Lexicon Pharmaceuticals (LXRX) Operating Margin (2010 - 2026)
Lexicon Pharmaceuticals (LXRX) reported Operating Margin of 4.72% for Q1 2026, up 203007.0% year-over-year from N/an in Q1 2025, and up 98.25% quarter-over-quarter from 269.07% in Q4 2025.
Lexicon Pharmaceuticals (LXRX) Operating Margin (2010 - 2026) Analysis & Trends
Lexicon Pharmaceuticals (LXRX) has 16 years of Operating Margin data on file, last reported at 4.72% in Q1 2026.
- Operating Margin for Q1 2026 came in at 4.72%, up 203007.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 34.79% (up 53377.0% YoY), and the FY2025 annual result was 98.21%, up 53600.0% from the prior year.
- Operating Margin climbed to 4.72% in Q1 2026 per LXRX's latest filing, from 269.07% in the prior quarter.
- Over five years, Operating Margin peaked at 12.94% in Q2 2025 and troughed at 30636.42% in Q3 2023.
- A 4-year average of 5362.22% and a median of 2697.84% in 2024 frame the typical range for Operating Margin.
- The sharpest annual moves came in 2024 and 2025: Operating Margin surged 2699682 bps in 2024, then plunged 14579 bps in 2025.
- A 4-year view of Operating Margin shows it stood at 6101.44% in 2023, then soared by 98 bps to 123.28% in 2024, then sank by 118 bps to 269.07% in 2025, then surged by 98 bps to 4.72% in 2026.
- Business Quant data shows LXRX's Operating Margin at 4.72% in Q1 2026, 269.07% in Q4 2025, and 85.93% in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | - |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -6.43% |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | - |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 38.10% |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | - |
| 10 | Lexicon Pharmaceuticals | 804.48 Mn | 633.82 Mn | 20.99 Mn | -4.72% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -4.72% |
| Dec 31, 2025 | -269.07% |
| Sep 30, 2025 | -85.93% |
| Jun 30, 2025 | 12.94% |
| Mar 31, 2025 | -2,034.79% |
| Dec 31, 2024 | -123.28% |
| Sep 30, 2024 | -3,639.60% |
| Jun 30, 2024 | -3,360.90% |
| Mar 31, 2024 | -4,147.58% |
| Dec 31, 2023 | -6,101.44% |
| Sep 30, 2023 | -30,636.42% |
| Jun 30, 2023 | -13,955.84% |
| Dec 31, 2021 | 8,919.01% |
| Jun 30, 2021 | -7,674.79% |
| Mar 31, 2021 | -77,181.48% |
| Dec 31, 2020 | 31.38% |
| Jun 30, 2020 | -258,316.00% |
| Mar 31, 2020 | -780.57% |
| Dec 31, 2019 | -541.05% |
| Sep 30, 2019 | 76.30% |