Astrazeneca (AZN) Operating Margin (2009 - 2026)
Astrazeneca's Operating Margin was 29.12% in Q3 2026, up 4.18 percentage points from 24.94% a year earlier and up 8.55 percentage points from the prior quarter.
Astrazeneca (AZN) Operating Margin (2009 - 2026) Analysis & Trends
On a trailing twelve-month basis, Astrazeneca's Operating Margin was 24.88% through Sep 30, 2026, up 1.64 percentage points year-over-year; for FY2025, it came in at 23.40%, up 4.90 percentage points from FY2024.
- Operating Margin has now increased for four consecutive years, with a five-year change of +4.00 percentage points (FY2020 to FY2025).
- In earlier years, Operating Margin was 18.50% in FY2024 (+0.61 pp), 17.88% in FY2023 (+9.41 pp), 8.47% in FY2022 (+5.65 pp) and 2.82% in FY2021 (-16.57 pp).
- Quarterly Operating Margin has moved between -2.54% (Q4 2021) and 29.51% (Q1 2026) over five years.
- Compared with a year earlier, Operating Margin was higher in seven of the last eight quarters, with an average year-over-year change of +3.21 percentage points.
- The best year-over-year quarter for Operating Margin over five years was Q3 2022 (a gain of 28.52 percentage points); the worst was Q4 2021 (a drop of 23.75 percentage points).
- Per Business Quant data, AZN's Operating Margin in the three quarters before Q3 2026 was 20.57% (Q2 2026), 29.51% (Q1 2026) and 20.48% (Q4 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,359.75 Bn | 1,333.37 Bn | 20.46 Bn | 34.46% |
| 2 | Johnson & Johnson | 688.76 Bn | 608.62 Bn | 17.30 Bn | 24.35% |
| 3 | AbbVie | 521.69 Bn | 489.75 Bn | 13.12 Bn | 36.01% |
| 4 | Merck | 364.31 Bn | 327.31 Bn | 13.19 Bn | 30.74% |
| 5 | Novartis Ag | 306.35 Bn | 279.93 Bn | - | - |
| 6 | Astrazeneca | 285.96 Bn | 259.56 Bn | 13.26 Bn | 29.12% |
| 7 | Amgen | 251.88 Bn | 203.53 Bn | 7.58 Bn | 35.79% |
| 8 | Gilead Sciences | 208.59 Bn | 183.61 Bn | 6.73 Bn | 41.71% |
| 9 | Pfizer | 164.73 Bn | 112.38 Bn | 12.56 Bn | 32.98% |
| 10 | Vertex Pharmaceuticals | 136.55 Bn | 104.28 Bn | 2.91 Bn | 20.72% |
Historic Data
| Date | Value |
|---|---|
| Sep 30, 2026 | 29.12% |
| Jun 30, 2026 | 20.57% |
| Mar 31, 2026 | 29.51% |
| Dec 31, 2025 | 20.48% |
| Sep 30, 2025 | 24.94% |
| Jun 30, 2025 | 24.27% |
| Mar 31, 2025 | 28.54% |
| Dec 31, 2024 | 15.24% |
| Sep 30, 2024 | 16.27% |
| Jun 30, 2024 | 21.22% |
| Mar 31, 2024 | 25.58% |
| Dec 31, 2023 | 10.90% |
| Sep 30, 2023 | 17.73% |
| Jun 30, 2023 | 21.51% |
| Mar 31, 2023 | 24.12% |
| Dec 31, 2022 | 9.47% |
| Sep 30, 2022 | 11.34% |
| Jun 30, 2022 | 5.00% |
| Mar 31, 2022 | 7.71% |
| Dec 31, 2021 | -2.54% |
Astrazeneca Operating Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=operating-margin&ticker=AZN&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "operating-margin", "ticker": "AZN", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=operating-margin&ticker=AZN&period=max&api_key=YOUR_API_KEY");
const data = await res.json();