Spruce Biosciences SPRB
NASDAQ SPRB
$51.99 -0.97 (-1.83%)
At close: Aug 20, 2026 · 4:00 PM EDT

Spruce Biosciences (SPRB) Operating Margin (2023 - 2024)

Spruce Biosciences (SPRB) posted quarterly Operating Margin of 3453.95% for Q4 2024, down 306898.0% year-over-year from N/an in Q1 2024, and down 120.28% quarter-over-quarter from 1568.0% in Q3 2024.

Spruce Biosciences (SPRB) Operating Margin (2023 - 2024) Analysis & Trends

Spruce Biosciences (SPRB) has reported Operating Margin for 2 consecutive years, with 3453.95% the latest figure, recorded in Q4 2024.

  • In Q4 2024, Operating Margin fell 306898.0% year-over-year to 3453.95%; the TTM figure through Sep 2025 stood at 7100.0% (down 649183.0% YoY), while the FY2024 annual figure was 1143.37%, down 62859.0% from the prior year.
  • Operating Margin retreated to 3453.95% in Q4 2024 per SPRB's latest filing, from 1568.0% in the prior quarter.
  • Across five years, Operating Margin topped out at 384.97% in Q4 2023 and bottomed at 3453.95% in Q4 2024.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Operating Margin (Qtr)
1 Vertex Pharmaceuticals 137.11 Bn 129.26 Bn 2.84 Bn 37.40%
2 Regeneron Pharmaceuticals 84.98 Bn 76.99 Bn 3.93 Bn 30.15%
3 Argenx Se 64.52 Bn 59.33 Bn 1.37 Bn 32.54%
4 Moderna 53.23 Bn 48.09 Bn 52.00 Mn -562.07%
5 BeOne Medicines 41.23 Bn 36.14 Bn 1.53 Bn 19.06%
6 Alnylam Pharmaceuticals 30.65 Bn 27.34 Bn 992.69 Mn 17.93%
7 Insmed 27.15 Bn 25.99 Bn 358.27 Mn -0.36%
8 Royalty Pharma 26.98 Bn 26.14 Bn - 19.75%
9 BioNTech SE 26.78 Bn 8.39 Bn 668.28 Mn -35.57%
10 Spruce Biosciences 127.07 Mn 127.07 Mn - -

Historic Data

Download Data
DateValue
Dec 31, 2024 -3,453.95%
Sep 30, 2024 -1,568.00%
Jun 30, 2024 -623.35%
Mar 31, 2024 -631.65%
Dec 31, 2023 -384.97%
Sep 30, 2023 -444.45%
Jun 30, 2023 -635.09%
Mar 31, 2023 -659.95%