KPIs & Operating Metrics(New)
Growth Metrics

Amgen (AMGN) Operating Margin (2016 - 2025)

Amgen has reported Operating Margin over the past 17 years, most recently at 27.57% for Q4 2025.

  • Quarterly results put Operating Margin at 27.57% for Q4 2025, up 213.0% from a year ago — trailing twelve months through Dec 2025 was 24.71% (up 299.0% YoY), and the annual figure for FY2025 was 24.71%, up 299.0%.
  • Operating Margin for Q4 2025 was 27.57% at Amgen, up from 26.43% in the prior quarter.
  • Over the last five years, Operating Margin for AMGN hit a ceiling of 485.84% in Q4 2022 and a floor of 12.69% in Q2 2021.
  • Median Operating Margin over the past 5 years was 29.11% (2023), compared with a mean of 50.72%.
  • Biggest five-year swings in Operating Margin: skyrocketed 45218bps in 2022 and later plummeted -47033bps in 2023.
  • Amgen's Operating Margin stood at 33.65% in 2021, then soared by 1344bps to 485.84% in 2022, then tumbled by -97bps to 15.51% in 2023, then soared by 64bps to 25.43% in 2024, then increased by 8bps to 27.57% in 2025.
  • The last three reported values for Operating Margin were 27.57% (Q4 2025), 26.43% (Q3 2025), and 28.94% (Q2 2025) per Business Quant data.