Moderna (MRNA) Operating Margin (2017 - 2026)
Moderna (MRNA) reported Operating Margin of 356.81% for Q1 2026, up 61541.0% year-over-year from N/an in Q1 2025, and down 182.29% quarter-over-quarter from 126.4% in Q4 2025.
Moderna (MRNA) Operating Margin (2017 - 2026) Analysis & Trends
Moderna (MRNA) has 10 years of Operating Margin data on file, last reported at 356.81% in Q1 2026.
- Operating Margin for Q1 2026 came in at 356.81%, up 61541.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 153.35% (down 3352.0% YoY), and the FY2025 annual result was 158.13%, down 3622.0% from the prior year.
- Operating Margin slipped to 356.81% in Q1 2026 per MRNA's latest filing, from 126.4% in the prior quarter.
- Over five years, Operating Margin peaked at 69.68% in Q1 2022 and troughed at 972.22% in Q1 2025.
- A 5-year average of 251.18% and a median of 109.89% in 2023 frame the typical range for Operating Margin.
- The sharpest annual moves came in 2024 and 2026: Operating Margin tumbled 73843 bps in 2024, then jumped 61541 bps in 2026.
- A 5-year view of Operating Margin shows it stood at 31.08% in 2022, then sank by 99 bps to 0.21% in 2023, then sank by 60530 bps to 128.99% in 2024, then climbed by 2 bps to 126.4% in 2025, then slumped by 182 bps to 356.81% in 2026.
- Business Quant data shows MRNA's Operating Margin at 356.81% in Q1 2026, 126.4% in Q4 2025, and 25.59% in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | - |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -6.43% |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | - |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 38.10% |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | - |
| 10 | Moderna | 25.27 Bn | 20.06 Bn | -566.00 Mn | -356.81% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -356.81% |
| Dec 31, 2025 | -126.40% |
| Sep 30, 2025 | -25.59% |
| Jun 30, 2025 | -638.73% |
| Mar 31, 2025 | -972.22% |
| Dec 31, 2024 | -128.99% |
| Sep 30, 2024 | -3.76% |
| Jun 30, 2024 | -774.43% |
| Mar 31, 2024 | -758.08% |
| Dec 31, 2023 | 0.21% |
| Sep 30, 2023 | -109.89% |
| Jun 30, 2023 | -542.73% |
| Mar 31, 2023 | -19.66% |
| Dec 31, 2022 | 31.08% |
| Sep 30, 2022 | 34.66% |
| Jun 30, 2022 | 51.53% |
| Mar 31, 2022 | 69.68% |
| Dec 31, 2021 | 75.02% |
| Sep 30, 2021 | 71.60% |
| Jun 30, 2021 | 70.33% |