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Vertex Pharmaceuticals (VRTX) Operating Margin: 2009-2025

Historic Operating Margin for Vertex Pharmaceuticals (VRTX) over the last 17 years, with Sep 2025 value amounting to 38.56%.

  • Vertex Pharmaceuticals' Operating Margin fell 171.00% to 38.56% in Q3 2025 from the same period last year, while for Sep 2025 it was 34.06%, marking a year-over-year increase of 3661.00%. This contributed to the annual value of -2.11% for FY2024, which is 4094.00% down from last year.
  • As of Q3 2025, Vertex Pharmaceuticals' Operating Margin stood at 38.56%, which was down 0.69% from 38.83% recorded in Q2 2025.
  • In the past 5 years, Vertex Pharmaceuticals' Operating Margin registered a high of 53.15% during Q3 2021, and its lowest value of -132.85% during Q2 2024.
  • Moreover, its 3-year median value for Operating Margin was 38.83% (2025), whereas its average is 21.83%.
  • In the last 5 years, Vertex Pharmaceuticals' Operating Margin plummeted by 17,402bps in 2024 and then skyrocketed by 17,168bps in 2025.
  • Over the past 5 years, Vertex Pharmaceuticals' Operating Margin (Quarterly) stood at 42.35% in 2021, then soared by 253bps to 44.88% in 2022, then slumped by 562bps to 39.26% in 2023, then slumped by 403bps to 35.23% in 2024, then plummeted by 171bps to 38.56% in 2025.
  • Its last three reported values are 38.56% in Q3 2025, 38.83% for Q2 2025, and 22.75% during Q1 2025.