Pyxis Oncology PYXS Institutional Ownership

NASDAQ PYXS

$1.76 -0.08 (-4.35%)

At close: Oct 21, 2026 · 4:00 PM EDT

Institutions by Trading Activity

76 Institutions

Increased 35 46.1%

Unchanged 17 22.4%

Reduced 24 31.6%

Ownership Statistics

13F · as of 30 Jun, 2026

Institutional Ownership

53.38%

▲+9.50 pp QoQ

Shares Held by Institutions

34.16Mn

of 63.99Mn outstanding

▲+23.91% QoQ

Shares Outstanding

63.99Mn

29.83Mn held outside 13F filers

Institutional Investors

filed 13F for Jun 2026

▼-1 vs prior quarter

Net Shares Added (QoQ)

+6.59Mn

accumulated since last quarter

Value of Holdings

$62.86Mn

reported market value

Shares Owned by Institutions

Shares held % of outstanding

Latest —

Average ownership —

Peak ownership —

Shares Purchased/Sold by Institutions

Accumulated Distributed

Latest quarter —

Net over range —

Accumulating quarters —

Ownership Summary

Updated Oct 11, 2026

Pyxis Oncology, Inc. (NASDAQ:PYXS) counted 76 institutional investors among its 13F-reported shareholders for the quarter ended June 30, 2026.

These investors held 53.38% of outstanding shares in Q2 2026, up from 43.88% the quarter before.
Total shares held in PYXS rose 23.91% from Q1 2026; the number of holders rose 4.11% from Q2 2025.
Among the 76 holders of Pyxis Oncology, 35 added to their positions, 24 reduced their stakes and 17 left their positions unchanged.
Altogether, institutional holders owned 34.16Mn PYXS shares at the end of Q2 2026, up 6.59Mn from the prior quarter and up 6.83Mn from a year earlier.
GordonMD Global Investments LP held the largest position in PYXS at 10.02Mn shares as of June 30, 2026, or 15.67% of shares outstanding.
Among holders that already owned Pyxis Oncology, the biggest buyers in Q2 2026 were GordonMD Global Investments LP (+5.9Mn shares), Atle Fund Management AB (+769.42K shares), Marshall Wace, LLP (+476.13K shares), BlackRock, Inc. (+79.09K shares) and Bank of America Corp (+63.66K shares).
Holders that trimmed the most shares of Pyxis Oncology in Q2 2026 while keeping a position were 683 Capital Management, LLC (-436.9K shares), Millennium Management LLC (-164.62K shares), Longaeva Partners L.P. (-149.63K shares), Palo Alto Investors LP (-146.23K shares) and Renaissance Technologies LLC (-116.45K shares).
According to Business Quant data, the leading holders of PYXS for Q2 2026 were GordonMD Global Investments LP (10.02Mn shares), Pfizer Inc (7.03Mn shares), Laurion Capital Management LP (4.9Mn shares), Vanguard Capital Management LLC (2.08Mn shares), Atle Fund Management AB (966.46K shares), BlackRock, Inc. (867.93K shares), Palo Alto Investors LP (864.28K shares), Marshall Wace, LLP (830.54K shares), Renaissance Technologies LLC (772.23K shares) and Geode Capital Management, LLC (591.85K shares).

Form 13F Holdings

76 Institutional Holders

Report period 30 Jun, 2026

Total shares held 34.16Mn

Of outstanding 53.38%

#	Institution	CIK	Shares Held	% of Outstanding	Change (QoQ)	Change (%)	Value (USD)
1	GordonMD Global Investments LP	0002039349	10,024,909	15.67%	▲5,903,039	+143.21%	$30.17Mn
2	Pfizer Inc	0000078003	7,032,770	10.99%	0	0.00%	$19.48Mn
3	Laurion Capital Management LP	0001390202	4,900,888	7.66%	▼96,445	-1.93%	$14.75Mn
4	VANGUARD CAPITAL MANAGEMENT LLC	0002100119	2,075,997	3.24%	▲42,487	+2.09%	$6.25Mn
5	Atle Fund Management AB	0001381843	966,459	1.51%	▲769,423	+390.50%	$2.91Mn
6	BlackRock, Inc.	0002012383	867,934	1.36%	▲79,095	+10.03%	$2.61Mn
7	Palo Alto Investors LP	0001306923	864,277	1.35%	▼146,233	-14.47%	$2.60Mn
8	MARSHALL WACE, LLP	0001318757	830,544	1.30%	▲476,127	+134.34%	$2.50Mn
9	RENAISSANCE TECHNOLOGIES LLC	0001037389	772,232	1.21%	▼116,448	-13.10%	$2.32Mn
10	GEODE CAPITAL MANAGEMENT, LLC	0001214717	591,849	0.92%	▼6,272	-1.05%	$1.78Mn
11	Woodline Partners LP	0001784547	523,999	0.82%	▲523,999	0.00%	$1.58Mn
12	683 Capital Management, LLC	0001404574	459,367	0.72%	▼436,896	-48.75%	$1.38Mn
13	JACOBS LEVY EQUITY MANAGEMENT, INC	0000884414	428,606	0.67%	▼32,391	-7.03%	$1.29Mn
14	Longaeva Partners L.P.	0002054122	353,582	0.55%	▼149,632	-29.74%	$1.06Mn
15	Decheng Capital LLC	0002010850	326,810	0.51%	0	0.00%	$983.70K
16	VANGUARD FIDUCIARY TRUST CO	0000933478	302,986	0.47%	▲2,089	+0.69%	$911.99K
17	JANE STREET GROUP, LLC	0001595888	290,090	0.45%	▼14,369	-4.72%	$873.17K
18	State Street Corp	0000093751	248,837	0.39%	0	0.00%	$749.00K
19	MILLENNIUM MANAGEMENT LLC	0001273087	233,004	0.36%	▼164,621	-41.40%	$701.34K
20	UBS Group AG	0001610520	155,217	0.24%	▼98,907	-38.92%	$467.20K

Showing 1 to 20 of 76 holders