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Septerna (SEPN) Operating Margin (2023 - 2025)

Historic Operating Margin for Septerna (SEPN) over the last 3 years, with Q3 2025 value amounting to 12.16%.

  • Septerna's Operating Margin rose 128246600.0% to 12.16% in Q3 2025 from the same period last year, while for Sep 2025 it was 349.25%, marking a year-over-year increase of 18717500.0%. This contributed to the annual value of 7518.42% for FY2024, which is 88925900.0% down from last year.
  • Per Septerna's latest filing, its Operating Margin stood at 12.16% for Q3 2025, which was up 128246600.0% from 24351.26% recorded in Q2 2025.
  • Septerna's Operating Margin's 5-year high stood at 29082.2% during Q4 2023, with a 5-year trough of 36484.85% in Q3 2023.
  • Over the past 3 years, Septerna's median Operating Margin value was 11659.43% (recorded in 2024), while the average stood at 8645.96%.
  • Within the past 5 years, the most significant YoY rise in Septerna's Operating Margin was 236723500bps (2024), while the steepest drop was -407416400bps (2024).
  • Over the past 3 years, Septerna's Operating Margin (Quarter) stood at 29082.2% in 2023, then plummeted by -140bps to 11659.43% in 2024, then soared by 100bps to 12.16% in 2025.
  • Its Operating Margin stands at 12.16% for Q3 2025, versus 24351.26% for Q2 2025 and 11831.05% for Q1 2025.