Insmed (INSM) Operating Margin (2010 - 2026)
Insmed's (INSM) quarterly Operating Margin came in at 50.11% in Q1 2026, up 21722.0% year-on-year from N/an in Q1 2025, and up 58.65% quarter-over-quarter from 121.19% in Q4 2025.
Insmed (INSM) Operating Margin (2010 - 2026) Analysis & Trends
Insmed's Operating Margin history runs 12 years deep, the most recent figure standing at 50.11% for Q1 2026.
- On a quarterly basis, Operating Margin rose 21722.0% year-over-year to 50.11% in Q1 2026; TTM through Mar 2026 was 140.56%, a 11687.0% increase from a year earlier, with the FY2025 full-year figure at 205.59%, up 3588.0% from the prior year.
- Operating Margin advanced to 50.11% in Q1 2026 per INSM's latest filing, from 121.19% in the prior quarter.
- Across five years, Operating Margin topped out at 50.11% in Q1 2026 and bottomed at 319.8% in Q2 2024.
- The 5-year median for Operating Margin is 220.61% (2024), against an average of 213.48%.
- Across the five-year window, Operating Margin sank 16956 bps in 2023 and soared 21722 bps in 2026, its largest moves.
- Year by year, Operating Margin stood at 255.44% in 2022, then gained by 17 bps to 213.01% in 2023, then declined by 4 bps to 220.61% in 2024, then soared by 45 bps to 121.19% in 2025, then jumped by 59 bps to 50.11% in 2026.
- Per Business Quant, the three latest INSM Operating Margin figures stand at 50.11% (Q1 2026), 121.19% (Q4 2025), and 257.13% (Q3 2025).
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | - |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | - |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | 16.51% |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | - |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | 38.10% |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | 17.83% |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | - |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | 31.68% |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | - |
| 10 | Insmed | 23.26 Bn | 22.03 Bn | 258.54 Mn | -50.11% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -50.11% |
| Dec 31, 2025 | -121.19% |
| Sep 30, 2025 | -257.13% |
| Jun 30, 2025 | -291.28% |
| Mar 31, 2025 | -267.33% |
| Dec 31, 2024 | -220.61% |
| Sep 30, 2024 | -228.45% |
| Jun 30, 2024 | -319.80% |
| Mar 31, 2024 | -192.72% |
| Dec 31, 2023 | -213.01% |
| Sep 30, 2023 | -186.75% |
| Jun 30, 2023 | -304.97% |
| Mar 31, 2023 | -227.19% |
| Dec 31, 2022 | -255.44% |
| Sep 30, 2022 | -188.54% |
| Jun 30, 2022 | -135.41% |
| Mar 31, 2022 | -169.15% |
| Dec 31, 2021 | -176.53% |
| Sep 30, 2021 | -221.61% |
| Jun 30, 2021 | -195.23% |