Insmed (INSM) Operating Margin (2010 - 2026)
Insmed (INSM) recorded quarterly Operating Margin of 50.11% in Q1 2026, up 58.65% quarter-over-quarter from 121.19% in Q4 2025, and up 21722.0% on a YoY basis from N/an in Q1 2025.
Insmed (INSM) Operating Margin (2010 - 2026) Analysis & Trends
Insmed's Operating Margin history runs 12 years deep, the most recent figure standing at 50.11% for Q1 2026.
- In Q1 2026, Operating Margin rose 21722.0% year-over-year to 50.11%; the TTM figure through Mar 2026 stood at 140.56% (up 11687.0% YoY), while the FY2025 annual figure was 205.59%, up 3588.0% from the prior year.
- Operating Margin was 50.11% for Q1 2026 at Insmed, up from 121.19% in the prior quarter.
- In the past five years, Operating Margin ranged from a high of 50.11% in Q1 2026 to a low of 319.8% in Q2 2024.
- Historically, Operating Margin has averaged 213.48% across 5 years, with a median of 220.61% in 2024.
- The sharpest annual moves came in 2023 and 2026: Operating Margin sank 16956 bps in 2023, then jumped 21722 bps in 2026.
- A 5-year view of Operating Margin shows it stood at 255.44% in 2022, then gained by 17 bps to 213.01% in 2023, then declined by 4 bps to 220.61% in 2024, then soared by 45 bps to 121.19% in 2025, then jumped by 59 bps to 50.11% in 2026.
- The last three Operating Margin figures came in at 50.11% (Q1 2026), 121.19% (Q4 2025), and 257.13% (Q3 2025), per Business Quant data.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 762,369.55 Bn | 762,369.51 Bn | - | - |
| 2 | Belite Bio | 55,096.00 Bn | 55,096.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,755.80 Bn | 17,755.79 Bn | - | - |
| 4 | Legend Biotech | 3,486.00 Bn | 3,485.71 Bn | 242.10 Mn | -6.43% |
| 5 | Akari Therapeutics | 1,737.42 Bn | 1,737.41 Bn | - | - |
| 6 | Evaxion A | 1,551.28 Bn | 1,551.26 Bn | - | - |
| 7 | Psyence Biomedical | 227.32 Bn | 227.31 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 110.84 Bn | 103.59 Bn | 2.59 Bn | 38.10% |
| 9 | Abivax | 91.71 Bn | 91.71 Bn | - | - |
| 10 | Insmed | 19.79 Bn | 18.57 Bn | 258.54 Mn | -50.11% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -50.11% |
| Dec 31, 2025 | -121.19% |
| Sep 30, 2025 | -257.13% |
| Jun 30, 2025 | -291.28% |
| Mar 31, 2025 | -267.33% |
| Dec 31, 2024 | -220.61% |
| Sep 30, 2024 | -228.45% |
| Jun 30, 2024 | -319.80% |
| Mar 31, 2024 | -192.72% |
| Dec 31, 2023 | -213.01% |
| Sep 30, 2023 | -186.75% |
| Jun 30, 2023 | -304.97% |
| Mar 31, 2023 | -227.19% |
| Dec 31, 2022 | -255.44% |
| Sep 30, 2022 | -188.54% |
| Jun 30, 2022 | -135.41% |
| Mar 31, 2022 | -169.15% |
| Dec 31, 2021 | -176.53% |
| Sep 30, 2021 | -221.61% |
| Jun 30, 2021 | -195.23% |