Regeneron Pharmaceuticals (REGN) Operating Margin (2009 - 2026)

Regeneron Pharmaceuticals' (REGN) quarterly Operating Margin came in at 17.83% in Q1 2026, down 170.0% year-on-year from 25.47% in Q1 2025, and down 21.28% quarter-over-quarter from 22.65% in Q4 2025.

Regeneron Pharmaceuticals (REGN) Operating Margin (2009 - 2026) Analysis & Trends

Regeneron Pharmaceuticals' Operating Margin history runs 18 years deep, the most recent figure standing at 17.83% for Q1 2026.

  • On a quarterly basis, Operating Margin fell 170.0% year-over-year to 17.83% in Q1 2026; TTM through Mar 2026 was 24.32%, a 287.0% decrease from a year earlier, with the FY2025 full-year figure at 24.95%, down 315.0% from the prior year.
  • Operating Margin eased to 17.83% in Q1 2026 per REGN's latest filing, from 22.65% in the prior quarter.
  • Across five years, Operating Margin topped out at 2517.0% in Q1 2022 and bottomed at 17.83% in Q1 2026.
  • The 5-year median for Operating Margin is 29.94% (2023), against an average of 240.97%.
  • Across the five-year window, Operating Margin soared 247300 bps in 2022 and sank 248706 bps in 2023, its largest moves.
  • Year by year, Operating Margin stood at 1146.8% in 2022, then slumped by 98 bps to 28.33% in 2023, then slipped by 8 bps to 26.13% in 2024, then decreased by 13 bps to 22.65% in 2025, then decreased by 21 bps to 17.83% in 2026.
  • Per Business Quant, the three latest REGN Operating Margin figures stand at 17.83% (Q1 2026), 22.65% (Q4 2025), and 27.35% (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Operating Margin (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 16.51%
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 38.10%
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 17.83%
7 Belite Bio 61.40 Bn 61.40 Bn - -
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn 30.35%
9 Revolution Medicines 37.37 Bn 37.37 Bn - -
10 Alnylam Pharmaceuticals 36.08 Bn 33.07 Bn 959.66 Mn 23.02%

Historic Data

Download Data
DateValue
Mar 31, 2026 17.83%
Dec 31, 2025 22.65%
Sep 30, 2025 27.35%
Jun 30, 2025 29.37%
Mar 31, 2025 19.54%
Dec 31, 2024 26.13%
Sep 30, 2024 31.70%
Jun 30, 2024 30.15%
Mar 31, 2024 23.89%
Dec 31, 2023 28.33%
Sep 30, 2023 33.04%
Jun 30, 2023 32.19%
Mar 31, 2023 29.94%
Dec 31, 2022 1,146.80%
Sep 30, 2022 41.68%
Jun 30, 2022 38.85%
Mar 31, 2022 2,517.00%
Dec 31, 2021 53.31%
Sep 30, 2021 53.50%
Jun 30, 2021 65.14%