Insmed (INSM) Operating Margin (2010 - 2026)
Insmed (INSM) posted quarterly Operating Margin of 50.11% for Q1 2026, up 21722.0% year-over-year from N/an in Q1 2025, and up 58.65% quarter-over-quarter from 121.19% in Q4 2025.
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Insmed (INSM) Operating Margin (2010 - 2026) Analysis & Trends
Insmed's Operating Margin history runs 12 years deep, the most recent figure standing at 50.11% for Q1 2026.
- In Q1 2026, Operating Margin rose 21722.0% year-over-year to 50.11%; the TTM figure through Mar 2026 stood at 140.56% (up 11687.0% YoY), while the FY2025 annual figure was 205.59%, up 3588.0% from the prior year.
- Operating Margin for Q1 2026 stood at 50.11%, up from 121.19% in the prior quarter.
- The five-year high for Operating Margin was 50.11% in Q1 2026, with the low at 319.8% in Q2 2024.
- The 5-year median for Operating Margin is 220.61% (2024), against an average of 213.48%.
- The sharpest annual moves came in 2023 and 2026: Operating Margin plunged 16956 bps in 2023, then soared 21722 bps in 2026.
- Insmed's Operating Margin stood at 255.44% in 2022, then rose by 17 bps to 213.01% in 2023, then dropped by 4 bps to 220.61% in 2024, then surged by 45 bps to 121.19% in 2025, then soared by 59 bps to 50.11% in 2026.
- Business Quant data shows INSM's Operating Margin at 50.11% in Q1 2026, 121.19% in Q4 2025, and 257.13% in Q3 2025.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 138.47 Bn | 130.62 Bn | 2.84 Bn | 37.40% |
| 2 | Regeneron Pharmaceuticals | 85.18 Bn | 77.19 Bn | 3.93 Bn | 30.15% |
| 3 | Argenx Se | 63.38 Bn | 58.19 Bn | 1.37 Bn | 32.54% |
| 4 | Moderna | 58.09 Bn | 52.95 Bn | 52.00 Mn | -562.07% |
| 5 | Revolution Medicines | 44.33 Bn | 44.33 Bn | - | - |
| 6 | BeOne Medicines | 40.02 Bn | 34.92 Bn | 1.53 Bn | 19.06% |
| 7 | Alnylam Pharmaceuticals | 35.57 Bn | 32.27 Bn | 992.69 Mn | 17.93% |
| 8 | Royalty Pharma | 28.45 Bn | 27.61 Bn | - | 19.75% |
| 9 | Insmed | 27.48 Bn | 26.32 Bn | 358.27 Mn | -0.36% |
| 10 | Incyte | 25.44 Bn | 20.91 Bn | 1.57 Bn | 41.69% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -0.36% |
| Mar 31, 2026 | -50.11% |
| Dec 31, 2025 | -121.19% |
| Sep 30, 2025 | -257.13% |
| Jun 30, 2025 | -291.28% |
| Mar 31, 2025 | -267.33% |
| Dec 31, 2024 | -220.61% |
| Sep 30, 2024 | -228.45% |
| Jun 30, 2024 | -319.80% |
| Mar 31, 2024 | -192.72% |
| Dec 31, 2023 | -213.01% |
| Sep 30, 2023 | -186.75% |
| Jun 30, 2023 | -304.97% |
| Mar 31, 2023 | -227.19% |
| Dec 31, 2022 | -255.44% |
| Sep 30, 2022 | -188.54% |
| Jun 30, 2022 | -135.41% |
| Mar 31, 2022 | -169.15% |
| Dec 31, 2021 | -176.53% |
| Sep 30, 2021 | -221.61% |