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Regeneron Pharmaceuticals (REGN) Operating Margin (2016 - 2025)

Regeneron Pharmaceuticals has reported Operating Margin over the past 17 years, most recently at 22.65% for Q4 2025.

  • Quarterly results put Operating Margin at 22.65% for Q4 2025, down 348.0% from a year ago — trailing twelve months through Dec 2025 was 24.95% (down 315.0% YoY), and the annual figure for FY2025 was 24.95%, down 315.0%.
  • Operating Margin for Q4 2025 was 22.65% at Regeneron Pharmaceuticals, down from 27.35% in the prior quarter.
  • Over the last five years, Operating Margin for REGN hit a ceiling of 2517.0% in Q1 2022 and a floor of 19.54% in Q1 2025.
  • Median Operating Margin over the past 5 years was 31.94% (2023), compared with a mean of 352.93%.
  • Biggest five-year swings in Operating Margin: soared 247300bps in 2022 and later crashed -248706bps in 2023.
  • Regeneron Pharmaceuticals' Operating Margin stood at 2199.75% in 2021, then dropped by -20bps to 1764.31% in 2022, then crashed by -98bps to 28.33% in 2023, then dropped by -8bps to 26.13% in 2024, then fell by -13bps to 22.65% in 2025.
  • The last three reported values for Operating Margin were 22.65% (Q4 2025), 27.35% (Q3 2025), and 29.37% (Q2 2025) per Business Quant data.