Xilio Therapeutics XLO
NASDAQ XLO
$8.99 +0.02 (+0.28%)
As of: Sep 10, 2026 · 1:21 PM EDT

Xilio Therapeutics (XLO) EV to FCF (2021 - 2026)

Xilio Therapeutics' (XLO) quarterly EV to FCF came in at 2.65 in Q2 2026, down 169.28% year-over-year from 3.83 in Q2 2025, and down 573.06% quarter-over-quarter from 0.56 in Q1 2026.

Analysis

Xilio Therapeutics (XLO) EV to FCF (2021 - 2026) Analysis & Trends

Xilio Therapeutics has disclosed EV to FCF across 6 years of filings, most recently posting 2.65 for Q2 2026.

  • In Q2 2026, EV to FCF fell 169.28% year-over-year to 2.65; the TTM figure through Jun 2026 stood at 0.81 (down 120.01% YoY), while the FY2025 annual figure was 11.36, up 1704.77% from the prior year.
  • EV to FCF came in at 2.65 for Q2 2026 at Xilio Therapeutics, down from 0.56 in the prior quarter.
  • In the past five years, EV to FCF ranged from a high of 29.91 in Q4 2025 to a low of 2.65 in Q2 2026.
  • Average EV to FCF over 5 years is 2.35, with a median of 0.46 recorded in 2024.
  • Year-over-year, EV to FCF slumped 616.98% in 2024 and soared 3554.36% in 2025.
  • Over 5 years, EV to FCF stood at 2.49 in 2022, then fell by 11.64% to 2.2 in 2023, then sank by 62.77% to 0.82 in 2024, then soared by 3554.36% to 29.91 in 2025, then sank by 108.87% to 2.65 in 2026.
  • Per Business Quant data, the three most recent EV to FCF figures were 2.65 in Q2 2026, 0.56 in Q1 2026, and 29.91 in Q4 2025.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr)
1 Amgen 206.44 Bn 192.45 Bn 7.24 Bn
2 Gilead Sciences 179.97 Bn 176.79 Bn 6.22 Bn
3 Vertex Pharmaceuticals 130.57 Bn 122.72 Bn 2.84 Bn
4 Regeneron Pharmaceuticals 81.63 Bn 73.63 Bn 3.93 Bn
5 Argenx Se 60.34 Bn 55.16 Bn 1.37 Bn
6 Moderna 54.37 Bn 49.23 Bn 52.00 Mn
7 Alnylam Pharmaceuticals 33.07 Bn 29.76 Bn 992.69 Mn
8 Biogen 31.84 Bn 30.55 Bn 1.96 Bn
9 Roivant Sciences 29.49 Bn 29.49 Bn 1.16 Mn
10 Xilio Therapeutics 174.55 Mn 38.51 Mn -
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 -2.65
Mar 31, 2026 0.56
Dec 31, 2025 29.91
Sep 30, 2025 -1.01
Jun 30, 2025 3.83
Mar 31, 2025 -1.22
Dec 31, 2024 0.82
Sep 30, 2024 0.82
Jun 30, 2024 -1.01
Mar 31, 2024 0.36
Dec 31, 2023 2.20
Sep 30, 2023 0.13
Jun 30, 2023 0.20
Mar 31, 2023 0.25
Dec 31, 2022 2.49
Sep 30, 2022 2.93
Jun 30, 2022 4.53
Mar 31, 2022 -0.79
Dec 31, 2021 6.18