Pyxis Oncology PYXS Insider Ownership

NASDAQ PYXS

$1.80 -0.04 (-1.90%)

As of: Oct 21, 2026 · 11:40 AM EDT

Insider Holdings by Owner

28.78Mn Shares

Insider Ownership Statistics

as of 30 Sep, 2026

Insider Ownership

11.89%

■0% pp QoQ

Shares Held by Insiders

7.61Mn

filed for Sep 2026

■0.00% QoQ

Shares Outstanding

63.99Mn

63,991,609 shares

Direct Holdings

5.28Mn

Indirect: 2.33Mn

Net Shares Traded (QoQ)

no net change in Sep 2026

Insiders Holding Shares

with Form 4 holdings on file

Shares Owned by Insiders

Shares held % of outstanding

Latest —

Average ownership —

Peak ownership —

Shares Purchased/Sold by Insiders

Bought Sold

Latest quarter —

Net over range —

Buying quarters —

Insider Ownership Summary

Updated Oct 10, 2026

Over the past year, PYXS insiders bought 5.52Mn shares on the open market with no usable reported price, and sold $107,100 of stock on the open market (35K shares).

Jakob Dupont (Director) was the top open-market seller of Pyxis Oncology over the past 12 months, with $107,100 sold (35K shares) and the latest sale on June 30, 2026.
Gordonmd Global Investments LP (10% owner) made the most recent open-market trade by an insider of Pyxis Oncology, a purchase of 5.52Mn shares on October 1, 2026.
Apart from open-market trades, PYXS insiders received 109.46K shares in stock awards and acquired 35K shares through option exercises and conversions in the past 12 months.
Business Quant data shows Pyxis Oncology insiders holding 23.15Mn shares in total in their latest Form 4 filings.
By type of ownership, PYXS insiders hold 22.81% of their shares directly (5.28Mn shares) and 77.19% indirectly (17.87Mn shares).
Business Quant counts 11 insiders with holdings in Pyxis Oncology stock, among the officers, directors and 10% owners who have filed a Form 4 in the past two years.
PYXS's largest insider holders by reported holdings are Gordonmd Global Investments LP (10% owner, 15.54Mn shares), Pamela Ann Connealy (CFO & COO, 3.43Mn shares) and Lara Sullivan (President, CEO & CMO, 2.4Mn shares).
Of the shares held by PYXS insiders, 67.13% belong to Gordonmd Global Investments LP.
Institutional investors held 53.38% of Pyxis Oncology stock at the end of Q2 2026, while the latest Form 4 filings of its insiders account for about 36.18%; other investors, including the public, hold roughly 10.44%.
Over the past 12 months, 10 insiders reported transactions in Pyxis Oncology stock in 15 Form 4 filings.
The insider holdings and trades above for Pyxis Oncology reflect Form 4 filings through October 9, 2026.

Form 4 Holdings

Insiders Holding PYXS

Insiders 14

Shares held 28.78Mn

Of outstanding 44.97%

#	Insider	Position	Direct	Indirect	Total	Share of Insiders	Last Filed
1	Global Investments Lp Gordonmd	TenPercentOwner	0	15,541,909	15,541,909	54.0%	02 Oct, 2026
2	Inc Pfizer	TenPercentOwner	5,952,263	0	5,952,263	20.7%	23 Mar, 2023
3	Lara Sullivan	President And Ceo	2,403,882	0	2,403,882	8.4%	18 Sep, 2023
4	Pamela Ann Connealy	Cfo Coo	0	2,314,886	2,314,886	8.0%	27 Nov, 2024
5	Jay Feingold	Chief Medical Officer	730,345	0	730,345	2.5%	28 Mar, 2023
6	Jitendra Wadhane	Prin Fin Acct Officer	512,882	0	512,882	1.8%	25 Mar, 2026
7	John L Flavin	Director	413,015	0	413,015	1.4%	28 Mar, 2024
8	Darren S Cline	Director	251,405	0	251,405	0.9%	28 Mar, 2024
9	Freda C Lewis-Hall	Director	241,405	0	241,405	0.8%	28 Mar, 2024
10	Thomas Civik	Director	206,186	0	206,186	0.7%	28 Mar, 2023
11	Rachel Humphrey	Director	96,805	0	96,805	0.3%	28 Mar, 2024
12	Mark Chin	Director	66,831	0	66,831	0.2%	04 Apr, 2022
13	Jakob Dupont	Director	38,741	0	38,741	0.1%	02 Jul, 2026
14	Santhosh Palani	Director	6,000	0	6,000	0.0%	07 Jun, 2024

Each row is that insider’s most recently reported position, from Form 4 filings over the last 60 months — which is why this total does not tie to the quarterly series above, where a quarter counts only the insiders who filed in it. Shares held through a fund or institutional portfolio are counted on the institutional ownership page instead.

Form 4 Filings

137 Insider Transactions

Source SEC Form 4

Latest quarter Sep 2026

Date	Insider	Position	Transaction	Shares	Price	Value	Shares Held After	Ownership
01 Oct, 2026	Global Investments Lp Gordonmd	TenPercentOwner	Acquired P	7,172,000	—	—	7,172,000	Indirect
01 Oct, 2026	Global Investments Lp Gordonmd	TenPercentOwner	Acquired P	5,517,000	—	—	15,541,909	Indirect
01 Oct, 2026	Global Investments Lp Gordonmd	TenPercentOwner	Acquired P	7,546,766	—	—	7,546,766	Indirect
04 Sep, 2026	Thomas Civik	Ceo Chairman Of The Board	Acquired A	2,503,050	$0.00	$0	2,503,050	Direct
20 Aug, 2026	Jakob Dupont	Director	Acquired A	46,000	$0.00	$0	46,000	Direct
12 Aug, 2026	Thomas Civik	Interim Ceo	Acquired A	250,956	$0.00	$0	941,087	Direct
30 Jun, 2026	Jakob Dupont	Director	Acquired M	35,000	$1.60	$56.00K	73,741	Direct
30 Jun, 2026	Jakob Dupont	Director	Disposed S	35,000	$3.06	$107.10K	38,741	Direct
30 Jun, 2026	Jakob Dupont	Director	Disposed M	35,000	$0.00	$0	357,461	Direct
24 Mar, 2026	Rachel Humphrey	Director	Acquired A	45,867	$0.00	$0	45,867	Direct
24 Mar, 2026	Jakob Dupont	Director	Acquired A	45,867	$0.00	$0	45,867	Direct
24 Mar, 2026	Michael A Metzger	Director	Acquired A	45,867	$0.00	$0	45,867	Direct
24 Mar, 2026	Freda C Lewis-Hall	Director	Acquired A	45,867	$0.00	$0	45,867	Direct
24 Mar, 2026	Darren S Cline	Director	Acquired A	45,867	$0.00	$0	45,867	Direct
24 Mar, 2026	Jitendra Wadhane	Prin Fin Acct Officer	Acquired A	109,461	$0.00	$0	512,882	Direct
24 Mar, 2026	John L Flavin	Director	Acquired A	45,867	$0.00	$0	45,867	Direct
24 Mar, 2026	Santhosh Palani	Director	Acquired A	45,867	$0.00	$0	45,867	Direct
24 Mar, 2026	Jitendra Wadhane	Prin Fin Acct Officer	Acquired A	262,635	$0.00	$0	262,635	Direct
03 Feb, 2026	Thomas Civik	Interim Ceo	Acquired A	690,131	$0.00	$0	690,131	Direct
31 Mar, 2025	John L Flavin	Director	Acquired A	36,979	$0.98	$36.24K	36,979	Direct

Showing 1 to 20 of 137 transactions