BeOne Medicines (ONC) Operating Margin (2015 - 2026)
BeOne Medicines (ONC) reported Operating Margin of 16.51% for Q1 2026, up 1552.0% year-over-year from 1.0% in Q1 2025, and up 33.69% on a QoQ basis from 12.35% in Q4 2025.
BeOne Medicines (ONC) has 12 years of Operating Margin data on file, last reported at 16.51% in Q1 2026.
- Quarterly Operating Margin rose 1552.0% year-over-year to 16.51% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 11.95% (up 1903.0% YoY) and the FY2025 annual result came in at 8.37%, up 2328.0% from the prior year.
- Operating Margin advanced to 16.51% in Q1 2026 per ONC's latest filing, from 12.35% in the prior quarter.
- Across five years, Operating Margin topped out at 16.51% in Q1 2026 and bottomed at 144.57% in Q1 2022.
- The 5-year median for Operating Margin is 17.15% (2023), against an average of 43.58%.
- Peak annual rise in Operating Margin reached 18794 bps in 2022, while the deepest fall reached 21235 bps in 2022.
- Tracing ONC's Operating Margin over 5 years: stood at 123.29% in 2022, then surged by 51 bps to 60.5% in 2023, then surged by 88 bps to 7.04% in 2024, then surged by 275 bps to 12.35% in 2025, then soared by 34 bps to 16.51% in 2026.
- Per Business Quant, the three latest ONC Operating Margin figures stand at 16.51% (Q1 2026), 12.35% (Q4 2025), and 11.55% (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 1,384,976.65 Bn | 1,384,976.64 Bn | - | - |
| 2 | Alterity Therapeutics | 777,208.84 Bn | 777,208.81 Bn | - | - |
| 3 | Legend Biotech | 2,801.00 Bn | 2,800.10 Bn | 242.10 Mn | -6.43% |
| 4 | Nanobiotix | 2,226.01 Bn | 2,225.95 Bn | - | - |
| 5 | Akari Therapeutics | 605.66 Bn | 605.66 Bn | - | - |
| 6 | Vertex Pharmaceuticals | 110.17 Bn | 102.92 Bn | 2.59 Bn | 38.10% |
| 7 | Regeneron Pharmaceuticals | 66.86 Bn | 58.11 Bn | 3.31 Bn | 17.83% |
| 8 | Evaxion A | 65.12 Bn | 65.10 Bn | - | - |
| 9 | Alnylam Pharmaceuticals | 39.94 Bn | 36.94 Bn | 959.66 Mn | 23.02% |
| 10 | BeOne Medicines | - | - | 1.35 Bn | 16.51% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 16.51% |
| Dec 31, 2025 | 12.35% |
| Sep 30, 2025 | 11.55% |
| Jun 30, 2025 | 6.68% |
| Mar 31, 2025 | 0.99% |
| Dec 31, 2024 | -7.04% |
| Sep 30, 2024 | -12.01% |
| Jun 30, 2024 | -11.53% |
| Mar 31, 2024 | -34.77% |
| Dec 31, 2023 | -60.50% |
| Sep 30, 2023 | -17.15% |
| Jun 30, 2023 | -53.54% |
| Mar 31, 2023 | -82.91% |
| Dec 31, 2022 | -123.29% |
| Sep 30, 2022 | -113.09% |
| Jun 30, 2022 | -128.64% |
| Mar 31, 2022 | -144.57% |
| Dec 31, 2021 | 89.06% |
| Sep 30, 2021 | -223.95% |
| Jun 30, 2021 | -316.58% |
| Mar 31, 2021 | 11.58% |
| Dec 31, 2020 | -484.43% |
| Sep 30, 2020 | -483.24% |
| Jun 30, 2020 | -546.78% |
| Mar 31, 2020 | -717.95% |
| Dec 31, 2019 | -682.06% |
| Sep 30, 2019 | -622.78% |
| Jun 30, 2019 | -57.22% |
| Mar 31, 2019 | -223.24% |
| Dec 31, 2018 | -478.62% |
| Sep 30, 2018 | -278.78% |
| Jun 30, 2018 | -308.78% |
| Mar 31, 2018 | -340.49% |
| Dec 31, 2017 | -571.13% |
| Sep 30, 2017 | 52.18% |
| Jun 30, 2016 | -6,266.67% |
| Mar 31, 2016 | -3,003.55% |
| Dec 31, 2015 | -563.95% |
| Sep 30, 2015 | -1,013.91% |
| Jun 30, 2015 | -475.72% |
| Mar 31, 2015 | -711.53% |