BeOne Medicines (ONC) Operating Margin (2015 - 2026)

BeOne Medicines' (ONC) quarterly Operating Margin came in at 16.51% in Q1 2026, up 1552.0% year-on-year from 1.0% in Q1 2025, and up 33.69% on a QoQ basis from 12.35% in Q4 2025.

BeOne Medicines (ONC) Operating Margin (2015 - 2026) Analysis & Trends

BeOne Medicines (ONC) has 12 years of Operating Margin data on file, last reported at 16.51% in Q1 2026.

  • On a quarterly basis, Operating Margin rose 1552.0% year-over-year to 16.51% in Q1 2026; TTM through Mar 2026 was 11.95%, a 1903.0% increase from a year earlier, with the FY2025 full-year figure at 8.37%, up 2328.0% from the prior year.
  • Operating Margin for Q1 2026 stood at 16.51%, up from 12.35% in the prior quarter.
  • Over the last five years, Operating Margin for ONC reached as high as 16.51% in Q1 2026 and fell as low as 144.57% in Q1 2022.
  • Historically, Operating Margin has averaged 43.58% across 5 years, with a median of 17.15% in 2023.
  • On a YoY basis, Operating Margin climbed as much as 18794 bps in 2022 and fell as far as 21235 bps in 2022.
  • Year by year, Operating Margin stood at 123.29% in 2022, then jumped by 51 bps to 60.5% in 2023, then jumped by 88 bps to 7.04% in 2024, then jumped by 275 bps to 12.35% in 2025, then surged by 34 bps to 16.51% in 2026.
  • Per Business Quant data, the three most recent Operating Margin figures were 16.51% in Q1 2026, 12.35% in Q4 2025, and 11.55% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Operating Margin (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 16.51%
4 NuCana 279.75 Bn 279.75 Bn - -
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 38.10%
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 17.83%
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 31.68%
9 Revolution Medicines 37.78 Bn 37.78 Bn - -
10 Alnylam Pharmaceuticals 35.71 Bn 32.70 Bn 959.66 Mn 23.02%

Historic Data

Download Data
DateValue
Mar 31, 2026 16.51%
Dec 31, 2025 12.35%
Sep 30, 2025 11.55%
Jun 30, 2025 6.68%
Mar 31, 2025 0.99%
Dec 31, 2024 -7.04%
Sep 30, 2024 -12.01%
Jun 30, 2024 -11.53%
Mar 31, 2024 -34.77%
Dec 31, 2023 -60.50%
Sep 30, 2023 -17.15%
Jun 30, 2023 -53.54%
Mar 31, 2023 -82.91%
Dec 31, 2022 -123.29%
Sep 30, 2022 -113.09%
Jun 30, 2022 -128.64%
Mar 31, 2022 -144.57%
Dec 31, 2021 89.06%
Sep 30, 2021 -223.95%
Jun 30, 2021 -316.58%