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Regeneron Pharmaceuticals (REGN) Operating Margin (2016 - 2025)

Regeneron Pharmaceuticals (REGN) has 17 years of Operating Margin data on record, last reported at 22.65% in Q4 2025.

  • For Q4 2025, Operating Margin rose 945313.0% year-over-year to 22.65%; the TTM value through Dec 2025 reached 24.95%, down 3339.0%, while the annual FY2025 figure was 24.95%, 315.0% down from the prior year.
  • Operating Margin reached 22.65% in Q4 2025 per REGN's latest filing, down from 27.35% in the prior quarter.
  • Across five years, Operating Margin topped out at 46488.89% in Q2 2021 and bottomed at 9430.48% in Q4 2024.
  • Average Operating Margin over 5 years is 1405.75%, with a median of 28.36% recorded in 2025.
  • Peak YoY movement for Operating Margin: surged 4645526bps in 2021, then tumbled -4426909bps in 2022.
  • A 5-year view of Operating Margin shows it stood at 21.74% in 2021, then soared by 5174bps to 1146.8% in 2022, then plummeted by -564bps to 5316.39% in 2023, then tumbled by -77bps to 9430.48% in 2024, then skyrocketed by 100bps to 22.65% in 2025.
  • Per Business Quant database, its latest 3 readings for Operating Margin were 22.65% in Q4 2025, 27.35% in Q3 2025, and 29.37% in Q2 2025.