Plus Therapeutics (PSTV) Operating Margin (2011 - 2026)

Plus Therapeutics (PSTV) reported Operating Margin of 692.51% for Q1 2026, down 35861.0% year-over-year from N/an in Q1 2025, and down 64.87% quarter-over-quarter from 420.04% in Q4 2025.

Plus Therapeutics (PSTV) Operating Margin (2011 - 2026) Analysis & Trends

Plus Therapeutics (PSTV) has 14 years of Operating Margin data on file, last reported at 692.51% in Q1 2026.

  • Operating Margin for Q1 2026 came in at 692.51%, down 35861.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 364.36% (down 7753.0% YoY), and the FY2025 annual result was 293.46%, down 4114.0% from the prior year.
  • Operating Margin slipped to 692.51% in Q1 2026 per PSTV's latest filing, from 420.04% in the prior quarter.
  • Over five years, Operating Margin peaked at 73.89% in Q3 2023 and troughed at 6978.08% in Q3 2022.
  • A 5-year average of 1043.92% and a median of 293.83% in 2023 frame the typical range for Operating Margin.
  • The sharpest annual moves came in 2023 and 2026: Operating Margin surged 690420 bps in 2023, then plunged 35861 bps in 2026.
  • A 5-year view of Operating Margin shows it stood at 4387.4% in 2022, then surged by 93 bps to 293.83% in 2023, then advanced by 6 bps to 276.2% in 2024, then plunged by 52 bps to 420.04% in 2025, then plunged by 65 bps to 692.51% in 2026.
  • Business Quant data shows PSTV's Operating Margin at 692.51% in Q1 2026, 420.04% in Q4 2025, and 320.83% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Operating Margin (Qtr)
1 Alterity Therapeutics 719,706.53 Bn 719,706.50 Bn - -
2 Belite Bio 55,800.00 Bn 55,800.00 Bn - -
3 Quantum Biopharma 18,182.30 Bn 18,182.29 Bn - -
4 Legend Biotech 3,154.00 Bn 3,153.71 Bn 242.10 Mn -6.43%
5 Akari Therapeutics 1,844.30 Bn 1,844.29 Bn - -
6 Evaxion A 1,567.96 Bn 1,567.94 Bn - -
7 Psyence Biomedical 251.43 Bn 251.42 Bn - -
8 Vertex Pharmaceuticals 112.56 Bn 105.31 Bn 2.59 Bn 38.10%
9 Abivax 94.37 Bn 94.37 Bn - -
10 Plus Therapeutics 37.48 Mn 22.37 Mn - -692.51%

Historic Data

Download Data
DateValue
Mar 31, 2026 -692.51%
Dec 31, 2025 -420.04%
Sep 30, 2025 -320.83%
Jun 30, 2025 -110.65%
Mar 31, 2025 -333.90%
Dec 31, 2024 -276.20%
Sep 30, 2024 -260.92%
Jun 30, 2024 -289.05%
Mar 31, 2024 -196.72%
Dec 31, 2023 -293.83%
Sep 30, 2023 -73.89%
Jun 30, 2023 -80.37%
Mar 31, 2023 -944.40%
Dec 31, 2022 -4,387.40%
Sep 30, 2022 -6,978.08%
Mar 31, 2019 -308.11%
Dec 31, 2018 -134.32%
Sep 30, 2018 -259.56%
Jun 30, 2018 -279.70%
Mar 31, 2018 -595.35%