Vertex Pharmaceuticals (VRTX) Operating Margin (2009 - 2026)
Vertex Pharmaceuticals (VRTX) posted Operating Margin of 37.4% for Q2 2026, down 1.84% on a QoQ basis from 38.1% in Q1 2026, and down 143.0% year-over-year from 86.98% in Q2 2025.
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Vertex Pharmaceuticals (VRTX) Operating Margin (2009 - 2026) Analysis & Trends
Vertex Pharmaceuticals has reported Operating Margin for 18 years, with the latest figure at 37.4% in Q2 2026.
- On a quarterly basis, Operating Margin fell 143.0% year-over-year to 37.4% in Q2 2026; TTM through Jun 2026 was 37.95%, a 359.0% increase from a year earlier, with the FY2025 full-year figure at 34.77%, up 3689.0% from the prior year.
- Operating Margin was 37.4% for Q2 2026 at Vertex Pharmaceuticals, down from 38.1% in the prior quarter.
- The five-year high for Operating Margin was 50.37% in Q2 2022, with the low at 132.85% in Q2 2024.
- Average Operating Margin over 5 years is 30.37%, with a median of 39.04% recorded in 2023.
- The sharpest annual moves came in 2024 and 2025: Operating Margin sank 17402 bps in 2024, then surged 17168 bps in 2025.
- Over 5 years, Operating Margin stood at 44.88% in 2022, then dropped by 13 bps to 39.26% in 2023, then dropped by 10 bps to 35.23% in 2024, then advanced by 7 bps to 37.8% in 2025, then slipped by 1 bps to 37.4% in 2026.
- The last three Operating Margin figures came in at 37.4% (Q2 2026), 38.1% (Q1 2026), and 37.8% (Q4 2025), per Business Quant data.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 649.01 Bn | 628.25 Bn | 17.26 Bn | 28.21% |
| 2 | AbbVie | 468.55 Bn | 462.03 Bn | 12.70 Bn | 37.86% |
| 3 | Merck | 365.49 Bn | 358.40 Bn | 12.21 Bn | -3.52% |
| 4 | Novartis Ag | 272.39 Bn | 265.10 Bn | 11.24 Bn | 32.97% |
| 5 | Astrazeneca | 253.18 Bn | 247.96 Bn | 12.86 Bn | 20.57% |
| 6 | Amgen | 219.53 Bn | 205.54 Bn | 7.24 Bn | 34.95% |
| 7 | Gilead Sciences | 187.85 Bn | 184.59 Bn | 6.22 Bn | -133.21% |
| 8 | Pfizer | 160.56 Bn | 149.16 Bn | 10.94 Bn | 28.37% |
| 9 | Vertex Pharmaceuticals | 130.81 Bn | 122.96 Bn | 2.84 Bn | 37.40% |
| 10 | Bristol Myers Squibb | 124.95 Bn | 113.89 Bn | 9.25 Bn | 2.77% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 37.40% |
| Mar 31, 2026 | 38.10% |
| Dec 31, 2025 | 37.80% |
| Sep 30, 2025 | 38.56% |
| Jun 30, 2025 | 38.83% |
| Mar 31, 2025 | 22.75% |
| Dec 31, 2024 | 35.23% |
| Sep 30, 2024 | 40.27% |
| Jun 30, 2024 | -132.85% |
| Mar 31, 2024 | 42.35% |
| Dec 31, 2023 | 39.26% |
| Sep 30, 2023 | 41.80% |
| Jun 30, 2023 | 41.17% |
| Mar 31, 2023 | 32.80% |
| Dec 31, 2022 | 44.88% |
| Sep 30, 2022 | 48.27% |
| Jun 30, 2022 | 50.37% |
| Mar 31, 2022 | 49.63% |
| Dec 31, 2021 | 42.35% |
| Sep 30, 2021 | 53.15% |
API Access
Vertex Pharmaceuticals Operating Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=operating-margin&ticker=VRTX&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "operating-margin", "ticker": "VRTX", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=operating-margin&ticker=VRTX&period=max&api_key=YOUR_API_KEY");
const data = await res.json();