Rhythm Pharmaceuticals (RYTM) Operating Margin (2021 - 2026)
Rhythm Pharmaceuticals' (RYTM) quarterly Operating Margin came in at 87.11% in Q1 2026, up 5662.0% year-on-year from 1.51% in Q1 2025, and down 5.97% on a QoQ basis from 82.2% in Q4 2025.
Rhythm Pharmaceuticals (RYTM) Operating Margin (2021 - 2026) Analysis & Trends
Rhythm Pharmaceuticals (RYTM) has 6 years of Operating Margin data on file, last reported at 87.11% in Q1 2026.
- On a quarterly basis, Operating Margin rose 5662.0% year-over-year to 87.11% in Q1 2026; TTM through Mar 2026 was 90.89%, a 3524.0% increase from a year earlier, with the FY2025 full-year figure at 101.19%, up 10284.0% from the prior year.
- Operating Margin for Q1 2026 stood at 87.11%, down from 82.2% in the prior quarter.
- Over the last five years, Operating Margin for RYTM reached as high as 523.15% in Q4 2022 and fell as low as 3517.42% in Q1 2022.
- Historically, Operating Margin has averaged 405.41% across 5 years, with a median of 143.73% in 2025.
- Across the five-year window, Operating Margin surged 9476258 bps in 2022 and sank 69343 bps in 2023, its largest moves.
- Year by year, Operating Margin stood at 523.15% in 2022, then tumbled by 133 bps to 170.28% in 2023, then soared by 42 bps to 98.63% in 2024, then climbed by 17 bps to 82.2% in 2025, then decreased by 6 bps to 87.11% in 2026.
- Per Business Quant data, the three most recent Operating Margin figures were 87.11% in Q1 2026, 82.2% in Q4 2025, and 102.64% in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | - |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | - |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | 16.51% |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | - |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | 38.10% |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | 17.83% |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | - |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | 31.68% |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | - |
| 10 | Rhythm Pharmaceuticals | 6.98 Bn | 6.64 Bn | 52.96 Mn | -87.11% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -87.11% |
| Dec 31, 2025 | -82.20% |
| Sep 30, 2025 | -102.64% |
| Jun 30, 2025 | -93.39% |
| Mar 31, 2025 | -143.73% |
| Dec 31, 2024 | -98.63% |
| Sep 30, 2024 | -131.98% |
| Jun 30, 2024 | -139.20% |
| Mar 31, 2024 | -538.71% |
| Dec 31, 2023 | -170.28% |
| Sep 30, 2023 | -195.31% |
| Jun 30, 2023 | -242.46% |
| Mar 31, 2023 | -458.03% |
| Dec 31, 2022 | 523.15% |
| Sep 30, 2022 | -916.60% |
| Jun 30, 2022 | -497.42% |
| Mar 31, 2022 | -3,517.42% |
| Dec 31, 2021 | -2,806.22% |
| Sep 30, 2021 | -4,303.50% |
| Jun 30, 2021 | -14,756.20% |