Moderna (MRNA) Operating Margin (2017 - 2026)
Moderna's (MRNA) quarterly Operating Margin came in at 356.81% in Q1 2026, up 61541.0% year-on-year from N/an in Q1 2025, and down 182.29% on a QoQ basis from 126.4% in Q4 2025.
Moderna (MRNA) Operating Margin (2017 - 2026) Analysis & Trends
Moderna (MRNA) has 10 years of Operating Margin data on file, last reported at 356.81% in Q1 2026.
- On a quarterly basis, Operating Margin rose 61541.0% year-over-year to 356.81% in Q1 2026; TTM through Mar 2026 was 153.35%, a 3597.0% decrease from a year earlier, with the FY2025 full-year figure at 158.13%, down 3622.0% from the prior year.
- Operating Margin for Q1 2026 stood at 356.81%, down from 126.4% in the prior quarter.
- Over the last five years, Operating Margin for MRNA reached as high as 69.68% in Q1 2022 and fell as low as 972.22% in Q1 2025.
- Historically, Operating Margin has averaged 238.9% across 5 years, with a median of 109.89% in 2023.
- Across the five-year window, Operating Margin sank 73843 bps in 2024 and surged 61541 bps in 2026, its largest moves.
- Year by year, Operating Margin stood at 31.08% in 2022, then slumped by 99 bps to 0.21% in 2023, then slumped by 60530 bps to 128.99% in 2024, then rose by 2 bps to 126.4% in 2025, then tumbled by 182 bps to 356.81% in 2026.
- Per Business Quant data, the three most recent Operating Margin figures were 356.81% in Q1 2026, 126.4% in Q4 2025, and 25.59% in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | - |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | - |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | 16.51% |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | - |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | 38.10% |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | 17.83% |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | - |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | 31.68% |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | - |
| 10 | Moderna | 22.52 Bn | 17.32 Bn | -566.00 Mn | -356.81% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -356.81% |
| Dec 31, 2025 | -126.40% |
| Sep 30, 2025 | -25.59% |
| Jun 30, 2025 | -638.73% |
| Mar 31, 2025 | -972.22% |
| Dec 31, 2024 | -128.99% |
| Sep 30, 2024 | -3.76% |
| Jun 30, 2024 | -565.56% |
| Mar 31, 2024 | -758.08% |
| Dec 31, 2023 | 0.21% |
| Sep 30, 2023 | -109.89% |
| Jun 30, 2023 | -542.73% |
| Mar 31, 2023 | -19.66% |
| Dec 31, 2022 | 31.08% |
| Sep 30, 2022 | 34.66% |
| Jun 30, 2022 | 51.53% |
| Mar 31, 2022 | 69.68% |
| Dec 31, 2021 | 75.02% |
| Sep 30, 2021 | 71.60% |
| Jun 30, 2021 | 70.33% |