58 Bn 285.16 Bn - -
6 Astrazeneca 289.34 Bn 262.94 Bn 13.26 Bn 29.12%
7 Amgen 251.64 Bn 203.30 Bn 7.58 Bn 35.79%
8 Gilead Sciences 212.05 Bn 187.07 Bn 6.73 Bn 41.71%
9 Pfizer 167.35 Bn 115.00 Bn 12.56 Bn 32.98%
10 Vertex Pharmaceuticals 138.90 Bn 106.64 Bn 2.91 Bn 20.72%
Historic Data

Historic Data

Download Data
DateValue
Sep 27, 2026 32.98%
Jun 28, 2026 28.37%
Mar 29, 2026 37.04%
Dec 31, 2025 24.56%
Sep 28, 2025 38.81%
Jun 29, 2025 34.48%
Mar 30, 2025 36.15%
Dec 31, 2024 21.36%
Sep 29, 2024 35.50%
Jun 30, 2024 17.44%
Mar 31, 2024 36.36%
Dec 31, 2023 -20.25%
Oct 1, 2023 -14.27%
Jul 2, 2023 26.22%
Apr 2, 2023 41.77%
Dec 31, 2022 25.59%
Oct 2, 2022 45.45%
Jul 3, 2022 47.01%
Apr 3, 2022 41.27%
Oct 3, 2021 32.77%
API Access

Pfizer Operating Margin API

Pull this series into your own models, spreadsheets and apps with the Business Quant Historical Metrics API. The request below matches the chart above — change the frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.

https://data.businessquant.com/historic?slug=operating-margin&ticker=PFE&period=max&api_key=YOUR_API_KEY