Innoviva (INVA) Operating Margin (2011 - 2026)

Innoviva (INVA) posted Operating Margin of 38.94% for Q1 2026, up 103.06% on a QoQ basis from 1274.01% in Q4 2025, and down 781.0% year-over-year from 5.72% in Q1 2025.

Innoviva (INVA) Operating Margin (2011 - 2026) Analysis & Trends

Innoviva's Operating Margin history runs 16 years deep, the most recent figure standing at 38.94% for Q1 2026.

  • Quarterly Operating Margin fell 781.0% year-over-year to 38.94% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 39.88% (down 595.0% YoY) and the FY2025 annual result came in at 39.81%, down 671.0% from the prior year.
  • Operating Margin was 38.94% for Q1 2026 at Innoviva, up from 1274.01% in the prior quarter.
  • Across five years, Operating Margin topped out at 58.45% in Q3 2023 and bottomed at 1274.01% in Q4 2025.
  • A 5-year average of 434.34% and a median of 430.5% in 2023 frame the typical range for Operating Margin.
  • Annual changes were most pronounced in 2022 — Operating Margin slumped 411120 bps — and 2024, when it surged 116203 bps.
  • Innoviva's Operating Margin stood at 982.68% in 2022, then jumped by 56 bps to 430.5% in 2023, then plunged by 98 bps to 853.36% in 2024, then tumbled by 49 bps to 1274.01% in 2025, then surged by 103 bps to 38.94% in 2026.
  • Business Quant data shows INVA's Operating Margin at 38.94% in Q1 2026, 1274.01% in Q4 2025, and 42.05% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Operating Margin (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 16.51%
4 NuCana 279.75 Bn 279.75 Bn - -
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 38.10%
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 17.83%
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 31.68%
9 Revolution Medicines 37.78 Bn 37.78 Bn - -
10 Innoviva 1.57 Bn 969.11 Mn 75.83 Mn 38.94%

Historic Data

Download Data
DateValue
Mar 31, 2026 38.94%
Dec 31, 2025 -1,274.01%
Sep 30, 2025 42.05%
Jun 30, 2025 48.61%
Mar 31, 2025 46.74%
Dec 31, 2024 -853.36%
Sep 30, 2024 46.36%
Jun 30, 2024 54.74%
Mar 31, 2024 -673.86%
Dec 31, 2023 -430.50%
Sep 30, 2023 58.45%
Jun 30, 2023 -1,107.29%
Mar 31, 2023 -1,173.47%
Dec 31, 2022 -982.68%
Sep 30, 2022 27.00%
Jun 30, 2022 -585.27%
Mar 31, 2022 -666.20%
Dec 31, 2021 -611.53%
Sep 30, 2021 95.21%
Jun 30, 2021 3,525.93%