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Asset Utilization RatioAssets AverageEBIT MarginEBITDA MarginEBT MarginEnterprise ValueEquity AverageEquity RatioFCF MarginGross MarginInvested CapitalMarket CapitalizationNet MarginOperating MarginReturn on AssetsReturn on Capital EmployedReturn on EquityReturn on Invested CapitalReturn on Sales

Septerna (SEPN) Operating Margin: 2023-2025

Historic Operating Margin for Septerna (SEPN) over the last 2 years, with Sep 2025 value amounting to 12.16%.

  • Septerna's Operating Margin rose 1282466.00% to 12.16% in Q3 2025 from the same period last year, while for Sep 2025 it was -349.25%, marking a year-over-year increase of 187175.00%. This contributed to the annual value of -7,518.42% for FY2024, which is 889259.00% down from last year.
  • Latest data reveals that Septerna reported Operating Margin of 12.16% as of Q3 2025, which was up 100.05% from -24,351.26% recorded in Q2 2025.
  • Over the past 5 years, Septerna's Operating Margin peaked at 29,082.20% during Q4 2023, and registered a low of -36,484.85% during Q3 2023.
  • Its 3-year average for Operating Margin is -8,645.96%, with a median of -11,659.43% in 2024.
  • Data for Septerna's Operating Margin shows a peak YoY increase of 2,367,235bps (in 2024) and a maximum YoY decrease of 4,074,164bps (in 2024) over the last 5 years.
  • Septerna's Operating Margin (Quarterly) stood at 29,082.20% in 2023, then plummeted by 4,074,164bps to -11,659.43% in 2024, then spiked by 1,282,466bps to 12.16% in 2025.
  • Its Operating Margin stands at 12.16% for Q3 2025, versus -24,351.26% for Q2 2025 and -11,831.05% for Q1 2025.