Rhythm Pharmaceuticals RYTM Insider Ownership

NASDAQ RYTM

$89.68 -0.52 (-0.58%)

As of: Oct 21, 2026 · 11:41 AM EDT

Insider Holdings by Owner

544.12K Shares

Insider Ownership Statistics

as of 30 Sep, 2026

Insider Ownership

0.789%

▼-0.063% pp QoQ

Shares Held by Insiders

543.25K

filed for Sep 2026

▼-7.41% QoQ

Shares Outstanding

68.82Mn

68,816,868 shares

Direct Holdings

529.08K

Indirect: 14.17K

Net Shares Traded (QoQ)

-43.48K

net selling in Sep 2026

Insiders Holding Shares

with Form 4 holdings on file

Shares Owned by Insiders

Shares held % of outstanding

Latest —

Average ownership —

Peak ownership —

Shares Purchased/Sold by Insiders

Bought Sold

Latest quarter —

Net over range —

Buying quarters —

Insider Ownership Summary

Updated Oct 10, 2026

Across the past 12 months, open-market trades by Rhythm Pharmaceuticals insiders were all sales, totaling $41.71 million (383.93K shares).

Behind Rhythm Pharmaceuticals' open-market sales in the past 12 months were 9 insiders, and no insider bought.
Jennifer Kayden Lee (EVP, Head of North America) sold the most Rhythm Pharmaceuticals stock on the open market over the past 12 months, $8.9 million (75.83K shares), most recently on August 13, 2026.
Rhythm Pharmaceuticals' latest insider trade on the open market was a sale of 50K shares for $5.13 million by David P. Meeker (President and CEO) on September 14, 2026.
In transactions other than open-market trades, Rhythm Pharmaceuticals insiders acquired 517.6K shares through option exercises and conversions and gave up 68.4K shares to cover taxes or exercise prices over the past 12 months.
Per Business Quant data, Rhythm Pharmaceuticals insiders hold 543.25K shares in total based on their latest Form 4 filings, or 0.79% of the 68.82Mn shares outstanding; that total is down 7.41% from 586.73K shares at the end of Q2 2026 and up 20.62% from 450.39K shares at the end of Q3 2025.
By type of ownership, RYTM insiders hold 97.39% of their shares directly (529.08K shares) and 2.61% indirectly (14.17K shares).
Holdings in Rhythm Pharmaceuticals stock are reported by 13 insiders, the officers, directors and 10% owners who have filed a Form 4 in the past two years.
RYTM's largest insider holders by reported holdings are David P. Meeker (President and CEO, 239.26K shares), Hunter C. Smith (Chief Financial Officer, 114.02K shares) and Yann Mazabraud (EVP, Head of International, 55.66K shares).
Of the shares held by RYTM insiders, 44.04% belong to David P. Meeker.
Over the past 12 months, 16 insiders reported transactions in Rhythm Pharmaceuticals stock in 49 Form 4 filings.
The insider data for RYTM reflects Form 4 filings through September 14, 2026.

Form 4 Holdings

Insiders Holding RYTM

Insiders 14

Shares held 544.12K

Of outstanding 0.791%

#	Insider	Position	Direct	Indirect	Total	Share of Insiders	Last Filed
1	David P Meeker	President And Ceo	239,258	0	239,258	44.0%	14 Sep, 2026
2	Hunter C Smith	Chief Financial Officer	114,024	0	114,024	21.0%	01 Sep, 2026
3	Yann Mazabraud	Evp, Head Of International	55,655	0	55,655	10.2%	14 Aug, 2026
4	Pamela J. Cramer	Chief Human Resources Officer	29,376	0	29,376	5.4%	03 Feb, 2026
5	Joseph Shulman	Chief Technical Officer	15,915	0	15,915	2.9%	17 Aug, 2026
6	Edward T Mathers	Director	0	14,168	14,168	2.6%	16 Mar, 2026
7	David W J Mcgirr	Director	11,712	0	11,712	2.2%	25 Jun, 2026
8	Jennifer L Good	Director	11,712	0	11,712	2.2%	25 Jun, 2026
9	Christophe Jean	Director	11,712	0	11,712	2.2%	25 Jun, 2026
10	Stuart A Arbuckle	Director	11,712	0	11,712	2.2%	25 Jun, 2026
11	Lynn A. Tetrault	Director	11,712	0	11,712	2.2%	25 Jun, 2026
12	William T. Roberts	Chief Accounting Officer	7,872	0	7,872	1.4%	31 Mar, 2023
13	Camille L Bedrosian	Director	7,000	0	7,000	1.3%	23 Jun, 2025
14	Alastair Garfield	Chief Scientific Officer	2,295	0	2,295	0.4%	17 Aug, 2026

