BeOne Medicines (ONC) Operating Margin (2015 - 2026)

BeOne Medicines (ONC) posted quarterly Operating Margin of 16.51% for Q1 2026, up 1552.0% year-over-year from 1.0% in Q1 2025, and up 33.69% quarter-over-quarter from 12.35% in Q4 2025.

BeOne Medicines (ONC) Operating Margin (2015 - 2026) Analysis & Trends

BeOne Medicines (ONC) has reported Operating Margin for 12 consecutive years, with 16.51% the latest figure, recorded in Q1 2026.

  • In Q1 2026, Operating Margin rose 1552.0% year-over-year to 16.51%; the TTM figure through Mar 2026 stood at 11.95% (up 1903.0% YoY), while the FY2025 annual figure was 8.37%, up 2328.0% from the prior year.
  • Operating Margin improved to 16.51% in Q1 2026 per ONC's latest filing, from 12.35% in the prior quarter.
  • Across five years, Operating Margin topped out at 16.51% in Q1 2026 and bottomed at 144.57% in Q1 2022.
  • Historically, Operating Margin has averaged 43.58% across 5 years, with a median of 17.15% in 2023.
  • On a YoY basis, Operating Margin climbed as much as 18794 bps in 2022 and fell as far as 21235 bps in 2022.
  • BeOne Medicines' Operating Margin stood at 123.29% in 2022, then surged by 51 bps to 60.5% in 2023, then surged by 88 bps to 7.04% in 2024, then surged by 275 bps to 12.35% in 2025, then soared by 34 bps to 16.51% in 2026.
  • Business Quant data shows ONC's Operating Margin at 16.51% in Q1 2026, 12.35% in Q4 2025, and 11.55% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Operating Margin (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 37.40%
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 30.15%
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 31.68%
4 Revolution Medicines 43.64 Bn 43.64 Bn - -
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 19.06%
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -105.20%
7 Royalty Pharma 33.72 Bn 35.84 Bn - 19.75%
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 17.93%
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -0.36%
10 Roivant Sciences 26.16 Bn 26.85 Bn 1.16 Mn -25,380.93%

Historic Data

Download Data
DateValue
Jun 30, 2026 19.06%
Mar 31, 2026 16.51%
Dec 31, 2025 12.35%
Sep 30, 2025 11.55%
Jun 30, 2025 6.68%
Mar 31, 2025 0.99%
Dec 31, 2024 -7.04%
Sep 30, 2024 -12.01%
Jun 30, 2024 -11.53%
Mar 31, 2024 -34.77%
Dec 31, 2023 -60.50%
Sep 30, 2023 -17.15%
Jun 30, 2023 -53.54%
Mar 31, 2023 -82.91%
Dec 31, 2022 -123.29%
Sep 30, 2022 -113.09%
Jun 30, 2022 -128.64%
Mar 31, 2022 -144.57%
Dec 31, 2021 89.06%
Sep 30, 2021 -223.95%