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Vertex Pharmaceuticals (VRTX) Operating Margin (2016 - 2025)

Historic Operating Margin for Vertex Pharmaceuticals (VRTX) over the last 17 years, with Q4 2025 value amounting to 37.8%.

  • Vertex Pharmaceuticals' Operating Margin rose 25700.0% to 37.8% in Q4 2025 from the same period last year, while for Dec 2025 it was 34.77%, marking a year-over-year increase of 368900.0%. This contributed to the annual value of 34.77% for FY2025, which is 368900.0% up from last year.
  • Latest data reveals that Vertex Pharmaceuticals reported Operating Margin of 37.8% as of Q4 2025, which was up 25700.0% from 38.56% recorded in Q3 2025.
  • In the past 5 years, Vertex Pharmaceuticals' Operating Margin registered a high of 53.15% during Q3 2021, and its lowest value of 132.85% during Q2 2024.
  • Moreover, its 5-year median value for Operating Margin was 40.72% (2024), whereas its average is 30.8%.
  • Per our database at Business Quant, Vertex Pharmaceuticals' Operating Margin crashed by -1740200bps in 2024 and then soared by 1716800bps in 2025.
  • Over the past 5 years, Vertex Pharmaceuticals' Operating Margin (Quarter) stood at 42.35% in 2021, then rose by 6bps to 44.88% in 2022, then decreased by -13bps to 39.26% in 2023, then dropped by -10bps to 35.23% in 2024, then increased by 7bps to 37.8% in 2025.
  • Its Operating Margin was 37.8% in Q4 2025, compared to 38.56% in Q3 2025 and 38.83% in Q2 2025.