Each row is that insider’s most recently reported position, from Form 4 filings over the last 60 months — which is why this total does not tie to the quarterly series above, where a quarter counts only the insiders who filed in it. Shares held through a fund or institutional portfolio are counted on the institutional ownership page instead.

Form 4 Filings

1,079 Insider Transactions

Source SEC Form 4

Latest quarter Sep 2026

Date	Insider	Position	Transaction	Shares	Price	Value	Shares Held After	Ownership
14 Sep, 2026	David P Meeker	President And Ceo	Acquired M	50,000	$6.05	$302.50K	289,258	Direct
14 Sep, 2026	David P Meeker	President And Ceo	Disposed S	6,439	$101.75	$655.15K	282,819	Direct
14 Sep, 2026	David P Meeker	President And Ceo	Disposed S	30,746	$102.35	$3.15Mn	252,073	Direct
14 Sep, 2026	David P Meeker	President And Ceo	Disposed S	8,698	$103.43	$899.63K	243,375	Direct
14 Sep, 2026	David P Meeker	President And Ceo	Disposed S	1,817	$104.55	$189.96K	241,558	Direct
14 Sep, 2026	David P Meeker	President And Ceo	Disposed S	2,300	$105.19	$241.94K	239,258	Direct
14 Sep, 2026	David P Meeker	President And Ceo	Disposed M	50,000	$0.00	$0	15,431	Direct
31 Aug, 2026	Hunter C Smith	Chief Financial Officer	Acquired M	57,187	$25.79	$1.47Mn	176,798	Direct
31 Aug, 2026	Hunter C Smith	Chief Financial Officer	Disposed S	23,072	$104.59	$2.41Mn	153,726	Direct
31 Aug, 2026	Hunter C Smith	Chief Financial Officer	Disposed S	11,514	$105.37	$1.21Mn	142,212	Direct
31 Aug, 2026	Hunter C Smith	Chief Financial Officer	Disposed S	28,188	$106.20	$2.99Mn	114,024	Direct
31 Aug, 2026	Hunter C Smith	Chief Financial Officer	Disposed M	57,187	$0.00	$0	3,813	Direct
17 Aug, 2026	Manher Joshi	Chief Medical Officer	Acquired A	50,000	$0.00	$0	50,000	Direct
17 Aug, 2026	Manher Joshi	Chief Medical Officer	Acquired A	25,000	$0.00	$0	25,000	Direct
13 Aug, 2026	Alastair Garfield	Chief Scientific Officer	Disposed S	2,007	$116.11	$233.03K	8,051	Direct
13 Aug, 2026	Joseph Shulman	Chief Technical Officer	Acquired M	2,024	$6.80	$13.76K	20,994	Direct
13 Aug, 2026	Alastair Garfield	Chief Scientific Officer	Disposed S	1,556	$117.08	$182.17K	6,495	Direct
13 Aug, 2026	Joseph Shulman	Chief Technical Officer	Disposed S	5,079	$119.75	$608.21K	15,915	Direct
13 Aug, 2026	Alastair Garfield	Chief Scientific Officer	Disposed S	3,400	$118.28	$402.17K	3,095	Direct
13 Aug, 2026	Joseph Shulman	Chief Technical Officer	Disposed M	2,024	$0.00	$0	5,945	Direct

Showing 1 to 20 of 1,079 transactions