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Asset Utilization RatioAssets AverageEBIT MarginEBITDA MarginEBT MarginEnterprise ValueEquity AverageEquity RatioFCF MarginInvested CapitalNet MarginOperating MarginReturn on AssetsReturn on Capital EmployedReturn on EquityReturn on Invested CapitalReturn on Sales

Septerna (SEPN) Operating Margin (2023 - 2026)

Septerna has reported Operating Margin over the past 4 years, most recently at 50.19% for Q1 2026.

  • For Q1 2026, Operating Margin rose 1178086.0% year-over-year to 50.19%; the TTM value through Mar 2026 reached 3.25%, up 934235.0%, while the annual FY2025 figure was 22.33%, 749609.0% up from the prior year.
  • Operating Margin for Q1 2026 was 50.19% at Septerna, down from 174.19% in the prior quarter.
  • Over five years, Operating Margin peaked at 29082.2% in Q4 2023 and troughed at 36484.85% in Q3 2023.
  • A 4-year average of 7062.69% and a median of 4886.44% in 2024 define the central range for Operating Margin.
  • On a YoY basis, Operating Margin climbed as much as 2367235bps in 2024 and fell as far as -4074164bps in 2024.
  • Year by year, Operating Margin stood at 29082.2% in 2023, then plummeted by -140bps to 11659.43% in 2024, then skyrocketed by 101bps to 174.19% in 2025, then tumbled by -129bps to 50.19% in 2026.
  • Business Quant data shows Operating Margin for SEPN at 50.19% in Q1 2026, 174.19% in Q4 2025, and 12.16% in Q3 2025.