Growth Metrics

Eli Lilly (LLY) Operating Margin (2016 - 2025)

Eli Lilly (LLY) has disclosed Operating Margin for 17 consecutive years, with 46.15% as the latest value for Q4 2025.

  • For the quarter ending Q4 2025, Operating Margin rose 671.0% year-over-year to 46.15%, compared with a TTM value of 44.82% through Dec 2025, up 890.0%, and an annual FY2025 reading of 44.82%, up 890.0% over the prior year.
  • Operating Margin was 46.15% for Q4 2025 at Eli Lilly, up from 45.57% in the prior quarter.
  • Across five years, Operating Margin topped out at 46.15% in Q4 2025 and bottomed at 21.19% in Q2 2021.
  • Average Operating Margin over 5 years is 32.63%, with a median of 31.29% recorded in 2021.
  • The sharpest move saw Operating Margin crashed -993bps in 2023, then skyrocketed 1150bps in 2025.
  • Year by year, Operating Margin stood at 29.86% in 2021, then dropped by -5bps to 28.44% in 2022, then rose by 13bps to 32.18% in 2023, then rose by 23bps to 39.44% in 2024, then increased by 17bps to 46.15% in 2025.
  • Business Quant data shows Operating Margin for LLY at 46.15% in Q4 2025, 45.57% in Q3 2025, and 45.13% in Q2 2025.