Growth Metrics

Regeneron Pharmaceuticals (REGN) Operating Margin (2009 - 2026)

Regeneron Pharmaceuticals' quarterly Operating Margin came in at 17.83% in Q1 2026, down 170.0% year-on-year from 25.47% in Q1 2025, and down 21.28% quarter-over-quarter from 22.65% in Q4 2025.

Regeneron Pharmaceuticals has reported Operating Margin for 18 years, with the latest figure at 17.83% in Q1 2026.

  • For the quarter ending Q1 2026, Operating Margin fell 170.0% year-over-year to 17.83%; the trailing twelve-month figure through Mar 2026 stood at 24.32% (down 287.0% YoY), and the FY2025 full-year result was 24.95%, down 315.0% from the prior year.
  • Operating Margin for Q1 2026 stood at 17.83%, down from 22.65% in the prior quarter.
  • The five-year high for Operating Margin was 2517.0% in Q1 2022, with the low at 17.83% in Q1 2026.
  • Average Operating Margin over 5 years is 240.97%, with a median of 29.94% recorded in 2023.
  • Year-over-year, Operating Margin soared 247300 bps in 2022 and sank 248706 bps in 2023.
  • Tracing REGN's Operating Margin over 5 years: stood at 1146.8% in 2022, then tumbled by 98 bps to 28.33% in 2023, then dropped by 8 bps to 26.13% in 2024, then slipped by 13 bps to 22.65% in 2025, then slipped by 21 bps to 17.83% in 2026.
  • The last three Operating Margin figures came in at 17.83% (Q1 2026), 22.65% (Q4 2025), and 27.35% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Operating Margin (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -6.43%
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 38.10%
7 Evaxion A 62.56 Bn 62.54 Bn - -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 17.83%
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 23.02%
10 Revolution Medicines 32.39 Bn 32.39 Bn - -

Historic Data

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DateValue
Mar 31, 2026 17.83%
Dec 31, 2025 22.65%
Sep 30, 2025 27.35%
Jun 30, 2025 29.37%
Mar 31, 2025 19.54%
Dec 31, 2024 26.13%
Sep 30, 2024 31.70%
Jun 30, 2024 30.15%
Mar 31, 2024 23.89%
Dec 31, 2023 28.33%
Sep 30, 2023 33.04%
Jun 30, 2023 32.19%
Mar 31, 2023 29.94%
Dec 31, 2022 1,146.80%
Sep 30, 2022 41.68%
Jun 30, 2022 38.85%
Mar 31, 2022 2,517.00%
Dec 31, 2021 53.31%
Sep 30, 2021 53.50%
Jun 30, 2021 65.14%
Mar 31, 2021 44.00%
Dec 31, 2020 48.17%
Sep 30, 2020 45.91%
Jun 30, 2020 33.63%
Mar 31, 2020 38.29%
Dec 31, 2019 36.26%
Sep 30, 2019 42.35%
Jun 30, 2019 20.00%
Mar 31, 2019 34.97%
Dec 31, 2018 37.25%
Sep 30, 2018 37.69%
Jun 30, 2018 38.69%
Mar 31, 2018 37.53%
Dec 31, 2017 34.05%
Sep 30, 2017 37.31%
Jun 30, 2017 37.43%
Mar 31, 2017 32.64%
Dec 31, 2016 28.28%
Sep 30, 2016 29.73%
Jun 30, 2016 24.05%
Mar 31, 2016 27.42%
Dec 31, 2015 21.04%
Sep 30, 2015 34.50%
Jun 30, 2015 34.53%
Mar 31, 2015 32.61%
Dec 31, 2014 30.83%
Sep 30, 2014 25.97%
Jun 30, 2014 34.26%
Mar 31, 2014 30.61%
Dec 31, 2013 31.96%
Sep 30, 2013 39.66%
Jun 30, 2013 34.55%
Mar 31, 2013 34.81%
Dec 31, 2012 35.13%
Sep 30, 2012 47.32%
Jun 30, 2012 28.74%
Mar 31, 2012 9.58%
Dec 31, 2011 -36.92%
Sep 30, 2011 -56.85%
Jun 30, 2011 -55.95%
Mar 31, 2011 -36.52%
Dec 31, 2010 97.98%
Sep 30, 2010 -650.20%
Jun 30, 2010 -20.47%
Mar 31, 2010 -1,531.12%
Dec 31, 2009 -300.02%
Sep 30, 2009 -1.10%
Jun 30, 2009 -361.47%