Pfizer (PFE) Operating Margin (2009 - 2026)
Pfizer (PFE) reported Operating Margin of 286.83% for Q1 2026, up 2760.0% year-over-year from 10.03% in Q1 2025, and down 1313.18% on a QoQ basis from 23.64% in Q4 2025.
Pfizer (PFE) has 18 years of Operating Margin data on file, last reported at 286.83% in Q1 2026.
- Quarterly Operating Margin rose 2760.0% year-over-year to 286.83% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 72.46% (down 4104.0% YoY) and the FY2025 annual result came in at 33.13%, up 47426.0% from the prior year.
- Operating Margin declined to 286.83% in Q1 2026 per PFE's latest filing, from 23.64% in the prior quarter.
- Across five years, Operating Margin topped out at 47.01% in Q3 2022 and bottomed at 2483.26% in Q3 2024.
- The 5-year median for Operating Margin is 196.8% (2023), against an average of 341.58%.
- The widest annual swing landed in 2024, when Operating Margin tumbled 164612 bps; it then soared 214196 bps in 2025.
- Tracing PFE's Operating Margin over 5 years: stood at 45.55% in 2022, then sank by 938 bps to 381.77% in 2023, then sank by 550 bps to 2483.26% in 2024, then surged by 101 bps to 23.64% in 2025, then slumped by 1313 bps to 286.83% in 2026.
- Per Business Quant, the three latest PFE Operating Margin figures stand at 286.83% (Q1 2026), 23.64% (Q4 2025), and 341.3% (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Novartis Ag | 107,124,802.25 Bn | 107,124,802.25 Bn | - | - |
| 2 | Eli Lilly | 969.00 Bn | 963.72 Bn | 16.22 Bn | 47.98% |
| 3 | Johnson & Johnson | 539.46 Bn | 517.41 Bn | 15.96 Bn | 26.44% |
| 4 | AbbVie | 376.92 Bn | 367.57 Bn | 10.78 Bn | 26.60% |
| 5 | Merck | 285.00 Bn | 279.35 Bn | 12.09 Bn | -47.46% |
| 6 | Amgen | 177.58 Bn | 165.55 Bn | 5.87 Bn | 30.94% |
| 7 | Gilead Sciences | 163.22 Bn | 155.50 Bn | 5.52 Bn | 37.16% |
| 8 | Pfizer | 145.86 Bn | 133.09 Bn | -1.21 Bn | -286.83% |
| 9 | Bristol Myers Squibb | 111.90 Bn | 101.44 Bn | 8.07 Bn | -1.58% |
| 10 | Gsk | 88.34 Bn | 83.66 Bn | - | - |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 29, 2026 | -286.83% |
| Dec 31, 2025 | 23.64% |
| Sep 28, 2025 | -341.30% |
| Jun 29, 2025 | -322.39% |
| Mar 30, 2025 | -314.43% |
| Sep 29, 2024 | -2,483.26% |
| Jun 30, 2024 | 18.57% |
| Mar 31, 2024 | 36.98% |
| Dec 31, 2023 | -381.77% |
| Oct 1, 2023 | -837.14% |
| Jul 2, 2023 | -172.78% |
| Apr 2, 2023 | -196.80% |
| Oct 2, 2022 | 45.55% |
| Jul 3, 2022 | 47.01% |
| Apr 3, 2022 | 41.27% |
| Oct 3, 2021 | 32.79% |
| Jul 4, 2021 | 35.67% |
| Apr 4, 2021 | 38.38% |
| Sep 27, 2020 | 32.28% |
| Jun 28, 2020 | 30.04% |
| Mar 29, 2020 | 38.57% |
| Sep 29, 2019 | 35.11% |
| Jun 30, 2019 | 41.31% |
| Mar 31, 2019 | 42.94% |
| Dec 31, 2018 | -443.64% |
| Sep 30, 2018 | 38.36% |
| Jul 1, 2018 | 38.37% |
| Apr 1, 2018 | 39.87% |
| Dec 31, 2017 | 75.01% |
| Oct 1, 2017 | 78.55% |
| Jul 2, 2017 | 79.72% |
| Apr 2, 2017 | 81.45% |
| Dec 31, 2016 | 77.44% |
| Oct 2, 2016 | 76.60% |
| Jul 3, 2016 | 75.60% |
| Apr 3, 2016 | 78.66% |
| Dec 31, 2015 | 76.20% |
| Sep 27, 2015 | 81.08% |
| Jun 28, 2015 | 81.04% |
| Mar 29, 2015 | 83.69% |
| Dec 31, 2014 | 23.20% |
| Sep 28, 2014 | 37.65% |
| Jun 29, 2014 | 38.76% |
| Mar 30, 2014 | 40.56% |
| Dec 31, 2013 | 31.79% |
| Sep 29, 2013 | 40.65% |
| Jun 30, 2013 | 42.09% |
| Mar 31, 2013 | 41.01% |
| Dec 31, 2012 | 27.18% |
| Sep 30, 2012 | 38.25% |
| Jul 1, 2012 | 43.98% |
| Apr 1, 2012 | 37.04% |
| Dec 31, 2011 | 28.05% |
| Oct 2, 2011 | 32.98% |
| Jul 3, 2011 | 34.48% |
| Apr 3, 2011 | 32.24% |
| Dec 31, 2010 | 8.16% |
| Oct 3, 2010 | 30.75% |
| Jul 4, 2010 | 32.73% |
| Apr 4, 2010 | 34.54% |
| Dec 31, 2009 | 0.06% |
| Sep 27, 2009 | 40.66% |
| Jun 28, 2009 | 36.50% |
| Mar 29, 2009 | 39.79% |