Lexicon Pharmaceuticals (LXRX) Operating Margin (2010 - 2026)

Lexicon Pharmaceuticals' (LXRX) quarterly Operating Margin came in at 4.72% in Q1 2026, up 203007.0% year-on-year from N/an in Q1 2025, and up 98.25% on a QoQ basis from 269.07% in Q4 2025.

Lexicon Pharmaceuticals (LXRX) Operating Margin (2010 - 2026) Analysis & Trends

Lexicon Pharmaceuticals (LXRX) has 16 years of Operating Margin data on file, last reported at 4.72% in Q1 2026.

  • On a quarterly basis, Operating Margin rose 203007.0% year-over-year to 4.72% in Q1 2026; TTM through Mar 2026 was 34.79%, a 53377.0% increase from a year earlier, with the FY2025 full-year figure at 98.21%, up 53600.0% from the prior year.
  • Operating Margin for Q1 2026 stood at 4.72%, up from 269.07% in the prior quarter.
  • Over the last five years, Operating Margin for LXRX reached as high as 12.94% in Q2 2025 and fell as low as 68591.43% in Q2 2022.
  • Historically, Operating Margin has averaged 10321.92% across 5 years, with a median of 3360.9% in 2024.
  • Across the five-year window, Operating Margin surged 5338868 bps in 2023 and slumped 14579 bps in 2025, its largest moves.
  • Year by year, Operating Margin stood at 68591.43% in 2022, then jumped by 91 bps to 6101.44% in 2023, then soared by 98 bps to 123.28% in 2024, then slumped by 118 bps to 269.07% in 2025, then surged by 98 bps to 4.72% in 2026.
  • Per Business Quant data, the three most recent Operating Margin figures were 4.72% in Q1 2026, 269.07% in Q4 2025, and 85.93% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Operating Margin (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 16.51%
4 NuCana 279.75 Bn 279.75 Bn - -
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 38.10%
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 17.83%
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 31.68%
9 Revolution Medicines 37.78 Bn 37.78 Bn - -
10 Lexicon Pharmaceuticals 979.13 Mn 808.47 Mn 20.99 Mn -4.72%

Historic Data

Download Data
DateValue
Mar 31, 2026 -4.72%
Dec 31, 2025 -269.07%
Sep 30, 2025 -85.93%
Jun 30, 2025 12.94%
Mar 31, 2025 -2,034.79%
Dec 31, 2024 -123.28%
Sep 30, 2024 -3,639.60%
Jun 30, 2024 -3,360.90%
Mar 31, 2024 -4,147.58%
Dec 31, 2023 -6,101.44%
Sep 30, 2023 -30,636.42%
Jun 30, 2023 -15,202.75%
Jun 30, 2022 -68,591.43%
Dec 31, 2020 -3,747.74%
Jun 30, 2020 -258,316.00%
Mar 31, 2020 -780.57%
Dec 31, 2019 -541.05%
Sep 30, 2019 78.58%
Jun 30, 2019 -2,156.40%
Mar 31, 2019 -716.24%