Eli Lilly (LLY) Operating Margin (2009 - 2026)

Eli Lilly (LLY) reported Operating Margin of 47.98% for Q1 2026, up 660.0% on a YoY basis from 6.31% in Q1 2025, and up 3.96% quarter-over-quarter from 46.15% in Q4 2025.

Eli Lilly (LLY) Operating Margin (2009 - 2026) Analysis & Trends

Eli Lilly has reported Operating Margin for 18 years, with the latest figure at 47.98% in Q1 2026.

  • For the quarter ending Q1 2026, Operating Margin rose 660.0% year-over-year to 47.98%; the trailing twelve-month figure through Mar 2026 stood at 46.29% (up 787.0% YoY), and the FY2025 full-year result was 44.82%, up 890.0% from the prior year.
  • Operating Margin for Q1 2026 stood at 47.98%, up from 46.15% in the prior quarter.
  • The five-year high for Operating Margin was 47.98% in Q1 2026, with the low at 22.97% in Q1 2023.
  • Historically, Operating Margin has averaged 35.15% across 5 years, with a median of 34.23% in 2024.
  • Annual changes were most pronounced in 2023 — Operating Margin sank 993 bps — and 2025, when it soared 1150 bps.
  • Eli Lilly's Operating Margin stood at 28.44% in 2022, then gained by 13 bps to 32.18% in 2023, then gained by 23 bps to 39.44% in 2024, then climbed by 17 bps to 46.15% in 2025, then rose by 4 bps to 47.98% in 2026.
  • The last three Operating Margin figures came in at 47.98% (Q1 2026), 46.15% (Q4 2025), and 45.57% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Operating Margin (Qtr)
1 Gsk 93,699,046.73 Bn 93,699,041.77 Bn 7.76 Bn 30.06%
2 Eli Lilly 1,012.06 Bn 1,006.77 Bn 16.22 Bn 47.98%
3 Johnson & Johnson 560.67 Bn 538.62 Bn 15.96 Bn 26.44%
4 AbbVie 402.20 Bn 392.85 Bn 10.78 Bn 26.60%
5 Merck 298.59 Bn 292.94 Bn 12.09 Bn -47.46%
6 Amgen 188.77 Bn 176.74 Bn 5.87 Bn 30.94%
7 Gilead Sciences 160.22 Bn 152.49 Bn 5.52 Bn 37.16%
8 Pfizer 148.19 Bn 135.42 Bn -1.21 Bn -286.83%
9 Bristol Myers Squibb 116.72 Bn 106.26 Bn 8.07 Bn -1.58%
10 Novartis Ag 109.78 Bn 109.09 Bn - -

Historic Data

Download Data
DateValue
Mar 31, 2026 47.98%
Dec 31, 2025 46.15%
Sep 30, 2025 45.57%
Jun 30, 2025 45.13%
Mar 31, 2025 41.38%
Dec 31, 2024 39.44%
Sep 30, 2024 38.05%
Jun 30, 2024 34.23%
Mar 31, 2024 29.88%
Dec 31, 2023 32.18%
Sep 30, 2023 36.06%
Jun 30, 2023 26.74%
Mar 31, 2023 22.97%
Dec 31, 2022 28.44%
Sep 30, 2022 25.05%
Jun 30, 2022 25.44%
Mar 31, 2022 32.91%
Dec 31, 2021 29.44%
Sep 30, 2021 30.40%
Jun 30, 2021 21.46%